EPB41L2 and FKBP2

Number of citations of the paper that reports this interaction (PMID 9531554)
13

Data Source:
BioGRID (affinity chromatography technology)
HPRD (in vitro, two hybrid, in vivo)

		EPB41L2	FKBP2
Gene Name		erythrocyte membrane protein band 4.1-like 2	FK506 binding protein 2, 13kDa
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Nucleoplasm Plasma Membrane Focal Adhesion Spectrin COP9 Signalosome Extrinsic Component Of Membrane Cell Junction Extracellular Vesicular Exosome	Endoplasmic Reticulum Endoplasmic Reticulum Membrane Extracellular Vesicular Exosome
	Molecular Function	Actin Binding Structural Molecule Activity PH Domain Binding	Peptidyl-prolyl Cis-trans Isomerase Activity Protein Binding FK506 Binding
	Biological Process	Cortical Actin Cytoskeleton Organization	Protein Peptidyl-prolyl Isomerization Chaperone-mediated Protein Folding
Pathways
Drugs
Diseases
GWAS		Lentiform nucleus volume ( 22903471) Response to statin therapy (LDL-C) ( 22331829)
Protein-Protein Interactions		13 interactors: ACTA1 ADORA1 APP ATXN1L DRD1 DRD3 FKBP2 GRIA1 NUMA1 SPTAN1 YWHAG YWHAH YWHAZ	13 interactors: ARFGEF1 BAG6 BARD1 C1QC EPB41 EPB41L2 MAPK3 RAB3C RAB6A RAP2A UBQLN1 UBQLN4 VAMP2
Entrez ID		2037	2286
HPRD ID		09126	01742
Ensembl ID		ENSG00000079819	ENSG00000173486
Uniprot IDs		B4DJ76 E9PHY5 E9PII3 I6L9B1 O43491 O60642 Q59FD8	P26885 Q53XJ5
PDB IDs			2PBC
Enriched GO Terms of Interacting Partners?		Regulation Of Synaptic Transmission Regulation Of Synaptic Plasticity Positive Regulation Of Protein Insertion Into Mitochondrial Membrane Involved In Apoptotic Signaling Pathway Cognition Positive Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway Positive Regulation Of Transport Positive Regulation Of Mitochondrion Organization System Development Visual Learning Negative Regulation Of Synaptic Transmission Visual Behavior Neuron-neuron Synaptic Transmission Apoptotic Process Positive Regulation Of Intracellular Transport Programmed Cell Death Regulation Of Cellular Localization Cell Death Death Learning Or Memory Regulation Of Dopamine Uptake Involved In Synaptic Transmission Associative Learning Multicellular Organismal Development Regulation Of Mitochondrion Organization Anatomical Structure Development Synaptic Transmission, Dopaminergic Behavioral Response To Cocaine Apoptotic Signaling Pathway Regulation Of Neurotransmitter Uptake Adenylate Cyclase-activating Dopamine Receptor Signaling Pathway Establishment Of Localization In Cell Prepulse Inhibition Adenylate Cyclase-modulating G-protein Coupled Receptor Signaling Pathway Regulation Of Circadian Sleep/wake Cycle, Sleep Long Term Synaptic Depression Regulation Of Synaptic Transmission, Dopaminergic Neuromuscular Process Positive Regulation Of Organelle Organization Learning Regulation Of Signaling Regulation Of Anion Transport Protein Targeting Developmental Process Regulation Of Renal Sodium Excretion G-protein Coupled Receptor Signaling Pathway, Coupled To Cyclic Nucleotide Second Messenger Regulation Of Intracellular Transport Nervous System Development Intracellular Transport Cell-cell Signaling Regulation Of Excretion	Ras Protein Signal Transduction Cortical Actin Cytoskeleton Organization Regulation Of Protein Metabolic Process Establishment Of Protein Localization Endomembrane System Organization Cortical Cytoskeleton Organization Small GTPase Mediated Signal Transduction Protein Localization Regulation Of Cellular Protein Metabolic Process Synaptic Vesicle Exocytosis Rab Protein Signal Transduction Cellular Protein Localization Immune System Process Negative Regulation Of Apolipoprotein Binding Positive Regulation Of Protein Glycosylation In Golgi Vesicle-mediated Transport Exocytosis Protein Localization To Membrane Cellular Localization Regulation Of Vesicle-mediated Transport Regulation Of Protein Catabolic Process Negative Regulation Of MRNA 3'-end Processing Regulation Of Intracellular Transport Neurotransmitter Secretion Synaptic Vesicle Transport Minus-end-directed Organelle Transport Along Microtubule Peptidyl-cysteine Methylation Eosinophil Degranulation Regulation Of Cellular Localization Intracellular Signal Transduction Regulation Of Golgi Inheritance Positive Regulation Of Protein Glycosylation Secretion By Cell Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Regulation Of Neurotransmitter Levels Caveolin-mediated Endocytosis Positive Regulation Of Histone Phosphorylation Regulation Of Protein Binding Protein Localization To Plasma Membrane Regulation Of Exocytosis Response To Endoplasmic Reticulum Stress Positive Regulation Of Protein Metabolic Process Tail-anchored Membrane Protein Insertion Into ER Membrane Negative Regulation Of Protein Export From Nucleus Neurotransmitter Transport Actin Cytoskeleton Organization Organelle Organization Regulation Of Golgi Organization Protein K6-linked Ubiquitination Negative Regulation Of Granulocyte Differentiation
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