DRC5 and TAF8

		DRC5	TAF8
Description		dynein regulatory complex subunit 5	TATA-box binding protein associated factor 8
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GO Annotations	Cellular Component	Cytoplasm Cytoskeleton Cilium Motile Cilium Sperm Flagellum Cell Projection	Nucleus Nucleoplasm Transcription Factor TFIID Complex Cytoplasm Perinuclear Region Of Cytoplasm
	Molecular Function	Protein Binding	Protein Binding RNA Polymerase II General Transcription Initiation Factor Activity Protein Heterodimerization Activity
	Biological Process	Microtubule-based Movement Flagellated Sperm Motility	DNA-templated Transcription Open Complex Formation Inner Cell Mass Cell Proliferation Transcription Initiation At RNA Polymerase II Promoter Cell Differentiation MRNA Transcription By RNA Polymerase II Regulation Of Fat Cell Differentiation RNA Polymerase II Preinitiation Complex Assembly Maintenance Of Protein Location In Nucleus Positive Regulation Of Transcription Initiation By RNA Polymerase II
Pathways			RNA polymerase II transcribes snRNA genes RNA polymerase II transcribes snRNA genes
Drugs
Diseases
GWAS			Exploratory eye movement dysfunction in schizophrenia (cognitive search score) ( 26242244) Exploratory eye movement dysfunction in schizophrenia (number of eye fixations) ( 26242244) Exploratory eye movement dysfunction in schizophrenia (responsive search score) ( 26242244) HDL cholesterol levels ( 28334899) Hemoglobin levels ( 33491795) Lymphocyte count ( 32888494) Lymphocyte percentage of white cells ( 32888494) Mosaic loss of chromosome Y (Y chromosome dosage) ( 31624269) Neutrophil percentage of white cells ( 32888494)
Interacting Genes			13 interacting genes: H3-4 KPNA2 KPNB1 TAF1 TAF10 TAF11 TAF12 TAF2 TAF4 TAF5 TAF6 TAF7 TAF9
Entrez ID		202500	129685
HPRD ID		14568	18167
Ensembl ID		ENSG00000146221	ENSG00000137413
Uniprot IDs		Q5JU00	A0A8I5KXI2 A0A8I5QL44 Q7Z7C8
PDB IDs		8J07	4WV4 4WV6 5FUR 6MZC 6MZL 6MZM 7EDX 7EG7 7EG8 7EG9 7EGA 7EGB 7EGC 7EGD 7EGE 7EGG 7EGH 7EGI 7EGJ 7ENA 7ENC 8GXQ 8GXS 8WAK 8WAL 8WAN 8WAO 8WAP 8WAQ 8WAR 8WAS
Enriched GO Terms of Interacting Partners?		DNA-templated Transcription Open Complex Formation Radial Spoke Head 1 Radial Spoke Assembly Radial Spoke Head 3 Axonemal Central Apparatus Assembly Radial Spoke Head	Transcription Factor TFIID Complex RNA Polymerase II General Transcription Initiation Factor Activity MRNA Transcription By RNA Polymerase II RNA Polymerase II Preinitiation Complex Assembly MRNA Transcription Transcription Preinitiation Complex Assembly Positive Regulation Of Transcription Initiation By RNA Polymerase II Transcription Factor TFTC Complex Positive Regulation Of DNA-templated Transcription Initiation Regulation Of Transcription Initiation By RNA Polymerase II DNA-templated Transcription Initiation Regulation Of DNA-templated Transcription Initiation Transcription Initiation At RNA Polymerase II Promoter Protein-DNA Complex Assembly Transcription By RNA Polymerase II DNA-templated Transcription Regulation Of DNA Repair MRNA Metabolic Process Protein-containing Complex Assembly Protein-containing Complex Organization MLL1 Complex Regulation Of DNA Metabolic Process Protein Heterodimerization Activity Positive Regulation Of RNA Biosynthetic Process Positive Regulation Of DNA-templated Transcription Nucleobase-containing Compound Biosynthetic Process Positive Regulation Of RNA Metabolic Process Cellular Component Assembly Positive Regulation Of Nucleobase-containing Compound Metabolic Process SAGA Complex Regulation Of Cellular Response To Stress Positive Regulation Of Transcription By RNA Polymerase II RNA Metabolic Process Positive Regulation Of Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Nucleic Acid Metabolic Process Positive Regulation Of Biosynthetic Process Nucleoplasm Positive Regulation Of Macromolecule Metabolic Process Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process Nucleobase-containing Compound Metabolic Process Regulation Of RNA Metabolic Process Positive Regulation Of Metabolic Process TBP-class Protein Binding Histone Acetyltransferase Activity Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of Transcription By RNA Polymerase II Male Germ Cell Nucleus Aryl Hydrocarbon Receptor Binding
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