ADCK5 and HSPA6

Number of citations of the paper that reports this interaction (PMID 21988832)
14

Data Source:
BioGRID (two hybrid)

		ADCK5	HSPA6
Gene Name		aarF domain containing kinase 5	heat shock 70kDa protein 6 (HSP70B)
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Mitochondrion Integral Component Of Membrane	Cytoplasm Centriole Cytosol COP9 Signalosome Extracellular Vesicular Exosome Blood Microparticle
	Molecular Function	Protein Serine/threonine Kinase Activity	ATP Binding Enzyme Binding Heat Shock Protein Binding ATPase Activity, Coupled Unfolded Protein Binding
	Biological Process	Protein Phosphorylation	Response To Unfolded Protein Cellular Response To Heat Protein Refolding Cellular Heat Acclimation
Pathways
Drugs
Diseases
GWAS			Helicobacter pylori serologic status ( 23652523) Inflammatory bowel disease ( 23128233) Ulcerative colitis ( 21297633)
Protein-Protein Interactions		3 interactors: HSPA6 NOTCH2NL RHOD	5 interactors: ADCK5 CISH CYP4F12 DNAJB4 TERF1
Entrez ID		203054	3310
HPRD ID		12427	00775
Ensembl ID		ENSG00000173137	ENSG00000173110
Uniprot IDs		Q3MIX3	P17066
PDB IDs			3FE1
Enriched GO Terms of Interacting Partners?			Negative Regulation Of Telomere Maintenance Via Semi-conservative Replication Telomeric Loop Formation Pressure Natriuresis Age-dependent Telomere Shortening Vitamin K Biosynthetic Process Telomere Maintenance Via Telomere Shortening Leukotriene B4 Catabolic Process Vitamin E Metabolic Process Negative Regulation Of Telomere Maintenance Via Telomerase Vitamin K Metabolic Process Negative Regulation Of Transferase Activity Long-chain Fatty Acid Catabolic Process Replicative Cell Aging Regulation Of Nuclear Cell Cycle DNA Replication Negative Regulation Of Telomerase Activity Telomere Maintenance Via Telomerase Negative Regulation Of Telomere Maintenance Regulation Of Telomere Maintenance Via Telomerase Positive Regulation Of Microtubule Polymerization Regulation Of Telomerase Activity Epoxygenase P450 Pathway Regulation Of Telomere Maintenance RNA-dependent DNA Replication JAK-STAT Cascade Involved In Growth Hormone Signaling Pathway Negative Regulation Of JAK-STAT Cascade Negative Regulation Of DNA Biosynthetic Process Sodium Ion Homeostasis Growth Hormone Receptor Signaling Pathway Cellular Response To Growth Hormone Stimulus Renal Water Homeostasis Regulation Of Microtubule Polymerization Telomere Maintenance Via Telomere Lengthening Very Long-chain Fatty Acid Metabolic Process Leukotriene Metabolic Process Mitotic Spindle Assembly Checkpoint Spindle Assembly Checkpoint Quinone Metabolic Process Drug Metabolic Process Negative Regulation Of Insulin Receptor Signaling Pathway Mitotic Spindle Checkpoint Response To Growth Hormone Positive Regulation Of Mitotic Nuclear Division Negative Regulation Of Chromosome Segregation Regulation Of DNA Biosynthetic Process Spindle Checkpoint Regulation Of Mitotic Sister Chromatid Separation Negative Regulation Of Mitotic Nuclear Division Negative Regulation Of DNA Replication Negative Regulation Of Catalytic Activity Multicellular Organismal Water Homeostasis
Tagcloud ?			chaperone complement defective dnaja1 dnajb1 enlarged experimentally heat hspa1a hsps initiated interpreted keratinocytes knockin nfkappab nodes participation peroxisome physiologic ppar proliferator represses repression shock spleen stressed tnfalpha tnip1
Tagcloud (Difference) ?			chaperone complement defective dnaja1 dnajb1 enlarged experimentally heat hspa1a hsps initiated interpreted keratinocytes knockin nfkappab nodes participation peroxisome physiologic ppar proliferator represses repression shock spleen stressed tnfalpha tnip1
Tagcloud (Intersection) ?