NUP205 and NUP93

Number of citations of the paper that reports this interaction (PubMedID 9348540)
86

Data Source:
HPRD (in vivo)

		NUP205	NUP93
Description		nucleoporin 205	nucleoporin 93
Image
GO Annotations	Cellular Component	Nucleus Nuclear Envelope Nuclear Pore Cytosol Membrane Nuclear Membrane Nuclear Periphery Nuclear Pore Inner Ring	Nucleus Nuclear Envelope Nuclear Pore Centrosome Cytosol Membrane Nuclear Membrane Nuclear Periphery
	Molecular Function	Protein Binding Structural Constituent Of Nuclear Pore	Protein Binding Structural Constituent Of Nuclear Pore
	Biological Process	Nucleocytoplasmic Transport Nuclear Pore Organization Protein Transport MRNA Transport Nuclear Pore Complex Assembly	Protein Import Into Nucleus Nucleocytoplasmic Transport Nuclear Envelope Organization Protein Transport Poly(A)+ MRNA Export From Nucleus MRNA Transport Nuclear Pore Complex Assembly Positive Regulation Of SMAD Protein Signal Transduction
Pathways		ISG15 antiviral mechanism Transport of the SLBP independent Mature mRNA Transport of the SLBP Dependant Mature mRNA Transport of Mature mRNA Derived from an Intronless Transcript Transport of Mature mRNA derived from an Intron-Containing Transcript Rev-mediated nuclear export of HIV RNA Transport of Ribonucleoproteins into the Host Nucleus NS1 Mediated Effects on Host Pathways Viral Messenger RNA Synthesis NEP/NS2 Interacts with the Cellular Export Machinery Regulation of Glucokinase by Glucokinase Regulatory Protein Nuclear import of Rev protein Vpr-mediated nuclear import of PICs IPs transport between nucleus and cytosol IP3 and IP4 transport between cytosol and nucleus IP6 and IP7 transport between cytosol and nucleus snRNP Assembly SUMOylation of DNA damage response and repair proteins SUMOylation of ubiquitinylation proteins Nuclear Pore Complex (NPC) Disassembly Regulation of HSF1-mediated heat shock response SUMOylation of SUMOylation proteins SUMOylation of chromatin organization proteins SUMOylation of RNA binding proteins SUMOylation of DNA replication proteins SUMOylation of DNA replication proteins Transcriptional regulation by small RNAs Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC) tRNA processing in the nucleus HCMV Early Events HCMV Late Events Postmitotic nuclear pore complex (NPC) reformation Postmitotic nuclear pore complex (NPC) reformation SARS-CoV-2 activates/modulates innate and adaptive immune responses	ISG15 antiviral mechanism Transport of the SLBP independent Mature mRNA Transport of the SLBP Dependant Mature mRNA Transport of Mature mRNA Derived from an Intronless Transcript Transport of Mature mRNA derived from an Intron-Containing Transcript Rev-mediated nuclear export of HIV RNA Transport of Ribonucleoproteins into the Host Nucleus NS1 Mediated Effects on Host Pathways Viral Messenger RNA Synthesis NEP/NS2 Interacts with the Cellular Export Machinery Regulation of Glucokinase by Glucokinase Regulatory Protein Nuclear import of Rev protein Vpr-mediated nuclear import of PICs IPs transport between nucleus and cytosol IP3 and IP4 transport between cytosol and nucleus IP6 and IP7 transport between cytosol and nucleus snRNP Assembly SUMOylation of DNA damage response and repair proteins SUMOylation of ubiquitinylation proteins Nuclear Pore Complex (NPC) Disassembly Regulation of HSF1-mediated heat shock response SUMOylation of SUMOylation proteins SUMOylation of chromatin organization proteins SUMOylation of RNA binding proteins SUMOylation of DNA replication proteins SUMOylation of DNA replication proteins Transcriptional regulation by small RNAs Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC) tRNA processing in the nucleus HCMV Early Events HCMV Late Events Postmitotic nuclear pore complex (NPC) reformation Postmitotic nuclear pore complex (NPC) reformation SARS-CoV-2 activates/modulates innate and adaptive immune responses
Drugs
Diseases
GWAS		Age at first sexual intercourse ( 34211149) Apolipoprotein A1 levels ( 32203549) Cognitive ability, years of educational attainment or schizophrenia (pleiotropy) ( 31374203) Eosinophil count ( 32888494) Eosinophil percentage of white cells ( 32888494) Meat-related diet ( 32066663) Paget's disease ( 21623375) Post bronchodilator FEV1 ( 26634245) Post bronchodilator FEV1/FVC ratio ( 26634245) Red blood cell count ( 32888494) Venous thromboembolism adjusted for sickle cell variant rs77121243-T ( 28203683) Waist-hip index ( 34021172) Waist-to-hip ratio adjusted for BMI ( 34021172)	Apolipoprotein A1 levels ( 32203549) Apolipoprotein B levels ( 32203549) Gambling ( 22780124) HDL cholesterol ( 20031564) HDL cholesterol levels ( 26763881 32203549) Potassium levels ( 29403010)
Interacting Genes		4 interacting genes: HOXC10 NUP35 NUP93 NUP98	10 interacting genes: AP5Z1 CEBPA GRSF1 MPPED2 NDC1 NUP205 NUP35 OPCML PLA2G6 TMEM100
Entrez ID		23165	9688
HPRD ID		17653	14854
Ensembl ID		ENSG00000155561	ENSG00000102900
Uniprot IDs		Q92621	Q8N1F7
PDB IDs		5IJN 5IJO 7PER 7R5J 7R5K	5IJN 5IJO 7MW0 7MW1 7PER 7R5J 7R5K
Enriched GO Terms of Interacting Partners?		Nuclear Pore Organization Structural Constituent Of Nuclear Pore Nucleus Organization Nuclear Pore Import Into Nucleus MRNA Transport Protein Import Into Nucleus Nuclear Pore Complex Assembly Nuclear Pore Nuclear Basket RNA Transport Nuclear Periphery Protein Localization To Nucleus Pore Complex Assembly Nucleobase-containing Compound Transport Nuclear Envelope Nuclear Transport Nucleocytoplasmic Transport Nuclear Membrane Establishment Of Protein Localization To Organelle RNA Export From Nucleus Telomere Tethering At Nuclear Periphery Intracellular Protein Transport Activating MHC Class I Receptor Activity Negative Regulation Of CD4-positive, Alpha-beta T Cell Costimulation Protein Localization To Organelle Nuclear Export Negative Regulation Of Adaptive Immune Memory Response Post-transcriptional Tethering Of RNA Polymerase II Gene DNA At Nuclear Periphery Negative Regulation Of T Cell Costimulation Nuclear Pore Cytoplasmic Filaments MHC Class I Receptor Activity Positive Regulation Of Natural Killer Cell Degranulation Positive Regulation Of Natural Killer Cell Mediated Immune Response To Tumor Cell MHC Class Ib Receptor Activity Nuclear Pore Central Transport Channel Spinal Cord Motor Neuron Cell Fate Specification Transcription-dependent Tethering Of RNA Polymerase II Gene DNA At Nuclear Periphery MHC Class I Protein Complex Binding Protein Transport Telomere Localization Positive Regulation Of Natural Killer Cell Cytokine Production Nuclear Pore Outer Ring Intracellular Transport Regulation Of Natural Killer Cell Cytokine Production Nuclear Inclusion Body Establishment Of Protein Localization Nuclear Body Protein-containing Complex Organization Positive Regulation Of Immune Response To Tumor Cell Cellular Localization	Nuclear Pore Organization Structural Constituent Of Nuclear Pore Nucleus Organization Nuclear Pore Complex Assembly Nuclear Pore Pore Complex Assembly MRNA Transport RNA Transport Nucleobase-containing Compound Transport Nuclear Envelope Nuclear Transport Nucleocytoplasmic Transport Nuclear Membrane RNA Polymerase I Transcription Regulatory Region Sequence-specific DNA Binding Nuclear Pore Transmembrane Ring Response To Vitamin B2 C/EBP Complex AP-5 Adaptor Complex GMP Binding CHOP-C/EBP Complex Positive Regulation Of Mitochondrial RNA Catabolic Process Nuclear Pore Inner Ring Notch Signaling Pathway White Fat Cell Proliferation Phosphatidylethanolamine Catabolic Process Protein Transport Arterial Endothelial Cell Differentiation Negative Regulation Of Hematopoietic Stem Cell Proliferation Rb-E2F Complex Cardiolipin Acyl-chain Remodeling AP-type Membrane Coat Adaptor Complex Nuclear Pore Localization
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