FGF14 and HOXD12

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		FGF14	HOXD12
Description		fibroblast growth factor 14	homeobox D12
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm	Chromatin Nucleus Transcription Regulator Complex
	Molecular Function	Fibroblast Growth Factor Receptor Binding Protein Binding Growth Factor Activity Heparin Binding Sodium Channel Regulator Activity	DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA Binding Protein Binding Sequence-specific Double-stranded DNA Binding
	Biological Process	Signal Transduction JNK Cascade Cell-cell Signaling Nervous System Development Fibroblast Growth Factor Receptor Signaling Pathway Neurogenesis	Skeletal System Development Regulation Of DNA-templated Transcription Regulation Of Transcription By RNA Polymerase II Pattern Specification Process Embryonic Digit Morphogenesis
Pathways		Phase 0 - rapid depolarisation
Drugs
Diseases		Spinocerebellar ataxia (SCA); Machado-Joseph disease (SCA3)
GWAS		Bone mineral density (hip) ( 30172743) Heel bone mineral density x serum urate levels interaction ( 34046847) Idiopathic downbeat nystagmus ( 32157568) LDL cholesterol change in response to fenofibrate in statin-treated type 2 diabetes ( 28736931) Maximum habitual alcohol consumption ( 31151762) Plasma parathyroid hormone levels ( 30134803) PR interval ( 32439900) Preeclampsia ( 23551011) Response to methylphenidate treatment in attention-deficit/hyperactivity disorder (blood pressure) ( 21130132) Response to protease inhibitor treatment in hepatitis c (bilirubin toxicity) ( 24503447) Total cholesterol change in response to fenofibrate in statin-treated type 2 diabetes ( 28736931)	Digit length ratio ( 29659830) Digit length ratio (left hand) ( 29659830) Digit length ratio (right hand) ( 29659830) Male-pattern baldness ( 28196072)
Interacting Genes		13 interacting genes: ACACA EHHADH FBXO34 FKBP8 FUNDC2 H4C7 HOXD12 MAOB RTP5 SCN8A SMC1A SYT16 TTPA	17 interacting genes: ACTN3 CABP2 CREBBP DTX2 FGF14 FRS3 MAF MAFB MAFF MAFG MAFK MEIS1 MKRN3 POLR1C TFAP2D TRAF1 TTC19
Entrez ID		2259	3238
HPRD ID		03305	00871
Ensembl ID		ENSG00000102466	ENSG00000170178
Uniprot IDs		A0A7U3JVZ8 A0A9L9PX77 A0A9L9PXK7 Q92915	P35452
PDB IDs
Enriched GO Terms of Interacting Partners?		Mitochondrial Envelope	RNA Polymerase II Transcription Regulator Complex DNA-binding Transcription Activator Activity, RNA Polymerase II-specific Chromatin DNA-binding Transcription Factor Activity DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Transcription Regulator Complex Positive Regulation Of Transcription By RNA Polymerase II Sequence-specific DNA Binding Embryo Development Ending In Birth Or Egg Hatching Multicellular Organism Development Chordate Embryonic Development In Utero Embryonic Development Negative Regulation Of Transcription By RNA Polymerase II Fibroblast Growth Factor Receptor Binding RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding Negative Regulation Of Nucleobase-containing Compound Metabolic Process DNA Binding Positive Regulation Of RNA Biosynthetic Process Positive Regulation Of DNA-templated Transcription Integrated Stress Response Signaling Regulation Of Nucleobase-containing Compound Metabolic Process Positive Regulation Of Glucose Catabolic Process To Lactate Via Pyruvate Identical Protein Binding Negative Regulation Of DNA-templated Transcription Positive Regulation Of RNA Metabolic Process Negative Regulation Of RNA Biosynthetic Process Rhombomere 6 Development Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of Transcription By RNA Polymerase II Regulation Of Multicellular Organismal Development Regulation Of The Force Of Skeletal Muscle Contraction Positive Regulation Of Fast-twitch Skeletal Muscle Fiber Contraction Negative Regulation Of RNA Metabolic Process Positive Regulation Of Nucleobase-containing Compound Metabolic Process Histone H3K27 Acetyltransferase Activity Fibroblast Growth Factor Receptor Signaling Pathway Regulation Of Epidermis Development Regulation Of Epidermal Cell Differentiation Abducens Nerve Formation Rhombomere 5 Development Inferior Colliculus Development Sequence-specific Double-stranded DNA Binding Regulation Of RNA Metabolic Process Positive Regulation Of Bone Mineralization Involved In Bone Maturation Regulation Of Cell Differentiation Histone H3K18 Acetyltransferase Activity N-terminal Peptidyl-lysine Acetylation Peptide Lactyltransferase (CoA-dependent) Activity Brain Segmentation
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?