LRRC45 and CCDC89

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		LRRC45	CCDC89
Description		leucine rich repeat containing 45	coiled-coil domain containing 89
Image		No pdb structure
GO Annotations	Cellular Component	Cytoplasm Centrosome Cytosol Cytoskeleton Plasma Membrane Ciliary Basal Body	Nucleus Cytoplasm
	Molecular Function	Protein Binding	Protein Binding
	Biological Process
Pathways
Drugs
Diseases
GWAS		Neuroblastoma (pediatric) ( 32599975) Refractive error ( 32231278)	Age at first sexual intercourse ( 34211149) Refractive error ( 32231278)
Interacting Genes		10 interacting genes: ALAS1 CCDC89 KXD1 MCC MID2 SSX2 SSX2B SSX7 THAP11 ZDHHC17	5 interacting genes: BMPR2 FAM50B LRRC45 PIK3R3 TSFM
Entrez ID		201255	220388
HPRD ID		14476	08234
Ensembl ID		ENSG00000169683	ENSG00000179071
Uniprot IDs		Q96CN5	Q8N998
PDB IDs			8WQA 8WQB 8WQD 8WQH
Enriched GO Terms of Interacting Partners?			Positive Regulation Of Axon Extension Involved In Axon Guidance Negative Regulation Of Chondrocyte Proliferation Regulation Of Lung Blood Pressure Aortic Valve Development Lymphatic Endothelial Cell Differentiation BMP Receptor Activity Pulmonary Valve Development Tricuspid Valve Morphogenesis Venous Blood Vessel Development Negative Regulation Of Cell Proliferation Involved In Heart Valve Morphogenesis Negative Regulation Of Cell Proliferation Involved In Heart Morphogenesis Activin Receptor Activity, Type II Endochondral Bone Morphogenesis Transforming Growth Factor Beta Receptor Activity Semi-lunar Valve Development Mitral Valve Morphogenesis 1-phosphatidylinositol-3-kinase Regulator Activity Phosphatidylinositol 3-kinase Complex Mitochondrial Translational Elongation Maternal Placenta Development Lung Vasculature Development Pharyngeal Arch Artery Morphogenesis Endothelial Cell Apoptotic Process 1-phosphatidylinositol-3-kinase Activity Phosphatidylinositol 3-kinase Complex, Class IA Transmembrane Receptor Protein Serine/threonine Kinase Activity Negative Regulation Of Vasoconstriction Endocardial Cushion Development Intracellular Organelle Lumen Lymphangiogenesis Retina Vasculature Development In Camera-type Eye Regulation Of Axon Extension Involved In Axon Guidance Atrial Septum Morphogenesis
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