FCGRT and ALB

Number of citations of the paper that reports this interaction (PMID 12566415)
62

Data Source:
HPRD (in vivo)

		FCGRT	ALB
Gene Name		Fc fragment of IgG, receptor, transporter, alpha	albumin
Image
Gene Ontology Annotations	Cellular Component	Plasma Membrane Integral Component Of Membrane	Extracellular Region Basement Membrane Extracellular Space Nucleus Platelet Alpha Granule Lumen Protein Complex Extracellular Vesicular Exosome Blood Microparticle
	Molecular Function	Antigen Binding IgG Receptor Activity IgG Binding Beta-2-microglobulin Binding	DNA Binding Fatty Acid Binding Copper Ion Binding Protein Binding Drug Binding Zinc Ion Binding Toxic Substance Binding Antioxidant Activity Oxygen Binding Enzyme Binding Pyridoxal Phosphate Binding Chaperone Binding
	Biological Process	IgG Immunoglobulin Transcytosis In Epithelial Cells Mediated By FcRn Immunoglobulin Receptor Immune Response Antigen Processing And Presentation Fc-gamma Receptor Signaling Pathway	Retina Homeostasis Platelet Degranulation Transport Receptor-mediated Endocytosis Response To Nutrient Blood Coagulation Bile Acid Metabolic Process Cellular Response To Starvation Response To Organic Substance Bile Acid And Bile Salt Transport Hemolysis By Symbiont Of Host Erythrocytes Platelet Activation Lipoprotein Metabolic Process Negative Regulation Of Apoptotic Process Negative Regulation Of Programmed Cell Death Sodium-independent Organic Anion Transport Small Molecule Metabolic Process Positive Regulation Of Circadian Sleep/wake Cycle, Non-REM Sleep Response To Mercury Ion Maintenance Of Mitochondrion Location Transmembrane Transport Response To Platinum Ion
Pathways			Lipoprotein metabolism Bile acid and bile salt metabolism Metabolism of lipids and lipoproteins Recycling of bile acids and salts Platelet degranulation Lipid digestion, mobilization, and transport Transport of organic anions SLC-mediated transmembrane transport HDL-mediated lipid transport Scavenging of heme from plasma Response to elevated platelet cytosolic Ca2+ Platelet activation, signaling and aggregation Transport of vitamins, nucleosides, and related molecules
Drugs
Diseases
GWAS		Hematological and biochemical traits ( 20139978) Serum albumin level ( 23022100) Serum total protein level ( 23022100)	Lipid metabolism phenotypes ( 22286219) Prostate cancer ( 23535732)
Protein-Protein Interactions		3 interactors: ALB B2M CA6	24 interactors: AGA AMBP APOE APP CRYAA CUBN F7 FCGRT HNF1A IMMT KLK3 LRP2 LUC7L2 NR5A2 ORM1 PFDN1 PON1 PRB3 RBP4 RYR2 SRGN ST13 TK1 YWHAG
Entrez ID		2217	213
HPRD ID		03257	00062
Ensembl ID		ENSG00000104870	ENSG00000163631
Uniprot IDs		M0R0A9 P55899	C9JKR2 P02768
PDB IDs		1EXU 3M17 3M1B	1AO6 1BJ5 1BKE 1BM0 1E78 1E7A 1E7B 1E7C 1E7E 1E7F 1E7G 1E7H 1E7I 1GNI 1GNJ 1H9Z 1HA2 1HK1 1HK2 1HK3 1HK4 1HK5 1N5U 1O9X 1TF0 1UOR 1YSX 2BX8 2BXA 2BXB 2BXC 2BXD 2BXE 2BXF 2BXG 2BXH 2BXI 2BXK 2BXL 2BXM 2BXN 2BXO 2BXP 2BXQ 2ESG 2I2Z 2I30 2VDB 2VUE 2VUF 2XSI 2XVQ 2XVU 2XVV 2XVW 2XW0 2XW1 2YDF 3A73 3B9L 3B9M 3CX9 3JQZ 3JRY 3LU6 3LU7 3LU8 3SQJ 3TDL 3UIV 4E99 4EMX 4G03 4G04 4HGK 4HGM 4IW1 4IW2 4K2C 4L8U 4L9K 4L9Q 4LA0 4LB2 4LB9
Enriched GO Terms of Interacting Partners?		Retina Homeostasis Tissue Homeostasis Maintenance Of Mitochondrion Location Multicellular Organismal Homeostasis Response To Platinum Ion Hemolysis By Symbiont Of Host Erythrocytes Positive Regulation Of Circadian Sleep/wake Cycle, Non-REM Sleep Antigen Processing And Presentation Of Exogenous Protein Antigen Via MHC Class Ib, TAP-dependent Response To Metal Ion Regulation Of Circadian Sleep/wake Cycle, Non-REM Sleep Organic Anion Transport Response To Inorganic Substance Sodium-independent Organic Anion Transport Regulation Of Circadian Sleep/wake Cycle, Sleep Establishment Of Epithelial Cell Polarity Anion Transport Positive Regulation Of Circadian Rhythm Protein Refolding Cell Activation Killing Of Cells Of Other Organism Cytolysis Regulation Of Defense Response To Virus By Virus Detection Of Chemical Stimulus Involved In Sensory Perception Of Bitter Taste Response To Mercury Ion Bicarbonate Transport Bile Acid And Bile Salt Transport Sensory Perception Of Bitter Taste Mitochondrion Localization Detection Of Chemical Stimulus Involved In Sensory Perception Of Taste Bile Acid Metabolic Process One-carbon Metabolic Process Response To Cadmium Ion Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class I, TAP-independent Sensory Perception Of Taste T Cell Differentiation In Thymus Platelet Degranulation Apical Junction Assembly Homeostatic Process Regulation Of Defense Response To Virus Positive Regulation Of T Cell Mediated Cytotoxicity Regulation Of T Cell Mediated Cytotoxicity Regulation Of Circadian Rhythm Positive Regulation Of Leukocyte Mediated Cytotoxicity Interaction With Host Positive Regulation Of T Cell Mediated Immunity Positive Regulation Of Cell Killing Regulation Of Leukocyte Mediated Cytotoxicity Establishment Of Cell Polarity Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class I, TAP-dependent Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class I	Alcohol Metabolic Process Steroid Metabolic Process Cholesterol Metabolic Process Sterol Metabolic Process Chemical Homeostasis Lipid Metabolic Process Homeostatic Process Response To External Stimulus Response To Stimulus Phototransduction, Visible Light Retinoid Metabolic Process Tetrapyrrole Metabolic Process Vitamin D Metabolic Process Diterpenoid Metabolic Process Detection Of Visible Light Phototransduction Regulation Of Blood Coagulation Response To Lipid Positive Regulation Of Cholesterol Efflux Reverse Cholesterol Transport Detection Of Light Stimulus Positive Regulation Of Cholesterol Transport Cellular Calcium Ion Homeostasis Calcium Ion Homeostasis System Development Isoprenoid Metabolic Process Small Molecule Metabolic Process Regulation Of Cholesterol Efflux Response To Hormone Regulation Of Wound Healing Organ Development Response To Light Stimulus Vesicle-mediated Transport Receptor-mediated Endocytosis Endocytosis Regulation Of Cellular Localization Response To Organic Substance Response To Wounding Response To Abiotic Stimulus Cellular Metal Ion Homeostasis Positive Regulation Of Transport Bile Acid Metabolic Process Detection Of Abiotic Stimulus Regulation Of Cholesterol Transport Blood Coagulation Tissue Homeostasis Hemostasis Response To Nutrient Levels Heme Metabolic Process Multicellular Organismal Development
Tagcloud ?			ambulatory anabolic anthropometric calls capd catabolism causal complicating declined deterioration dialysis haemodialysis instead malnutrition mmol nutrineal nutrition osmotic peritoneal phosphates phosphorus rule solution substituted termination transferrin uraemic urea wilcoxon
Tagcloud (Difference) ?			ambulatory anabolic anthropometric calls capd catabolism causal complicating declined deterioration dialysis haemodialysis instead malnutrition mmol nutrineal nutrition osmotic peritoneal phosphates phosphorus rule solution substituted termination transferrin uraemic urea wilcoxon
Tagcloud (Intersection) ?