SPATS1 and GPHN

Number of citations of the paper that reports this interaction (PubMedID 21988832)
38

Data Source:
BioGRID (two hybrid)

		SPATS1	GPHN
Description		spermatogenesis associated serine rich 1	gephyrin
Image		No pdb structure
GO Annotations	Cellular Component		Cytoplasm Cytosol Cytoskeleton Plasma Membrane Cytoplasmic Side Of Plasma Membrane Postsynaptic Density Membrane Dendrite Cell Projection Dendritic Spine Synapse Postsynaptic Membrane Inhibitory Synapse Synaptic Membrane Glycinergic Synapse Postsynapse GABA-ergic Synapse Postsynaptic Specialization, Intracellular Component Postsynaptic Specialization
	Molecular Function	Protein Binding	Nucleotide Binding Catalytic Activity Signaling Receptor Binding Protein Binding ATP Binding Nitrate Reductase Activity Transferase Activity Protein-macromolecule Adaptor Activity Identical Protein Binding Molybdopterin Cofactor Binding Metal Ion Binding Molecular Adaptor Activity Molybdopterin Adenylyltransferase Activity Molybdopterin Molybdotransferase Activity
	Biological Process		Mo-molybdopterin Cofactor Biosynthetic Process Synapse Assembly Establishment Of Synaptic Specificity At Neuromuscular Junction Response To Metal Ion Molybdopterin Cofactor Biosynthetic Process Establishment Of Protein Localization Synapse Organization Synaptic Transmission, GABAergic Glycine Receptor Clustering Protein Localization To Membrane Gamma-aminobutyric Acid Receptor Clustering Neurotransmitter Receptor Localization To Postsynaptic Specialization Membrane
Pathways			Molybdenum cofactor biosynthesis
Drugs			Formic acid Imidazole Propanoic acid
Diseases			Hyperekplexia
GWAS		Itch intensity from mosquito bite adjusted by bite size ( 28199695)	Appendicular lean mass ( 33097823) Depression (quantitative trait) ( 23290196) Pneumococcal meningitis ( 31092817) Tandem gait ( 26219847) Waist circumference adjusted for body mass index ( 28552196)
Interacting Genes		9 interacting genes: CFLAR CTNNA3 GPHN KCTD9 MISP SPG7 TRIM55 TRIM63 ZIC1	15 interacting genes: ACADVL ARHGEF9 DYNLL1 DYNLL2 ENAH GABARAP GLRB KHDRBS1 MITD1 MTOR PFN1 PIN1 PSMA1 SPATS1 TUBA4A
Entrez ID		221409	10243
HPRD ID		10248	04893
Ensembl ID		ENSG00000249481	ENSG00000171723
Uniprot IDs		Q496A3	Q9NQX3
PDB IDs			1JLJ
Enriched GO Terms of Interacting Partners?		Skeletal Muscle Atrophy Skeletal Muscle Adaptation Striated Muscle Atrophy Muscle Atrophy Glycine Receptor Clustering Molybdopterin Adenylyltransferase Activity Molybdopterin Molybdotransferase Activity M-AAA Complex Microtubule-based Process Skeletal Myofibril Assembly Nitrate Reductase Activity Establishment Of Synaptic Specificity At Neuromuscular Junction Cytoskeleton Response To Electrical Stimulus Involved In Regulation Of Muscle Adaptation	GABA-ergic Synapse Microtubule Associated Complex Protein-containing Complex Binding Postsynaptic Specialization Cytoskeleton Organization Microtubule Cytoplasmic Dynein Complex Regulation Of Protein Stability Positive Regulation Of Epithelial Cell Migration Positive Regulation Of Translational Initiation Positive Regulation Of Actin Filament Polymerization Phosphoprotein Binding Positive Regulation Of SCF-dependent Proteasomal Ubiquitin-dependent Catabolic Process Glycine-gated Chloride Channel Complex Extracellularly Glycine-gated Ion Channel Activity Cis-trans Isomerase Activity Microtubule-based Process Ciliary Tip Dynein Intermediate Chain Binding Dynein Complex Grb2-Sos Complex Myosin V Complex Protein Domain Specific Binding Cytoskeleton Cytosol Protein Stabilization Positive Regulation Of Actin Filament Bundle Assembly Microtubule Cytoskeleton
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