ERO1A and PDILT

Number of citations of the paper that reports this interaction (PubMedID 15475357)
0

Data Source:
HPRD (in vitro, in vivo)

		ERO1A	PDILT
Description		endoplasmic reticulum oxidoreductase 1 alpha	protein disulfide isomerase like, testis expressed
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GO Annotations	Cellular Component	Extracellular Region Extracellular Space Endoplasmic Reticulum Endoplasmic Reticulum Lumen Endoplasmic Reticulum Membrane Golgi Apparatus Golgi Lumen Membrane Dendrite Cell Projection Intracellular Membrane-bounded Organelle	Endoplasmic Reticulum
	Molecular Function	Protein Binding Protein-disulfide Reductase Activity Oxidoreductase Activity Thiol Oxidase Activity FAD Binding	Protein Disulfide Isomerase Activity Isomerase Activity Protein Folding Chaperone
	Biological Process	Protein Folding Apoptotic Process Response To Oxidative Stress Transforming Growth Factor Beta Receptor Signaling Pathway Skeletal Muscle Tissue Development Response To Temperature Stimulus L-ascorbic Acid Metabolic Process Extracellular Matrix Organization Collagen Fibril Organization Endoplasmic Reticulum Unfolded Protein Response Protein Folding In Endoplasmic Reticulum Response To Endoplasmic Reticulum Stress Protein Modification Process Cell Redox Homeostasis Brown Fat Cell Differentiation Release Of Sequestered Calcium Ion Into Cytosol Protein Maturation Intrinsic Apoptotic Signaling Pathway In Response To Endoplasmic Reticulum Stress Cellular Response To Hypoxia	Protein Folding Spermatogenesis Spermatid Development Germ Cell Migration Cell Differentiation
Pathways		Detoxification of Reactive Oxygen Species
Drugs
Diseases
GWAS		Heel bone mineral density ( 30598549) Urine 6-bromotryptophan levels in chronic kidney disease ( 32572055)	Adult body size ( 32376654) Blood urea nitrogen levels ( 29403010 31152163) Body mass index ( 29273807) Chronic kidney disease ( 31152163 20383146) Creatinine levels ( 29403010 31015462) Diastolic blood pressure ( 27841878) Diastolic blood pressure x smoking status (ever vs never) interaction (1df test) ( 29455858) Diastolic blood pressure x smoking status (ever vs never) interaction (2df test) ( 29455858) Estimated glomerular filtration rate ( 31451708 31152163 30604766) Estimated glomerular filtration rate (creatinine, CKDi25) ( 33137338) Estimated glomerular filtration rate (creatinine, Rapid3) ( 33137338) Estimated glomerular filtration rate in diabetes ( 31451708) Estimated glomerular filtration rate in non-diabetics ( 31451708) Glomerular filtration rate ( 29403010 27588450) Kidney function decline traits ( 25493955) Kidney volume ( 34128465) Medication use (agents acting on the renin-angiotensin system) ( 31015401) Medication use (beta blocking agents) ( 31015401) Medication use (diuretics) ( 31015401) Urate levels ( 31578528) Urinary uromodulin levels ( 24578125) Urolithiasis ( 30975718)
Interacting Genes		14 interacting genes: APPBP2 EBF1 ERP44 GPX7 GPX8 GRSF1 LHX4 LINC01554 OGT P4HB PDIA3 PDILT PELI2 RHOU	1 interacting genes: ERO1A
Entrez ID		30001	204474
HPRD ID		13278	15111
Ensembl ID		ENSG00000197930	ENSG00000169340
Uniprot IDs		Q96HE7	Q8N807
PDB IDs		3AHQ 3AHR	4NWY 5XF7
Enriched GO Terms of Interacting Partners?		Protein Disulfide Isomerase Activity Endoplasmic Reticulum Lumen Protein Folding Protein Folding In Endoplasmic Reticulum Cellular Response To Interleukin-7 Response To Interleukin-7 Cul2-RING Ubiquitin Ligase Complex Glutathione Peroxidase Activity Protein-disulfide Reductase Activity Peroxidase Activity Isomerase Activity Transport Of Viral Material Towards Nucleus Microtubule-dependent Intracellular Transport Of Viral Material Towards Nucleus Protein N-acetylglucosaminyltransferase Complex Negative Regulation Of Non-canonical Inflammasome Complex Assembly Response To Endoplasmic Reticulum Stress	L-ascorbic Acid Metabolic Process Thiol Oxidase Activity Protein Folding In Endoplasmic Reticulum Brown Fat Cell Differentiation Cell Redox Homeostasis Intrinsic Apoptotic Signaling Pathway In Response To Endoplasmic Reticulum Stress Protein-disulfide Reductase Activity FAD Binding Skeletal Muscle Tissue Development Collagen Fibril Organization Release Of Sequestered Calcium Ion Into Cytosol Endoplasmic Reticulum Unfolded Protein Response Negative Regulation Of Sequestering Of Calcium Ion Golgi Lumen Calcium Ion Transmembrane Import Into Cytosol Transforming Growth Factor Beta Receptor Signaling Pathway Cellular Response To Decreased Oxygen Levels Striated Muscle Tissue Development Regulation Of Sequestering Of Calcium Ion Intracellular Membrane-bounded Organelle Fat Cell Differentiation Cellular Response To Hypoxia Muscle Tissue Development Response To Temperature Stimulus Cellular Response To Oxygen Levels Monosaccharide Metabolic Process Transforming Growth Factor Beta Receptor Superfamily Signaling Pathway Intrinsic Apoptotic Signaling Pathway Cell Surface Receptor Protein Serine/threonine Kinase Signaling Pathway Calcium Ion Transmembrane Transport Protein Folding Extracellular Matrix Organization Response To Endoplasmic Reticulum Stress Extracellular Structure Organization Calcium Ion Transport Response To Hypoxia Endoplasmic Reticulum Lumen Protein Maturation Response To Decreased Oxygen Levels Apoptotic Signaling Pathway Response To Oxygen Levels
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