TUBGCP3 and PROZ

		TUBGCP3	PROZ
Description		tubulin gamma complex component 3	protein Z, vitamin K dependent plasma glycoprotein
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GO Annotations	Cellular Component	Spindle Pole Gamma-tubulin Complex Cytoplasm Centrosome Centriole Microtubule Organizing Center Spindle Polar Microtubule Cytosol Cytoskeleton Microtubule Membrane	Extracellular Region Extracellular Space Endoplasmic Reticulum Lumen Golgi Lumen Extracellular Exosome
	Molecular Function	Structural Molecule Activity Structural Constituent Of Cytoskeleton Protein Binding Gamma-tubulin Binding Microtubule Minus-end Binding	Serine-type Endopeptidase Activity Calcium Ion Binding Protein Binding
	Biological Process	Microtubule Cytoskeleton Organization Mitotic Cell Cycle Microtubule Nucleation Single Fertilization Cytoplasmic Microtubule Organization Spindle Assembly Meiotic Cell Cycle	Proteolysis Blood Coagulation Hemostasis
Pathways		Recruitment of mitotic centrosome proteins and complexes Recruitment of NuMA to mitotic centrosomes	Gamma-carboxylation of protein precursors Transport of gamma-carboxylated protein precursors from the endoplasmic reticulum to the Golgi apparatus Removal of aminoterminal propeptides from gamma-carboxylated proteins
Drugs
Diseases
GWAS		Glycated hemoglobin levels ( 20858683)	Bipolar disorder ( 31043756) Factor VII ( 17903294) Food allergy (parent-of-origin effect) ( 29489655) Reticulocyte fraction of red cells ( 32888494)
Interacting Genes		7 interacting genes: AKAP9 CEBPA DNAJB6 IMMT PCNT TUBG1 TUBG2	1 interacting genes: F2
Entrez ID		10426	8858
HPRD ID		10289	07182
Ensembl ID		ENSG00000126216	ENSG00000126231
Uniprot IDs		A0A087WU06 B4DYP7 Q96CW5	P22891
PDB IDs		6V6B 6V6S 6X0U 7AS4 7QJ0 7QJ1 7QJ2 7QJ3 7QJ4 7QJ5 7QJ6 7QJ7 7QJ8 7QJ9 7QJA 7QJB 7QJC 7QJD 8Q62 8RX1 8VRD 8VRJ 8VRK	3F1S 3H5C
Enriched GO Terms of Interacting Partners?		Microtubule Nucleation Microtubule Nucleator Activity Gamma-tubulin Ring Complex Gamma-tubulin Complex Mitotic Spindle Organization Centrosome Microtubule Cytoskeleton Organization Involved In Mitosis Meiotic Spindle Organization Pericentriolar Material Spindle Organization Microtubule Cytoskeleton Organization Mitotic Sister Chromatid Segregation Cytoskeleton Organization Sister Chromatid Segregation Spindle Microtubule Spindle Organelle Organization Nuclear Chromosome Segregation RNA Polymerase I Transcription Regulatory Region Sequence-specific DNA Binding Cytoplasmic Microtubule Cytoplasmic Microtubule Organization Response To Vitamin B2 C/EBP Complex Microtubule CHOP-C/EBP Complex Microtubule Organizing Center Cytoskeleton Microtubule-based Process Peyer's Patch Morphogenesis Syncytiotrophoblast Cell Differentiation Involved In Labyrinthine Layer Development Chorion Development Dendritic Branch White Fat Cell Proliferation Glial Cell-derived Neurotrophic Factor Receptor Binding	Regulation Of Hormone Secretion Regulation Of Insulin Secretion Regulation Of Protein Secretion Regulation Of Peptide Hormone Secretion Positive Regulation Of Peptide Hormone Secretion Positive Regulation Of Peptide Secretion Positive Regulation Of Phosphatidylinositol 3-kinase/protein Kinase B Signal Transduction Positive Regulation Of Insulin Secretion Thrombospondin Receptor Activity Positive Regulation Of Protein Secretion Positive Regulation Of Protein Transport Positive Regulation Of Hormone Secretion Negative Regulation Of Long-chain Fatty Acid Import Across Plasma Membrane Positive Regulation Of Type B Pancreatic Cell Proliferation Neutrophil-mediated Killing Of Gram-negative Bacterium Regulation Of Phosphatidylinositol 3-kinase/protein Kinase B Signal Transduction Positive Regulation Of Secretion By Cell Polar Microtubule Positive Regulation Of Secretion Positive Regulation Of Establishment Of Protein Localization Positive Regulation Of Phospholipase C-activating G Protein-coupled Receptor Signaling Pathway Phosphatidylinositol 3-kinase Activator Activity Thrombin-activated Receptor Signaling Pathway Neutrophil-mediated Killing Of Bacterium Cytolysis By Host Of Symbiont Cells Positive Regulation Of Protein Localization Regulation Of Protein Transport Positive Regulation Of Fatty Acid Beta-oxidation Negative Regulation Of Fatty Acid Transport Regulation Of Long-chain Fatty Acid Import Into Cell Response To Endothelin Cellular Response To Endothelin Gamma-tubulin Complex Negative Regulation Of Fibrinolysis Regulation Of Type B Pancreatic Cell Proliferation Negative Regulation Of Astrocyte Differentiation Negative Regulation Of B Cell Apoptotic Process Positive Regulation Of Fatty Acid Oxidation Microtubule Minus-end Binding Intracellular Chemical Homeostasis Regulation Of Establishment Of Protein Localization Regulation Of Hormone Levels Regulation Of Fibrinolysis Regulation Of Fatty Acid Beta-oxidation Phosphatidylinositol 3-kinase Binding Positive Regulation Of Glycogen Biosynthetic Process Transmembrane Receptor Protein Tyrosine Kinase Adaptor Activity Negative Regulation Of Platelet Activation Type B Pancreatic Cell Proliferation Regulation Of Secretion By Cell
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