ARID4B and DNAAF6

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		ARID4B	DNAAF6
Description		AT-rich interaction domain 4B	dynein axonemal assembly factor 6
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Mitochondrion Cytosol Sin3-type Complex	Cytoplasm Golgi Apparatus Trans-Golgi Network
	Molecular Function	Transcription Cis-regulatory Region Binding DNA Binding Protein Binding	Protein Binding Dynein Intermediate Chain Binding Protein-folding Chaperone Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Chromatin Organization Regulation Of Transcription By RNA Polymerase II Transcription By RNA Polymerase II Spermatogenesis Negative Regulation Of Cell Migration Negative Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Positive Regulation Of Transcription By RNA Polymerase II Genomic Imprinting Establishment Of Sertoli Cell Barrier Negative Regulation Of Stem Cell Population Maintenance Positive Regulation Of Stem Cell Population Maintenance	Cilium Movement Flagellated Sperm Motility Outer Dynein Arm Assembly Inner Dynein Arm Assembly Axonemal Dynein Complex Assembly
Pathways		HDACs deacetylate histones NoRC negatively regulates rRNA expression Potential therapeutics for SARS
Drugs
Diseases
GWAS		Appendicular lean mass ( 33097823) Asthma ( 29273806) Monocyte count ( 32888494) Monocyte percentage of white cells ( 32888494) Night sleep phenotypes ( 27126917) Plateletcrit ( 32888494)
Interacting Genes		15 interacting genes: DNAAF6 DYNLT1 EAF1 ETS1 HNRNPA2B1 NHSL2 NTAQ1 PIK3R3 PLEKHF2 PRR23B PTGES3L-AARSD1 RANBP2 SAP130 SIN3A SPANXB1	16 interacting genes: ARID4B BTAF1 CCAR1 CDKL3 GAS2L2 KAT5 KIF13A MCM7 P2RX4 PID1 POLDIP2 PRKAA2 QRICH1 RNF39 TSEN15 YAF2
Entrez ID		51742	139212
HPRD ID		10661	06650
Ensembl ID		ENSG00000054267	ENSG00000080572
Uniprot IDs		Q4LE39	Q9NQM4
PDB IDs		7DM4
Enriched GO Terms of Interacting Partners?		Dynein Intermediate Chain Binding Transport Of Viral Material Towards Nucleus Microtubule-dependent Intracellular Transport Of Viral Material Towards Nucleus Cellular Response To Tert-butyl Hydroperoxide Positive Regulation Of Stem Cell Population Maintenance Sin3-type Complex Negative Regulation Of Stem Cell Population Maintenance Response To Methylglyoxal Protein-N-terminal Glutamine Amidohydrolase Activity	Lipid Droplet Disassembly Phosphatidylethanolamine Biosynthetic Process Positive Regulation Of Biosynthetic Process Phosphatidylethanolamine Metabolic Process Phosphatidylcholine Biosynthetic Process CGAS/STING Signaling Pathway
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