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TRIM65 and TNRC6A
Number of citations of the paper that reports this interaction (PMID
24778252
)
0
Data Source:
BioGRID
(enzymatic study)
TRIM65
TNRC6A
Gene Name
tripartite motif containing 65
trinucleotide repeat containing 6A
Image
No pdb structure
No pdb structure
Gene Ontology Annotations
Cellular Component
Intracellular
Cytoplasmic MRNA Processing Body
Nucleoplasm
Cytosol
Micro-ribonucleoprotein Complex
Molecular Function
Zinc Ion Binding
Nucleotide Binding
Protein Binding
Poly(A) RNA Binding
Biological Process
Epidermal Growth Factor Receptor Signaling Pathway
Notch Signaling Pathway
Fibroblast Growth Factor Receptor Signaling Pathway
Cellular Response To Starvation
Gene Expression
Posttranscriptional Gene Silencing
Gene Silencing By MiRNA
Negative Regulation Of Translation Involved In Gene Silencing By MiRNA
Fc-epsilon Receptor Signaling Pathway
Innate Immune Response
Neurotrophin TRK Receptor Signaling Pathway
Phosphatidylinositol-mediated Signaling
Pathways
Signaling by the B Cell Receptor (BCR)
Signaling by FGFR in disease
PIP3 activates AKT signaling
Regulatory RNA pathways
Cellular Senescence
Signaling by Wnt
Signaling by EGFRvIII in Cancer
Oncogene Induced Senescence
Signaling by SCF-KIT
Downstream signaling events of B Cell Receptor (BCR)
DAP12 signaling
PI3K/AKT activation
PI-3K cascade
Pre-NOTCH Transcription and Translation
PI3K events in ERBB2 signaling
Downstream signaling of activated FGFR
Pre-NOTCH Expression and Processing
Post-transcriptional silencing by small RNAs
Innate Immune System
Signaling by PDGF
Transcriptional regulation by small RNAs
Signalling by NGF
DAP12 interactions
GAB1 signalosome
Signaling by NOTCH
Signaling by Ligand-Responsive EGFR Variants in Cancer
NGF signalling via TRKA from the plasma membrane
Signaling by ERBB4
Signaling by Overexpressed Wild-Type EGFR in Cancer
Role of LAT2/NTAL/LAB on calcium mobilization
PI3K events in ERBB4 signaling
Signaling by FGFR
beta-catenin independent WNT signaling
Signaling by ERBB2
Signaling by EGFR
Ca2+ pathway
Oxidative Stress Induced Senescence
Downstream signal transduction
Fc epsilon receptor (FCERI) signaling
Signaling by EGFR in Cancer
PI3K/AKT Signaling in Cancer
Adaptive Immune System
Drugs
Diseases
GWAS
White matter hyperintensity burden (
21681796
)
Type 2 diabetes (dietary heme iron intake interaction) (
23386860
)
Protein-Protein Interactions
9 interactors:
ANAPC11
MARCH7
MKRN3
RBCK1
SRPK1
TNRC6A
UBE2U
UBE2Z
UBE3A
7 interactors:
AGO4
CNOT6L
CNOT7
PAN2
TRIM65
TRIP13
WNK1
Entrez ID
201292
27327
HPRD ID
15569
11640
Ensembl ID
ENSG00000141569
ENSG00000090905
Uniprot IDs
Q6PJ69
Q8NDV7
PDB IDs
Enriched GO Terms of Interacting Partners
?
Protein Ubiquitination
Protein Modification By Small Protein Conjugation
Protein Polyubiquitination
Cellular Protein Modification Process
Cellular Protein Metabolic Process
Ubiquitin-dependent Protein Catabolic Process
Modification-dependent Protein Catabolic Process
Proteolysis Involved In Cellular Protein Catabolic Process
Cellular Protein Catabolic Process
Protein Catabolic Process
Protein Metabolic Process
Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process
Proteasomal Protein Catabolic Process
Cellular Macromolecule Catabolic Process
Sperm Entry
Regulation Of Protein Ubiquitination Involved In Ubiquitin-dependent Protein Catabolic Process
Viral Process
Protein Linear Polyubiquitination
Proteolysis
Regulation Of Protein Ubiquitination
Catabolic Process
Negative Regulation Of Translation Involved In Gene Silencing By MiRNA
Sperm Chromatin Condensation
Negative Regulation Of Necroptotic Process
Negative Regulation Of Necrotic Cell Death
Cellular Metabolic Process
Regulation Of Necroptotic Process
Nuclear-transcribed MRNA Poly(A) Tail Shortening
MRNA Catabolic Process
RNA Phosphodiester Bond Hydrolysis, Exonucleolytic
RNA Catabolic Process
Nuclear-transcribed MRNA Catabolic Process, Deadenylation-dependent Decay
Gene Silencing By RNA
MRNA 3'-end Processing
Gene Silencing
RNA 3'-end Processing
RNA Phosphodiester Bond Hydrolysis
Aromatic Compound Catabolic Process
MRNA Metabolic Process
Nuclear-transcribed MRNA Catabolic Process
Cellular Macromolecule Catabolic Process
Regulation Of Translation
Gene Silencing By MiRNA
Posttranscriptional Gene Silencing
Nucleic Acid Phosphodiester Bond Hydrolysis
MRNA Processing
Posttranscriptional Regulation Of Gene Expression
RNA Metabolic Process
RNA Processing
Gene Expression
Catabolic Process
Regulation Of Cellular Protein Metabolic Process
Regulation Of Protein Metabolic Process
Regulation Of Gene Expression, Epigenetic
Negative Regulation Of Pancreatic Juice Secretion
Positive Regulation Of Cytoplasmic MRNA Processing Body Assembly
Nucleobase-containing Compound Metabolic Process
Deadenylation-dependent Decapping Of Nuclear-transcribed MRNA
Heterocycle Metabolic Process
Cellular Aromatic Compound Metabolic Process
Regulation Of Cytoplasmic MRNA Processing Body Assembly
MRNA Destabilization
Cytoplasmic MRNA Processing Body Assembly
Cellular Nitrogen Compound Metabolic Process
Negative Regulation Of Translation Involved In Gene Silencing By MiRNA
Positive Regulation Of Nuclear-transcribed MRNA Poly(A) Tail Shortening
RNA Destabilization
Negative Regulation Of Gene Expression
Positive Regulation Of Systemic Arterial Blood Pressure
Nitrogen Compound Metabolic Process
Female Meiosis I
Positive Regulation Of MRNA 3'-end Processing
Positive Regulation Of Nuclear-transcribed MRNA Catabolic Process, Deadenylation-dependent Decay
Regulation Of MRNA 3'-end Processing
Positive Regulation Of MRNA Catabolic Process
Synaptonemal Complex Assembly
Cellular Metabolic Process
Tagcloud
?
arrest
bim
cdkn1a
cdkn1c
clusters
derepressed
derepression
disruption
endoderm
gt
gw182
lats1
lats2
microrna
mirna
mirnas
p21
p27
proper
pten
rb1
rbl
sac
selectively
silencing
suppression
targets
yolk
Tagcloud (Difference)
?
arrest
bim
cdkn1a
cdkn1c
clusters
derepressed
derepression
disruption
endoderm
gt
gw182
lats1
lats2
microrna
mirna
mirnas
p21
p27
proper
pten
rb1
rbl
sac
selectively
silencing
suppression
targets
yolk
Tagcloud (Intersection)
?