MRPS27 and SNRNP48

Number of citations of the paper that reports this interaction (PubMedID 34133714)
84

Data Source:
BioGRID (two hybrid)

		MRPS27	SNRNP48
Description		mitochondrial ribosomal protein S27	small nuclear ribonucleoprotein U11/U12 subunit 48
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GO Annotations	Cellular Component	Nucleolus Cytoplasm Mitochondrion Mitochondrial Inner Membrane Mitochondrial Small Ribosomal Subunit Ribosome Ribonucleoprotein Complex	Nucleus Nucleoplasm Spliceosomal Complex U12-type Spliceosomal Complex Cytosol
	Molecular Function	TRNA Binding RNA Binding Protein Binding RRNA Binding	Protein Binding Zinc Ion Binding Metal Ion Binding
	Biological Process	Regulation Of Translation Cell Population Proliferation Mitochondrial Translation	MRNA Processing RNA Splicing
Pathways		Mitochondrial translation initiation Mitochondrial translation elongation Mitochondrial translation elongation Mitochondrial translation termination Mitochondrial ribosome-associated quality control	mRNA Splicing - Minor Pathway
Drugs
Diseases
GWAS		Refractive error ( 32231278)	BMI x environmental factors (excluding physical activity) interaction ( 33654129) BMI x environmental factors (including physical activity) interaction ( 33654129) Height ( 31562340) Obesity-related traits ( 23251661)
Interacting Genes		5 interacting genes: CFTR NECAB2 PTEN SNRNP48 YWHAQ	14 interacting genes: CDCA7L ENKD1 EXOSC7 GPX4 GRN HUNK LUC7L2 MRPS27 PRPF6 SRSF8 SUPT5H TFIP11 UBASH3A UTP14A
Entrez ID		23107	154007
HPRD ID		17596	12858
Ensembl ID		ENSG00000113048	ENSG00000168566
Uniprot IDs		G5EA06 Q6PKB3 Q92552	Q6IEG0
PDB IDs		3J9M 6NU2 6NU3 6RW4 6RW5 6VLZ 6VMI 6ZM5 6ZM6 6ZS9 6ZSA 6ZSB 6ZSC 6ZSD 6ZSE 6ZSG 7A5F 7A5G 7A5I 7A5K 7L08 7OG4 7P2E 7PNX 7PNY 7PNZ 7PO0 7PO1 7PO2 7PO3 7QI4 7QI5 7QI6 8ANY 8CSP 8CSQ 8CSR 8CSS 8CST 8CSU 8K2A 8OIR 8OIS 8QRK 8QRL 8QRM 8QRN 8RRI 8XT0 8XT2	2VY4 2VY5 8R7N 8Y6O 9GBW 9GC0 9GCL
Enriched GO Terms of Interacting Partners?		Negative Regulation Of Transport 14-3-3 Protein Binding Regulation Of Transport Positive Regulation Of Anion Channel Activity Intracellularly ATP-gated Chloride Channel Activity Positive Regulation Of Voltage-gated Chloride Channel Activity Sec61 Translocon Complex Binding PDZ Domain Binding Negative Regulation Of Synaptic Vesicle Clustering Phosphatidylinositol-3,4-bisphosphate 3-phosphatase Activity Negative Regulation Of Keratinocyte Migration Inositol-1,3,4,5-tetrakisphosphate 3-phosphatase Activity Synapse Inositol-1,3,4,5,6-pentakisphosphate 3-phosphatase Activity Somatostatin Secretion Positive Regulation Of Epinephrine Secretion Negative Regulation Of G Protein-coupled Receptor Internalization Positive Regulation Of Monoatomic Anion Transport Central Nervous System Myelin Maintenance Circadian Rhythm Rhythmic Synaptic Transmission Regulation Of Nervous System Process Negative Regulation Of Glucagon Secretion Positive Regulation Of Adenosine Receptor Signaling Pathway A2A Adenosine Receptor Binding Positive Regulation Of Enamel Mineralization Adult Behavior Negative Regulation Of Wound Healing, Spreading Of Epidermal Cells Type 5 Metabotropic Glutamate Receptor Binding Regulation Of Insulin Secretion Transepithelial Water Transport Phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase Activity Myelin Sheath Adaxonal Region Phosphatidylinositol Phosphate Phosphatase Activity Regulation Of Peptide Hormone Secretion Positive Regulation Of Tooth Mineralization Chloride Channel Inhibitor Activity Chloride Channel Regulator Activity Regulation Of Enamel Mineralization Membrane Hyperpolarization Negative Regulation Of Peptidyl-serine Phosphorylation Regulation Of Synaptic Vesicle Clustering Postsynaptic Density Assembly Positive Regulation Of Transmission Of Nerve Impulse Regulation Of Glucagon Secretion Developmental Maturation Identical Protein Binding Bicarbonate Transmembrane Transporter Activity Positive Regulation Of Cell Communication Intracellular PH Elevation	RNA Binding Nuclear Speck
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