UNC13D and RAB27B

Number of citations of the paper that reports this interaction (PMID 14699162)
31

Data Source:
HPRD (in vitro)

		UNC13D	RAB27B
Gene Name		unc-13 homolog D (C. elegans)	RAB27B, member RAS oncogene family
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Lysosome Late Endosome Membrane Weibel-Palade Body Recycling Endosome Exocytic Vesicle	Golgi Stack Apical Plasma Membrane Trans-Golgi Network Transport Vesicle Secretory Granule Multivesicular Body Membrane Melanosome Zymogen Granule Membrane Extracellular Vesicular Exosome
	Molecular Function	Protein Binding Rab GTPase Binding	GTPase Activity Protein Binding GTP Binding GDP Binding Protein Domain Specific Binding Myosin V Binding
	Biological Process	Granuloma Formation Germinal Center Formation Phagocytosis Regulation Of Mast Cell Degranulation Natural Killer Cell Degranulation Positive Regulation Of Exocytosis Defense Response To Virus Positive Regulation Of Regulated Secretory Pathway	Intracellular Protein Transport Vesicle Docking Involved In Exocytosis Protein Secretion Melanosome Transport Rab Protein Signal Transduction Positive Regulation Of Exocytosis Multivesicular Body Sorting Pathway
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions		3 interactors: LMNA RAB27A RAB27B	8 interactors: DHPS MLPH RPH3AL SYTL1 SYTL2 SYTL4 SYTL5 UNC13D
Entrez ID		201294	5874
HPRD ID		10598	04846
Ensembl ID		ENSG00000092929	ENSG00000041353
Uniprot IDs		Q70J99	O00194
PDB IDs			2F7S
Enriched GO Terms of Interacting Partners?		Multivesicular Body Sorting Pathway Melanosome Transport Pigment Granule Transport Establishment Of Melanosome Localization Melanosome Localization Cellular Pigmentation Rab Protein Signal Transduction Positive Regulation Of Exocytosis Vesicle Docking Involved In Exocytosis Vesicle Docking Membrane Docking Intracellular Protein Transport Pigmentation Protein Secretion Regulation Of Cellular Localization Positive Regulation Of Constitutive Secretory Pathway Complement-dependent Cytotoxicity Sterol Regulatory Element Binding Protein Import Into Nucleus Regulation Of Exocytosis Cellular Protein Localization Establishment Of Vesicle Localization Protein Transport Vesicle Localization Multivesicular Body Organization Cytotoxic T Cell Degranulation Establishment Of Protein Localization Ras Protein Signal Transduction Intracellular Transport Establishment Or Maintenance Of Microtubule Cytoskeleton Polarity Exosomal Secretion Protein Localization Establishment Of Organelle Localization Positive Regulation Of Secretion Exocytosis Establishment Of Localization In Cell Natural Killer Cell Degranulation Regulation Of Vesicle-mediated Transport Organelle Localization Protein Targeting Endomembrane System Organization Positive Regulation Of Cell Aging T Cell Mediated Cytotoxicity Cellular Localization Mitotic Nuclear Envelope Reassembly Secretion By Cell Nuclear Envelope Reassembly SREBP Signaling Pathway Response To Sterol Depletion Small GTPase Mediated Signal Transduction Secretion	Exocytosis Secretion By Cell Secretion Intracellular Protein Transport Establishment Of Localization In Cell Cellular Localization Cellular Protein Localization Protein Transport Vesicle-mediated Transport Establishment Of Protein Localization Intracellular Transport Positive Regulation Of Secretion Protein Localization Regulation Of Exocytosis Regulation Of Secretion Positive Regulation Of Transport Transport Positive Regulation Of Exocytosis Regulation Of Vesicle-mediated Transport Deoxyhypusine Biosynthetic Process From Spermidine Granuloma Formation Spermidine Catabolic Process Multivesicular Body Sorting Pathway Peptidyl-lysine Modification To Peptidyl-hypusine Polyamine Catabolic Process Positive Regulation Of Protein Secretion Glucose Homeostasis Natural Killer Cell Degranulation Regulation Of Cellular Localization Chronic Inflammatory Response Positive Regulation Of Mucus Secretion Germinal Center Formation Positive Regulation Of Protein Transport Regulation Of Mucus Secretion Positive Regulation Of Regulated Secretory Pathway Regulation Of Protein Secretion Natural Killer Cell Activation Involved In Immune Response Natural Killer Cell Mediated Cytotoxicity Natural Killer Cell Mediated Immunity Regulation Of Mast Cell Degranulation Regulation Of Cell Activation Polyamine Metabolic Process Leukocyte Mediated Cytotoxicity Regulation Of Mast Cell Activation Melanocyte Differentiation Negative Regulation Of Insulin Secretion Regulation Of Regulated Secretory Pathway Melanosome Localization Leukocyte Degranulation Negative Regulation Of Peptide Secretion
Tagcloud ?		actively cargos controversy exocytosis granule granules granulomere gray jinx lacked lapse moved moves periphery platelets premise sort spread spreading subpopulation subpopulations timp2 translocated vamp vamps vefg von willebrand	7d autonomous biogenesis contributed deficient dicer disrupt exosomal exosome exosomes foxp3 helper intercellular interference let mechanistic micrornas mirna mirnas providing requirement silencing suppress suppressing suppression th1 transferred treg
Tagcloud (Difference) ?		actively cargos controversy exocytosis granule granules granulomere gray jinx lacked lapse moved moves periphery platelets premise sort spread spreading subpopulation subpopulations timp2 translocated vamp vamps vefg von willebrand	7d autonomous biogenesis contributed deficient dicer disrupt exosomal exosome exosomes foxp3 helper intercellular interference let mechanistic micrornas mirna mirnas providing requirement silencing suppress suppressing suppression th1 transferred treg
Tagcloud (Intersection) ?