FGF13 and VMP1

Number of citations of the paper that reports this interaction (PubMedID 33064958)
48

Data Source:
BioGRID (two hybrid)

		FGF13	VMP1
Description		fibroblast growth factor 13	vacuole membrane protein 1
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm Cytosol Microtubule Plasma Membrane Intercalated Disc Membrane Lateral Plasma Membrane Filopodium Axon Dendrite Growth Cone Sarcolemma Cell Projection Neuron Projection	Phagophore Assembly Site Autophagosome Membrane Nucleolus Vacuole Vacuolar Membrane Endoplasmic Reticulum Endoplasmic Reticulum Membrane Plasma Membrane Endomembrane System Membrane Endoplasmic Reticulum-Golgi Intermediate Compartment Membrane
	Molecular Function	Protein Binding Microtubule Binding Growth Factor Activity Sodium Channel Regulator Activity Transmembrane Transporter Binding Beta-tubulin Binding	Protein Binding Phospholipid Scramblase Activity
	Biological Process	MAPK Cascade Neuron Migration Sodium Ion Transport Negative Regulation Of Microtubule Depolymerization Signal Transduction Cell-cell Signaling Nervous System Development Learning Or Memory Learning Memory Hippocampus Development Cerebral Cortex Cell Migration Neurogenesis Establishment Of Neuroblast Polarity Microtubule Polymerization Negative Regulation Of Collateral Sprouting Branching Morphogenesis Of A Nerve Protein Localization To Plasma Membrane Regulation Of Cardiac Muscle Cell Action Potential Involved In Regulation Of Contraction Inhibitory Synapse Assembly Positive Regulation Of Voltage-gated Sodium Channel Activity	Autophagosome Assembly Lipid Transport Autophagy Golgi Organization Cell Adhesion Embryo Implantation Autophagosome Membrane Docking Plasma Membrane Phospholipid Scrambling Cell Junction Assembly Lipoprotein Transport Cell-cell Adhesion Organelle Localization By Membrane Tethering Positive Regulation Of ATPase-coupled Calcium Transmembrane Transporter Activity Mitochondrion-endoplasmic Reticulum Membrane Tethering
Pathways		Phase 0 - rapid depolarisation
Drugs
Diseases
GWAS		Breast cancer in BRCA2 mutation carriers ( 23544012) Response to taxane treatment (paclitaxel) ( 23006423)	Appendicular lean mass ( 33097823) Chronotype ( 30696823) Crohn's disease ( 28067908) Granulocyte count ( 27863252) Granulocyte percentage of myeloid white cells ( 27863252) Hematocrit ( 32888494 27863252) Hemoglobin ( 32888494 29403010) Hemoglobin concentration ( 27863252) Hemoglobin levels ( 32327693) Idiopathic dilated cardiomyopathy ( 29495422) Lymphocyte count ( 27863252) Monocyte count ( 27863252 32888494) Monocyte percentage of white cells ( 27863252 32888494) Multiple sclerosis ( 31604244 24076602) Myeloid white cell count ( 27863252) Neutrophil count ( 32888494 27863252) Platelet distribution width ( 32888494) Plateletcrit ( 32888494) Pulse pressure ( 27841878) Sum basophil neutrophil counts ( 27863252) Sum neutrophil eosinophil counts ( 27863252) Triglyceride levels ( 32203549 32154731) Urate levels ( 31578528) Waist circumference adjusted for body mass index ( 34021172) White blood cell count ( 27863252 32888494) White blood cell count (basophil) ( 27863252)
Interacting Genes		9 interacting genes: APP ARHGAP5 FBXO7 MAPK8IP2 PLEKHF2 PRNP PSEN1 SCN8A VMP1	9 interacting genes: CYB5R3 ERGIC3 FAM209A FGF13 HGS LMNA MEOX2 SLC39A9 TMEM41B
Entrez ID		2258	81671
HPRD ID		02090	15649
Ensembl ID		ENSG00000129682	ENSG00000062716
Uniprot IDs		A8K1P5 Q92913	B4DED7 B4DEJ9 B4DGZ7 K7EPE7 Q96GC9
PDB IDs		3HBW 4DCK 4JPZ
Enriched GO Terms of Interacting Partners?		Neuron Projection Maintenance Regulation Of Neuron Apoptotic Process Neuron Projection Organization Regulation Of Apoptotic Signaling Pathway Astrocyte Activation Involved In Immune Response Positive Regulation Of Amyloid Fibril Formation Cellular Response To Amyloid-beta Growth Factor Receptor Binding Response To Amyloid-beta Negative Regulation Of Apoptotic Signaling Pathway Positive Regulation Of Neuron Apoptotic Process Regulation Of Biological Quality Learning Or Memory Regulation Of Plasma Membrane Bounded Cell Projection Organization Regulation Of Cell Projection Organization Negative Regulation Of Long-term Synaptic Potentiation Cognition Regulation Of Dendritic Spine Maintenance Intracellular Copper Ion Homeostasis Regulation Of Amyloid Fibril Formation Regulation Of Membrane Potential Negative Regulation Of Signaling Negative Regulation Of Signal Transduction Regulation Of Apoptotic Process Mating Behavior Regulation Of Postsynapse Organization Astrocyte Activation Memory Regulation Of Programmed Cell Death Endoplasmic Reticulum Positive Regulation Of Glycolytic Process Negative Regulation Of Cell Communication Copper Ion Homeostasis Cellular Response To Copper Ion Negative Regulation Of Programmed Cell Death Negative Regulation Of Apoptotic Process Molecular Function Activator Activity Modulation Of Chemical Synaptic Transmission Reproductive Behavior Positive Regulation Of Apoptotic Process Response To Copper Ion Early Endosome Membrane Regulation Of Synaptic Plasticity Positive Regulation Of Programmed Cell Death Positive Regulation Of ATP Metabolic Process Membrane Raft Dendritic Shaft Postsynapse Regulation Of Long-term Synaptic Potentiation Regulation Of Intracellular Signal Transduction
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