BAHD1 and FBXO11

Number of citations of the paper that reports this interaction (PubMedID 33156908)
60

Data Source:
BioGRID (enzymatic study)

		BAHD1	FBXO11
Description		bromo adjacent homology domain containing 1	F-box protein 11
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Chromatin Silencing Complex Chromosome	Ubiquitin Ligase Complex Nucleus Nucleoplasm Chromosome Nucleolus Cytoplasm Cytosol
	Molecular Function	Transcription Cis-regulatory Region Binding Chromatin Binding Protein Binding	Ubiquitin-protein Transferase Activity Protein Binding Zinc Ion Binding Protein-arginine N-methyltransferase Activity Metal Ion Binding Ubiquitin-like Ligase-substrate Adaptor Activity
	Biological Process	Chromatin Organization Heterochromatin Formation Negative Regulation Of DNA-templated Transcription	Epithelial To Mesenchymal Transition Ubiquitin-dependent Protein Catabolic Process Sensory Perception Of Sound Negative Regulation Of Epithelial To Mesenchymal Transition Protein Ubiquitination Regulation Of Apoptotic Process Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process
Pathways			Neddylation Antigen processing: Ubiquitination & Proteasome degradation
Drugs
Diseases
GWAS		HDL cholesterol levels ( 32203549) Malaria ( 31844061) Mean reticulocyte volume ( 32888494) Refractive error ( 32231278)	Appendicular lean mass ( 33097823) Aspartate aminotransferase levels ( 33547301) Asthma ( 27611488) Chronotype ( 30696823) Cortical surface area ( 32963231) Itch intensity from mosquito bite ( 28199695) Itch intensity from mosquito bite adjusted by bite size ( 28199695) Macular thickness ( 30535121) PR interval ( 32439900) Refractive error ( 32231278) Schizophrenia ( 23894747)
Interacting Genes		49 interacting genes: ARID5A BACH2 BEGAIN CALCOCO2 CARD10 CBX1 CYSRT1 DVL2 DVL3 FBXO11 GOLGA2 GOLGA6L9 HOXA1 KDM1A KHDRBS2 KHDRBS3 KPNA3 KRT40 KRTAP10-1 KRTAP10-3 KRTAP10-7 KRTAP10-8 KRTAP19-1 KRTAP19-7 KRTAP2-3 KRTAP2-4 KRTAP4-12 KRTAP6-1 LASP1 LZTS2 M1AP MDFI MEGF10 MID2 PICK1 PRDM14 PRKAR1A RBM10 SUV39H1 TLE5 TNS2 TRAF2 TRAF4 ZNF275 ZNF317 ZNF408 ZNF526 ZNF837 ZRANB1	8 interacting genes: BAHD1 BCL6 CFTR DSCR9 HDAC6 HNRNPA2B1 TP53 USP16
Entrez ID		22893	80204
HPRD ID		12518	06985
Ensembl ID		ENSG00000140320	ENSG00000138081
Uniprot IDs		Q8TBE0	A0A804HK63 Q86XK2
PDB IDs			5VMD
Enriched GO Terms of Interacting Partners?		Intermediate Filament Keratin Filament Identical Protein Binding Regulation Of JNK Cascade Regulation Of RNA Metabolic Process Positive Regulation Of Neuron Projection Arborization Zinc Ion Binding Muscle Cell Proliferation Thioesterase Binding	Chromatin Remodeling Epigenetic Regulation Of Gene Expression Chromatin Organization Negative Regulation Of Cell Growth Negative Regulation Of DNA Replication Negative Regulation Of Gene Expression, Epigenetic Replication Fork 14-3-3 Protein Binding Negative Regulation Of Growth Negative Regulation Of Macroautophagy Negative Regulation Of Reactive Oxygen Species Metabolic Process Regulation Of Cellular Senescence Regulation Of Lymphocyte Apoptotic Process Cellular Response To Stress Transcription Corepressor Binding Negative Regulation Of Mitotic Cell Cycle DNA Replication Negative Regulation Of Cell Development Intracellularly ATP-gated Chloride Channel Activity Positive Regulation Of Voltage-gated Chloride Channel Activity Sec61 Translocon Complex Binding Regulation Of Telomere Maintenance Via Telomere Lengthening Molecular Condensate Scaffold Activity Regulation Of Mitophagy Negative Regulation Of Helicase Activity Regulation Of Autophagy Of Mitochondrion Negative Regulation Of G1 To G0 Transition Mitophagy Polyubiquitinated Misfolded Protein Transport Positive Regulation Of Cholangiocyte Proliferation Positive Regulation Of Ribosome Biogenesis T Cell Activation Involved In Immune Response Autophagy Of Mitochondrion Regulation Of DNA Metabolic Process Negative Regulation Of Isotype Switching To IgE Isotypes Lymphocyte Activation Involved In Immune Response Negative Regulation Of Gene Expression Regulation Of Mitotic Cell Cycle DNA Replication Regulation Of DNA Replication Negative Regulation Of Mast Cell Cytokine Production Isotype Switching To IgE Isotypes Mononuclear Cell Proliferation Regulation Of Cell Growth Chromatin Binding Lymphocyte Proliferation Negative Regulation Of Plasma Cell Differentiation Intronic Transcription Regulatory Region Sequence-specific DNA Binding Protein-folding Chaperone Binding Enzyme Binding Positive Regulation Of Anion Channel Activity Positive Regulation Of Monoatomic Anion Transport
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