WDTC1 and MED23

Number of citations of the paper that reports this interaction (PMID 12421765)
28

Data Source:
HPRD (two hybrid)

		WDTC1	MED23
Gene Name		WD and tetratricopeptide repeats 1	mediator complex subunit 23
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Cytosol	Nucleoplasm Transcription Factor Complex Mediator Complex
	Molecular Function	Enzyme Inhibitor Activity Protein Binding Histone Binding Histone Deacetylase Binding	Transcription Coactivator Activity Protein Binding
	Biological Process	Negative Regulation Of Transcription From RNA Polymerase II Promoter In Utero Embryonic Development Glucose Metabolic Process Regulation Of Cell Size Protein Ubiquitination Cellular Response To Insulin Stimulus Multicellular Organism Growth Negative Regulation Of Catalytic Activity Negative Regulation Of Fatty Acid Biosynthetic Process Cellular Chemical Homeostasis	Regulation Of Transcription, DNA-templated Regulation Of Transcription From RNA Polymerase II Promoter Transcription Initiation From RNA Polymerase II Promoter Gene Expression
Pathways			PPARA activates gene expression Fatty acid, triacylglycerol, and ketone body metabolism Metabolism of lipids and lipoproteins Generic Transcription Pathway Transcriptional regulation of white adipocyte differentiation Regulation of lipid metabolism by Peroxisome proliferator-activated receptor alpha (PPARalpha)
Drugs
Diseases
GWAS
Protein-Protein Interactions		3 interactors: DDB1 MED23 MED4	14 interactors: CEBPB CTDP1 ELF3 ESR1 ESR2 ETS1 FOXJ3 MED13 MED9 NCOA6 PUM2 RELA SREBF1 WDTC1
Entrez ID		23038	9439
HPRD ID		10307	05436
Ensembl ID		ENSG00000142784	ENSG00000112282
Uniprot IDs		Q8N5D0	Q05DL5 Q9ULK4
PDB IDs		3I7N
Enriched GO Terms of Interacting Partners?		Transcription Initiation From RNA Polymerase II Promoter DNA-templated Transcription, Initiation Positive Regulation By Virus Of Viral Protein Levels In Host Cell UV-damage Excision Repair Positive Regulation Of Viral Release From Host Cell Histone H2A Monoubiquitination Histone H2A Ubiquitination Nucleotide-excision Repair, DNA Damage Removal Histone Monoubiquitination Positive Regulation Of Viral Genome Replication Regulation Of Viral Release From Host Cell Transcription From RNA Polymerase II Promoter Interaction With Symbiont Histone Ubiquitination Androgen Receptor Signaling Pathway Protein Monoubiquitination Nucleobase-containing Compound Metabolic Process Protein Ubiquitination Involved In Ubiquitin-dependent Protein Catabolic Process Cellular Response To UV Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Regulation Of Viral Genome Replication Positive Regulation Of Viral Process Intracellular Steroid Hormone Receptor Signaling Pathway Cellular Nitrogen Compound Metabolic Process	Transcription From RNA Polymerase II Promoter Regulation Of Transcription From RNA Polymerase II Promoter Transcription, DNA-templated RNA Biosynthetic Process Regulation Of Gene Expression RNA Metabolic Process Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Gene Expression Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Regulation Of Nitrogen Compound Metabolic Process Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Gene Expression Positive Regulation Of Cellular Biosynthetic Process Intracellular Receptor Signaling Pathway Intracellular Steroid Hormone Receptor Signaling Pathway Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of Metabolic Process Intracellular Estrogen Receptor Signaling Pathway Nucleobase-containing Compound Metabolic Process Positive Regulation Of Transcription, DNA-templated Gland Development Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Biosynthetic Process Response To Hormone Cellular Nitrogen Compound Metabolic Process Nitrogen Compound Metabolic Process Transcription Initiation From RNA Polymerase II Promoter Positive Regulation Of Cellular Metabolic Process Negative Regulation Of Gene Expression Response To Lipid Response To Steroid Hormone DNA-templated Transcription, Initiation Cellular Response To Hormone Stimulus Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Positive Regulation Of Metabolic Process Response To Organic Substance Vagina Development Uterus Development Negative Regulation Of Biosynthetic Process Regulation Of Cellular Process Female Genitalia Development Mammary Gland Epithelial Cell Proliferation Cellular Response To Lipid
Tagcloud ?		a8 abcc5 acvr2 biallelic crcs driver frameshift g8 glyr1 harbored intronic know microsatellite mismatch mononucleotide msh3 msi or51e2 passengers repeats rock1 suppressors t8 t9 tceb3 tgfbr2 tumourigenesis unbiased whenever	acetyltransferases ad5 adenovirus capable cbp compete cr3 cr3s dramatic e1a expanded experimentally hsug1 largest mediator modeled modest pcaf prototype representative s8 squelching sug1 suggestive tata tbp transactivation unidentified v147l
Tagcloud (Difference) ?		a8 abcc5 acvr2 biallelic crcs driver frameshift g8 glyr1 harbored intronic know microsatellite mismatch mononucleotide msh3 msi or51e2 passengers repeats rock1 suppressors t8 t9 tceb3 tgfbr2 tumourigenesis unbiased whenever	acetyltransferases ad5 adenovirus capable cbp compete cr3 cr3s dramatic e1a expanded experimentally hsug1 largest mediator modeled modest pcaf prototype representative s8 squelching sug1 suggestive tata tbp transactivation unidentified v147l
Tagcloud (Intersection) ?