WDR47 and TCL1A

Number of citations of the paper that reports this interaction (PubMedID 25416956)
56

Data Source:
BioGRID (two hybrid)

		WDR47	TCL1A
Description		WD repeat domain 47	TCL1 family AKT coactivator A
Image		No pdb structure
GO Annotations	Cellular Component	Cytoplasm Cytoskeleton Microtubule Axon Dendrite Growth Cone Neuron Projection Neuronal Cell Body	Nucleus Nucleoplasm Cytoplasm Endoplasmic Reticulum Cytosol
	Molecular Function	Protein Binding	Protein Binding Protein Kinase Binding Identical Protein Binding Protein Serine/threonine Kinase Activator Activity
	Biological Process	Microtubule Cytoskeleton Organization Autophagy Negative Regulation Of Microtubule Depolymerization Brain Development Locomotory Behavior Adult Locomotory Behavior Cerebral Cortex Radial Glia-guided Migration Anterior Commissure Morphogenesis Cerebral Cortex Development Corpus Callosum Development Neuron Projection Development Neural Precursor Cell Proliferation Motor Behavior Neuronal Stem Cell Population Maintenance Detection Of Hot Stimulus Involved In Thermoception	Intracellular Signal Transduction
Pathways
Drugs
Diseases
GWAS			Adverse response to aromatase inhibitors ( 20876420) Mosaic loss of chromosome Y ( 27064253) Mosaic loss of chromosome Y (Y chromosome dosage) ( 28346444 31624269) Plateletcrit ( 32888494) Refractive error ( 32231278)
Interacting Genes		6 interacting genes: CHFR DSCR9 FAM107A TCEA2 TCL1A USP21	37 interacting genes: AKT1 AKT2 AKT3 ATM CADPS CALCOCO2 CARD9 CASP8AP2 CCDC13 CEP55 DDIT4L FLACC1 GOLGA2 H2AC25 INCA1 LNX1 LNX2 LSM3 NFKBIA NFKBID NIF3L1 NTAQ1 PPP1R13B PRTFDC1 REL TAX1BP1 TCF4 TEPSIN TNKS TP53BP2 TRAF1 TRAF2 TRMT61A TTC33 TXLNA TXLNB WDR47
Entrez ID		22911	8115
HPRD ID		15670	01744
Ensembl ID		ENSG00000085433	ENSG00000100721
Uniprot IDs		O94967	P56279
PDB IDs			1JSG
Enriched GO Terms of Interacting Partners?			Negative Regulation Of PERK-mediated Unfolded Protein Response Regulation Of PERK-mediated Unfolded Protein Response Apoptotic Signaling Pathway Identical Protein Binding Negative Regulation Of Endoplasmic Reticulum Unfolded Protein Response Negative Regulation Of Long-chain Fatty Acid Import Across Plasma Membrane Cytoplasm Signaling Adaptor Activity Non-canonical NF-kappaB Signal Transduction Regulation Of Endoplasmic Reticulum Unfolded Protein Response Regulation Of Canonical NF-kappaB Signal Transduction Apoptotic Process Toll-like Receptor 4 Signaling Pathway Peptidyl-serine Phosphorylation Negative Regulation Of Fatty Acid Transport Programmed Cell Death Regulation Of Long-chain Fatty Acid Import Into Cell Peripheral Nervous System Myelin Maintenance Cell Death Cell Surface Toll-like Receptor Signaling Pathway Negative Regulation Of Lipid Transport Protein Binding Regulation Of Apoptotic Process Negative Regulation Of Response To Endoplasmic Reticulum Stress Syntaxin Binding Regulation Of Programmed Cell Death Thioesterase Binding Cell Surface Pattern Recognition Receptor Signaling Pathway Tumor Necrosis Factor-mediated Signaling Pathway Protein Polyubiquitination Positive Regulation Of Blood Vessel Endothelial Cell Migration Regulation Of Telomere Capping Myelin Maintenance Innate Immune Response Activating Cell Surface Receptor Signaling Pathway Intrinsic Apoptotic Signaling Pathway Mammary Gland Epithelial Cell Differentiation Glycogen Biosynthetic Process Regulation Of Fatty Acid Beta-oxidation Positive Regulation Of Glycogen Biosynthetic Process Insulin Receptor Signaling Pathway Regulation Of DNA-binding Transcription Factor Activity Positive Regulation Of NF-kappaB Transcription Factor Activity Positive Regulation Of T-helper 17 Type Immune Response Negative Regulation Of Cell Cycle Response To Muramyl Dipeptide Intracellular Signal Transduction Peptidyl-threonine Phosphorylation Regulation Of Response To Endoplasmic Reticulum Stress Polysaccharide Biosynthetic Process Positive Regulation Of Telomere Maintenance Via Telomerase
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