VMP1 and TMEM41B

Number of citations of the paper that reports this interaction (PubMedID 30093494)
50

Data Source:
BioGRID (pull down)

		VMP1	TMEM41B
Description		vacuole membrane protein 1	transmembrane protein 41B
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Phagophore Assembly Site Autophagosome Membrane Nucleolus Vacuole Vacuolar Membrane Endoplasmic Reticulum Endoplasmic Reticulum Membrane Plasma Membrane Endomembrane System Membrane Endoplasmic Reticulum-Golgi Intermediate Compartment Membrane	Cytoplasm Endoplasmic Reticulum Endoplasmic Reticulum Membrane Endomembrane System Membrane Mitochondria-associated Endoplasmic Reticulum Membrane Contact Site
	Molecular Function	Protein Binding Phospholipid Scramblase Activity	Protein Binding Phospholipid Scramblase Activity
	Biological Process	Autophagosome Assembly Lipid Transport Autophagy Golgi Organization Cell Adhesion Embryo Implantation Autophagosome Membrane Docking Plasma Membrane Phospholipid Scrambling Cell Junction Assembly Lipoprotein Transport Cell-cell Adhesion Organelle Localization By Membrane Tethering Positive Regulation Of ATPase-coupled Calcium Transmembrane Transporter Activity Mitochondrion-endoplasmic Reticulum Membrane Tethering	Autophagosome Assembly Lipid Transport Autophagy Nervous System Development Plasma Membrane Phospholipid Scrambling Intracellular Lipid Transport Host-mediated Perturbation Of Viral RNA Genome Replication
Pathways
Drugs
Diseases
GWAS		Appendicular lean mass ( 33097823) Chronotype ( 30696823) Crohn's disease ( 28067908) Granulocyte count ( 27863252) Granulocyte percentage of myeloid white cells ( 27863252) Hematocrit ( 32888494 27863252) Hemoglobin ( 32888494 29403010) Hemoglobin concentration ( 27863252) Hemoglobin levels ( 32327693) Idiopathic dilated cardiomyopathy ( 29495422) Lymphocyte count ( 27863252) Monocyte count ( 27863252 32888494) Monocyte percentage of white cells ( 27863252 32888494) Multiple sclerosis ( 31604244 24076602) Myeloid white cell count ( 27863252) Neutrophil count ( 32888494 27863252) Platelet distribution width ( 32888494) Plateletcrit ( 32888494) Pulse pressure ( 27841878) Sum basophil neutrophil counts ( 27863252) Sum neutrophil eosinophil counts ( 27863252) Triglyceride levels ( 32203549 32154731) Urate levels ( 31578528) Waist circumference adjusted for body mass index ( 34021172) White blood cell count ( 27863252 32888494) White blood cell count (basophil) ( 27863252)	Pursuit maintenance gain ( 29064472)
Interacting Genes		9 interacting genes: CYB5R3 ERGIC3 FAM209A FGF13 HGS LMNA MEOX2 SLC39A9 TMEM41B	3 interacting genes: PDE4B SLC22A2 VMP1
Entrez ID		81671	440026
HPRD ID		15649	18632
Ensembl ID		ENSG00000062716	ENSG00000166471
Uniprot IDs		B4DED7 B4DEJ9 B4DGZ7 K7EPE7 Q96GC9	Q5BJD5
PDB IDs
Enriched GO Terms of Interacting Partners?			Neutrophil Homeostasis Negative Regulation Of Relaxation Of Muscle CAMP Catabolic Process Negative Regulation Of Adenylate Cyclase-activating Adrenergic Receptor Signaling Pathway Regulation Of Monoatomic Ion Transmembrane Transport Negative Regulation Of Relaxation Of Cardiac Muscle Regulation Of Relaxation Of Cardiac Muscle Serotonin Uptake Acetylcholine Transport Histamine Uptake Pyrimidine Nucleoside Transmembrane Transporter Activity Choline Transport Norepinephrine Uptake Prostaglandin Transmembrane Transporter Activity Xenobiotic Transport Across Blood-brain Barrier Spermidine Transport Lipid Transport Toxin Transmembrane Transporter Activity Monoamine Transmembrane Transporter Activity Epinephrine Transport Choline Transmembrane Transporter Activity Spermidine Transmembrane Transport Putrescine Transport Norepinephrine Transport Thiamine Transmembrane Transporter Activity Thiamine Transport Amine Transmembrane Transporter Activity Quaternary Ammonium Group Transmembrane Transporter Activity Spermidine Transmembrane Transporter Activity L-arginine Import Across Plasma Membrane Putrescine Transmembrane Transporter Activity Polyamine Transmembrane Transport Thiamine Transmembrane Transport Histamine Transport L-arginine Transmembrane Transporter Activity Acetylcholine Transmembrane Transporter Activity Regulation Of ATPase-coupled Calcium Transmembrane Transporter Activity Mitochondrion-endoplasmic Reticulum Membrane Tethering Autophagosome Membrane Docking Positive Regulation Of ATPase-coupled Calcium Transmembrane Transporter Activity Gamma-tubulin Complex Regulation Of Monoatomic Ion Transport Organic Cation Transmembrane Transporter Activity Efflux Transmembrane Transporter Activity L-arginine Transmembrane Transport Amine Transport Catecholamine Uptake Dopamine Uptake Cellular Response To Epinephrine Stimulus Azole Transmembrane Transport
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