ZHX2 and DHRS2

Number of citations of the paper that reports this interaction (PMID 21988832)
14

Data Source:
BioGRID (two hybrid)

		ZHX2	DHRS2
Gene Name		zinc fingers and homeoboxes 2	dehydrogenase/reductase (SDR family) member 2
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Plasma Membrane	Nucleus Nuclear Envelope Cytoplasm Mitochondrion Mitochondrial Matrix Extracellular Vesicular Exosome
	Molecular Function	DNA Binding Sequence-specific DNA Binding Transcription Factor Activity Transcription Corepressor Activity Protein Binding Protein Homodimerization Activity Metal Ion Binding Protein Heterodimerization Activity	Carbonyl Reductase (NADPH) Activity
	Biological Process	Negative Regulation Of Transcription From RNA Polymerase II Promoter Transcription, DNA-templated MRNA Catabolic Process Somatic Stem Cell Maintenance Negative Regulation Of Neuron Differentiation Negative Regulation Of Transcription, DNA-templated	C21-steroid Hormone Metabolic Process Negative Regulation Of Cell Proliferation Response To Toxic Substance Cellular Response To Oxidative Stress Myeloid Dendritic Cell Differentiation Negative Regulation Of Apoptotic Process Oxidation-reduction Process
Pathways
Drugs
Diseases
GWAS		Carotid intima media thickness ( 21909108) Immune response to smallpox vaccine (IL-6) ( 22542470)
Protein-Protein Interactions		9 interactors: APP ATXN1 DHRS2 LAT NAGPA NFYA YWHAQ ZHX1 ZHX3	4 interactors: APPBP2 EXOSC5 TCEA2 ZHX2
Entrez ID		22882	10202
HPRD ID		16458	07483
Ensembl ID		ENSG00000178764	ENSG00000100867
Uniprot IDs		Q9Y6X8	Q13268
PDB IDs		2DMP 3NAU
Enriched GO Terms of Interacting Partners?		Intracellular Transport Visual Learning Regulation Of Transcription From RNA Polymerase II Promoter Visual Behavior Establishment Of Localization In Cell Associative Learning Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Cellular Metabolic Process Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Gene Expression Synaptic Growth At Neuromuscular Junction Adult Locomotory Behavior Negative Regulation Of Gene Expression Cellular Localization Negative Regulation Of Biosynthetic Process Collateral Sprouting In Absence Of Injury Learning Cell Activation Adult Behavior Regulation Of Transcription, DNA-templated Collateral Sprouting Axon Midline Choice Point Recognition Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Smooth Endoplasmic Reticulum Calcium Ion Homeostasis Platelet Activation Negative Regulation Of Transcription From RNA Polymerase II Promoter Axon Choice Point Recognition Negative Regulation Of Insulin-like Growth Factor Receptor Signaling Pathway Locomotory Behavior RNA Metabolic Process Neuron Remodeling Regulation Of Gene Expression Regulation Of Nitrogen Compound Metabolic Process Steroid Metabolic Process Learning Or Memory Protein Targeting To Lysosome Cognition Positive Regulation Of Transcription From RNA Polymerase II Promoter Protein Localization To Lysosome Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Developmental Process Response To Light Stimulus Exocytosis Cellular Copper Ion Homeostasis Transcription, DNA-templated RNA Biosynthetic Process	MRNA Catabolic Process RNA Catabolic Process DNA Deamination Aromatic Compound Catabolic Process MRNA Metabolic Process
Tagcloud ?		adm cddp chemotherapeutic chemotherapeutics chip clarify consistently efflux eliminated enhances fingers greatly hcc hepatocellular hepg2 homeoboxes interacted inverse luciferase mdr1 multidrug mutating myeloma repress repressed represses repression y ya
Tagcloud (Difference) ?		adm cddp chemotherapeutic chemotherapeutics chip clarify consistently efflux eliminated enhances fingers greatly hcc hepatocellular hepg2 homeoboxes interacted inverse luciferase mdr1 multidrug mutating myeloma repress repressed represses repression y ya
Tagcloud (Intersection) ?