SMNDC1 and SNRNP200

Number of citations of the paper that reports this interaction (PMID 11331595)
10

Data Source:
BioGRID (affinity chromatography technology)
HPRD (in vitro)

		SMNDC1	SNRNP200
Gene Name		survival motor neuron domain containing 1	small nuclear ribonucleoprotein 200kDa (U5)
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Gene Ontology Annotations	Cellular Component	Nucleus Nucleoplasm Spliceosomal Complex Cytoplasm Cajal Body Nuclear Speck Intermediate Filament Cytoskeleton	Nucleus Nucleoplasm Spliceosomal Complex U5 SnRNP Membrane Catalytic Step 2 Spliceosome
	Molecular Function	Protein Binding Poly(A) RNA Binding	ATP-dependent RNA Helicase Activity Protein Binding ATP Binding ATP-dependent Helicase Activity Identical Protein Binding Poly(A) RNA Binding
	Biological Process	Spliceosomal Complex Assembly RNA Splicing, Via Transesterification Reactions MRNA Processing Apoptotic Process RNA Splicing	Cis Assembly Of Pre-catalytic Spliceosome MRNA Splicing, Via Spliceosome Osteoblast Differentiation RNA Splicing Gene Expression
Pathways			Processing of Capped Intron-Containing Pre-mRNA mRNA Splicing mRNA Splicing - Minor Pathway mRNA Splicing - Major Pathway
Drugs
Diseases
GWAS
Protein-Protein Interactions		4 interactors: HIST3H3 KPNB1 SNRNP200 SNRPB	19 interactors: APC BARD1 BRCA1 CHMP1B ECT2 ERG GRB2 LSM8 MEGF10 PIN1 PRPF8 RNF113A SART1 SF3B2 SMNDC1 SNRNP40 USP19 YWHAB YWHAG
Entrez ID		10285	23020
HPRD ID		04627	03391
Ensembl ID			ENSG00000144028
Uniprot IDs		O75940	O75643
PDB IDs		4A4F 4A4H	2Q0Z 4F91 4F92 4F93 4KIT
Enriched GO Terms of Interacting Partners?		Ribonucleoprotein Complex Assembly Cis Assembly Of Pre-catalytic Spliceosome MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions Ribonucleoprotein Complex Biogenesis Ribosomal Protein Import Into Nucleus RNA Splicing Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process MRNA Processing Cellular Nitrogen Compound Metabolic Process MRNA Cis Splicing, Via Spliceosome MRNA Metabolic Process Nitrogen Compound Metabolic Process Apoptotic DNA Fragmentation RNA Processing NLS-bearing Protein Import Into Nucleus Histone MRNA Metabolic Process Cellular Macromolecular Complex Assembly Intracellular Transport Of Virus Protein Import Into Nucleus, Translocation Apoptotic Nuclear Changes Termination Of RNA Polymerase II Transcription Spliceosomal SnRNP Assembly Cellular Component Disassembly Involved In Execution Phase Of Apoptosis Spliceosomal Complex Assembly DNA Metabolic Process DNA-templated Transcription, Termination Execution Phase Of Apoptosis Telomere Maintenance MRNA 3'-end Processing DNA Catabolic Process, Endonucleolytic RNA 3'-end Processing	MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions Regulation Of Organelle Organization RNA Splicing Regulation Of Cell Cycle MRNA Processing Regulation Of Cell Cycle Process MRNA Metabolic Process Cell Cycle RNA Processing Regulation Of Microtubule Cytoskeleton Organization Apoptotic Process Apoptotic Signaling Pathway Programmed Cell Death Cell Cycle Process Regulation Of Microtubule-based Process Cell Death Death Positive Regulation Of Organelle Organization Intrinsic Apoptotic Signaling Pathway Protein K6-linked Ubiquitination Regulation Of Cytoskeleton Organization Regulation Of Phosphorylation Regulation Of Cell Division Regulation Of Cellular Component Organization Cytokinesis Positive Regulation Of Apoptotic Process Regulation Of Phosphorus Metabolic Process Positive Regulation Of Programmed Cell Death Positive Regulation Of Cell Death Regulation Of Protein Metabolic Process Regulation Of Mitotic Nuclear Division Regulation Of Attachment Of Spindle Microtubules To Kinetochore Positive Regulation Of Protein Insertion Into Mitochondrial Membrane Involved In Apoptotic Signaling Pathway Cell Cycle Arrest Response To Ionizing Radiation Positive Regulation Of Protein Metabolic Process Positive Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway Regulation Of Protein Localization Intracellular Signal Transduction Regulation Of Intracellular Transport Cellular Component Assembly Ribonucleoprotein Complex Assembly Negative Regulation Of Cell Cycle Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway Regulation Of Cellular Protein Metabolic Process Cellular Response To Organonitrogen Compound Spliceosomal SnRNP Assembly Regulation Of Apoptotic Process Regulation Of Centrosome Duplication
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