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FIGF
Gene Name
c-fos induced growth factor (vascular endothelial growth factor D)
Image
Gene Ontology Annotations
Cellular Component
Extracellular Region
Extracellular Space
Membrane
Platelet Alpha Granule Lumen
Molecular Function
Platelet-derived Growth Factor Receptor Binding
Vascular Endothelial Growth Factor Receptor Binding
Growth Factor Activity
Chemoattractant Activity
Protein Homodimerization Activity
Vascular Endothelial Growth Factor Receptor 3 Binding
Biological Process
Angiogenesis
Platelet Degranulation
Blood Coagulation
Cell Proliferation
Positive Regulation Of Cell Proliferation
Cell Differentiation
Platelet Activation
Vascular Endothelial Growth Factor Receptor Signaling Pathway
Positive Chemotaxis
Induction Of Positive Chemotaxis
Positive Regulation Of Cell Division
Positive Regulation Of Mast Cell Chemotaxis
Pathways
VEGF binds to VEGFR leading to receptor dimerization
VEGF ligand-receptor interactions
Signaling by VEGF
Response to elevated platelet cytosolic Ca2+
Platelet degranulation
Platelet activation, signaling and aggregation
Drugs
Diseases
GWAS
Protein-protein Interactions
3 interactors:
FLT4
ITGA9
KDR
Entrez ID
2277
HPRD ID
02102
Ensembl ID
ENSG00000165197
Uniprot IDs
O43915
PDB IDs
2XV7
Enriched GO Terms of Interacting Partners
?
Lymph Vessel Development
Vascular Endothelial Growth Factor Signaling Pathway
Cellular Response To Vascular Endothelial Growth Factor Stimulus
Sprouting Angiogenesis
Positive Regulation Of Endothelial Cell Migration
Positive Regulation Of Endothelial Cell Proliferation
Positive Regulation Of Epithelial Cell Migration
Regulation Of Endothelial Cell Proliferation
Vascular Endothelial Growth Factor Receptor Signaling Pathway
Regulation Of Endothelial Cell Migration
Positive Regulation Of ERK1 And ERK2 Cascade
Regulation Of Epithelial Cell Migration
Positive Regulation Of Epithelial Cell Proliferation
Regulation Of ERK1 And ERK2 Cascade
Protein Autophosphorylation
Peptidyl-tyrosine Phosphorylation
Regulation Of Epithelial Cell Proliferation
Regulation Of Blood Vessel Remodeling
Positive Regulation Of Cell Migration
Angiogenesis
Positive Regulation Of Cell Motility
Positive Regulation Of Cellular Component Movement
Positive Regulation Of Locomotion
Extracellular Matrix Organization
Extracellular Structure Organization
Blood Vessel Morphogenesis
Positive Regulation Of MAPK Cascade
Anatomical Structure Morphogenesis
Positive Regulation Of Protein Kinase C Signaling
Lymphangiogenesis
Blood Vessel Development
Surfactant Homeostasis
Vasculature Development
Lymph Vessel Morphogenesis
Calcium-mediated Signaling Using Intracellular Calcium Source
Positive Regulation Of Vasculogenesis
Chemical Homeostasis Within A Tissue
Positive Regulation Of Nitric-oxide Synthase Biosynthetic Process
Cellular Response To Growth Factor Stimulus
Regulation Of Cell Migration
Response To Growth Factor
Regulation Of MAPK Cascade
Regulation Of Vasculogenesis
Regulation Of Cell Motility
Regulation Of Protein Kinase C Signaling
Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway
Cell Surface Receptor Signaling Pathway
Regulation Of Locomotion
Regulation Of Cellular Component Movement
Cell Migration Involved In Sprouting Angiogenesis
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