FIGF and ITGA9

Number of citations of the paper that reports this interaction (PMID 15590642)
48

Data Source:
HPRD (in vivo, in vitro)

		FIGF	ITGA9
Gene Name		c-fos induced growth factor (vascular endothelial growth factor D)	integrin, alpha 9
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Extracellular Region Extracellular Space Membrane Platelet Alpha Granule Lumen	Plasma Membrane Integrin Complex Basal Plasma Membrane Integrin Alpha9-beta1 Complex
	Molecular Function	Platelet-derived Growth Factor Receptor Binding Vascular Endothelial Growth Factor Receptor Binding Growth Factor Activity Chemoattractant Activity Protein Homodimerization Activity Vascular Endothelial Growth Factor Receptor 3 Binding	Collagen Binding Laminin Binding Metal Ion Binding
	Biological Process	Angiogenesis Platelet Degranulation Blood Coagulation Cell Proliferation Positive Regulation Of Cell Proliferation Cell Differentiation Platelet Activation Vascular Endothelial Growth Factor Receptor Signaling Pathway Positive Chemotaxis Induction Of Positive Chemotaxis Positive Regulation Of Cell Division Positive Regulation Of Mast Cell Chemotaxis	Cell Adhesion Integrin-mediated Signaling Pathway Axon Guidance Extracellular Matrix Organization Neutrophil Chemotaxis Wound Healing
Pathways		VEGF binds to VEGFR leading to receptor dimerization VEGF ligand-receptor interactions Signaling by VEGF Response to elevated platelet cytosolic Ca2+ Platelet degranulation Platelet activation, signaling and aggregation	Signal transduction by L1 Axon guidance ECM proteoglycans L1CAM interactions Integrin cell surface interactions
Drugs
Diseases
GWAS			Nasopharyngeal carcinoma ( 19478819) Phospholipid levels (plasma) ( 22359512) PR interval ( 23139255)
Protein-Protein Interactions		3 interactors: FLT4 ITGA9 KDR	5 interactors: FIGF ITGB1 PXN SAT1 SPP1
Entrez ID		2277	3680
HPRD ID		02102	04910
Ensembl ID		ENSG00000165197
Uniprot IDs		O43915	Q13797 Q8N6H6
PDB IDs		2XV7
Enriched GO Terms of Interacting Partners?		Lymph Vessel Development Vascular Endothelial Growth Factor Signaling Pathway Cellular Response To Vascular Endothelial Growth Factor Stimulus Sprouting Angiogenesis Positive Regulation Of Endothelial Cell Migration Positive Regulation Of Endothelial Cell Proliferation Positive Regulation Of Epithelial Cell Migration Regulation Of Endothelial Cell Proliferation Vascular Endothelial Growth Factor Receptor Signaling Pathway Regulation Of Endothelial Cell Migration Positive Regulation Of ERK1 And ERK2 Cascade Regulation Of Epithelial Cell Migration Positive Regulation Of Epithelial Cell Proliferation Regulation Of ERK1 And ERK2 Cascade Protein Autophosphorylation Peptidyl-tyrosine Phosphorylation Regulation Of Epithelial Cell Proliferation Regulation Of Blood Vessel Remodeling Positive Regulation Of Cell Migration Angiogenesis Positive Regulation Of Cell Motility Positive Regulation Of Cellular Component Movement Positive Regulation Of Locomotion Extracellular Matrix Organization Extracellular Structure Organization Blood Vessel Morphogenesis Positive Regulation Of MAPK Cascade Anatomical Structure Morphogenesis Positive Regulation Of Protein Kinase C Signaling Lymphangiogenesis Blood Vessel Development Surfactant Homeostasis Vasculature Development Lymph Vessel Morphogenesis Calcium-mediated Signaling Using Intracellular Calcium Source Positive Regulation Of Vasculogenesis Chemical Homeostasis Within A Tissue Positive Regulation Of Nitric-oxide Synthase Biosynthetic Process Cellular Response To Growth Factor Stimulus Regulation Of Cell Migration Response To Growth Factor Regulation Of MAPK Cascade Regulation Of Vasculogenesis Regulation Of Cell Motility Regulation Of Protein Kinase C Signaling Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Cell Surface Receptor Signaling Pathway Regulation Of Locomotion Regulation Of Cellular Component Movement Cell Migration Involved In Sprouting Angiogenesis	Response To Vitamin D Angiogenesis Blood Vessel Morphogenesis Blood Vessel Development Maternal Process Involved In Female Pregnancy Vasculature Development Chemotaxis Response To Vitamin Vascular Endothelial Growth Factor Receptor Signaling Pathway Negative Regulation Of Collateral Sprouting Of Intact Axon In Response To Injury Positive Regulation Of Cell-substrate Adhesion Integrin-mediated Signaling Pathway Negative Regulation Of Cell Projection Organization Multicellular Organismal Development Anatomical Structure Development Regulation Of Collateral Sprouting Of Intact Axon In Response To Injury Spermidine Acetylation Cell-matrix Adhesion Cardiovascular System Development Anatomical Structure Morphogenesis Response To Hormone Putrescine Catabolic Process Regulation Of Collagen Catabolic Process Response To Transforming Growth Factor Beta Negative Regulation Of Neuron Differentiation Regulation Of Cell-substrate Adhesion Cell Junction Assembly Developmental Process Cell-substrate Adhesion Cell-cell Junction Organization Response To Nutrient Positive Regulation Of Mast Cell Chemotaxis Calcium-independent Cell-matrix Adhesion Anatomical Structure Formation Involved In Morphogenesis Leukocyte Migration Female Pregnancy Oxalate Transport Formation Of Radial Glial Scaffolds Cell Adhesion Polyamine Catabolic Process 3'-phosphoadenosine 5'-phosphosulfate Biosynthetic Process Locomotion Negative Regulation Of Collateral Sprouting Negative Regulation Of Neurogenesis Negative Regulation Of Axon Regeneration Cell-cell Adhesion Mediated By Integrin Cellular Response To Stimulus Positive Regulation Of Cell Migration Negative Regulation Of Cell Development Positive Regulation Of Cell Motility
Tagcloud ?		10ng agreed atr bard1 belonged biosynthetic biphenyls brca2 dioxin fancd2 hands immunoblots impulses kcnma1 lactational mycn ndl neurobiological npy4r ontology operator6 pcbs performances projection rad51 scn1a summation transcriptomic validating
Tagcloud (Difference) ?		10ng agreed atr bard1 belonged biosynthetic biphenyls brca2 dioxin fancd2 hands immunoblots impulses kcnma1 lactational mycn ndl neurobiological npy4r ontology operator6 pcbs performances projection rad51 scn1a summation transcriptomic validating
Tagcloud (Intersection) ?