GRAMD4 and PKDREJ

		GRAMD4	PKDREJ
Description		GRAM domain containing 4	polycystin family receptor for egg jelly
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Mitochondrion Endoplasmic Reticulum Endoplasmic Reticulum Membrane Membrane Mitochondrial Membrane	Acrosomal Membrane Nucleus Plasma Membrane Membrane Cytoplasmic Vesicle Sperm Plasma Membrane
	Molecular Function	Protein Binding	Calcium Channel Activity Calcium Ion Binding
	Biological Process	Apoptotic Process Negative Regulation Of Toll-like Receptor 9 Signaling Pathway Positive Regulation Of Apoptotic Process	Acrosome Reaction Detection Of Mechanical Stimulus Regulation Of Acrosome Reaction Calcium Ion Transmembrane Transport
Pathways
Drugs
Diseases
GWAS		Urate levels in obese individuals ( 25811787)
Interacting Genes		13 interacting genes: APP CATSPERT CCDC146 EXOC8 FAM9B GADD45G MTMR9 NTAQ1 PLEKHF2 RBL2 SH2D4A SMARCD1 TACC2	2 interacting genes: LNX1 LNX2
Entrez ID		23151	10343
HPRD ID		11107	05239
Ensembl ID		ENSG00000075240	ENSG00000130943
Uniprot IDs		Q6IC98	Q9NTG1
PDB IDs
Enriched GO Terms of Interacting Partners?			PDZ Domain Binding Negative Regulation Of Toll-like Receptor 9 Signaling Pathway Ubiquitin-protein Transferase Activity Regulation Of Toll-like Receptor 9 Signaling Pathway Nervous System Development Synapse Maturation
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