ABCD3

Description		ATP binding cassette subfamily D member 3
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GO Annotations	Cellular Component	Mitochondrion Peroxisome Peroxisomal Membrane Peroxisomal Matrix Cytosol Membrane
	Molecular Function	Nucleotide Binding Long-chain Fatty Acid Transmembrane Transporter Activity Protein Binding ATP Binding Hydrolase Activity ATP Hydrolysis Activity ATPase-coupled Transmembrane Transporter Activity Identical Protein Binding Protein Homodimerization Activity Fatty Acyl-CoA Hydrolase Activity ABC-type Transporter Activity
	Biological Process	Very Long-chain Fatty Acid Metabolic Process Fatty Acid Biosynthetic Process Fatty Acid Beta-oxidation Bile Acid Biosynthetic Process Lipid Transport Peroxisome Organization Response To Xenobiotic Stimulus Bile Acid And Bile Salt Transport Long-chain Fatty Acid Import Into Peroxisome Very Long-chain Fatty Acid Catabolic Process Transmembrane Transport Phytanic Acid Metabolic Process
Pathways		ABC transporters in lipid homeostasis RHOA GTPase cycle RHOC GTPase cycle Class I peroxisomal membrane protein import
Drugs
Diseases
GWAS
Novel Interacting Genes		1 novel interacting genes: ACADM
Interacting Genes		7 interacting genes: ABCD1 ABCD2 COL6A2 PEX19 PSMA1 TUFT1 UBC
Entrez ID		5825
HPRD ID		01368
Ensembl ID		ENSG00000117528
Uniprot IDs		P28288
PDB IDs		8Z0F 8Z9X
Enriched GO Terms of Interacting Partners?		Peroxisomal Membrane Transport Organophosphate Ester Transmembrane Transporter Activity Nucleobase-containing Compound Transmembrane Transporter Activity Peroxisome Organization Sulfur Compound Transmembrane Transporter Activity Amide Transmembrane Transporter Activity Long-chain Fatty Acid Import Into Peroxisome Fatty Acid Beta-oxidation Peroxisomal Membrane Very Long-chain Fatty Acid Catabolic Process Fatty Acid Oxidation Fatty Acid Catabolic Process Lipid Oxidation Positive Regulation Of Fatty Acid Beta-oxidation Positive Regulation Of Unsaturated Fatty Acid Biosynthetic Process Neuron Projection Maintenance Positive Regulation Of Fatty Acid Oxidation Fatty Acyl-CoA Hydrolase Activity Myelin Maintenance Alpha-linolenic Acid Metabolic Process Peroxisome Long-chain Fatty Acid Transmembrane Transporter Activity Regulation Of Fatty Acid Beta-oxidation Negative Regulation Of Reactive Oxygen Species Biosynthetic Process Lipid Modification Linoleic Acid Metabolic Process Positive Regulation Of Fatty Acid Biosynthetic Process Positive Regulation Of Lipid Catabolic Process ATPase-coupled Transmembrane Transporter Activity Regulation Of Fatty Acid Oxidation Carboxylic Acid Catabolic Process Very Long-chain Fatty Acid Metabolic Process Intracellular Lipid Transport Long-chain Fatty Acid Biosynthetic Process Negative Regulation Of Reactive Oxygen Species Metabolic Process Positive Regulation Of Fatty Acid Metabolic Process ABC-type Transporter Activity Regulation Of Reactive Oxygen Species Biosynthetic Process Unsaturated Fatty Acid Biosynthetic Process Neuron Projection Organization Lipid Catabolic Process Negative Regulation Of Cytokine Production Involved In Inflammatory Response Regulation Of Fatty Acid Biosynthetic Process Long-chain Fatty Acid Transport Fatty Acid Derivative Biosynthetic Process Fatty Acid Metabolic Process Regulation Of Lipid Catabolic Process Regulation Of Small Molecule Metabolic Process Very Long-chain Fatty-acyl-CoA Catabolic Process ABC-type Fatty-acyl-CoA Transporter Activity
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