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NKX3-1 and TEX264
Number of citations of the paper that reports this interaction (PubMedID
18816836
)
45
Data Source:
BioGRID
(two hybrid)
NKX3-1
TEX264
Description
NK3 homeobox 1
testis expressed 264, ER-phagy receptor
Image
GO Annotations
Cellular Component
Chromatin
Nucleus
Nucleoplasm
Cytosol
Site Of DNA Damage
Autophagosome Membrane
Extracellular Region
Nucleus
Replication Fork
Chromosome
Cytoplasm
Autophagosome
Endoplasmic Reticulum
Endoplasmic Reticulum Membrane
Cytosol
Membrane
Platelet Alpha Granule Lumen
Cytoplasmic Vesicle
Molecular Function
Transcription Cis-regulatory Region Binding
RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding
DNA-binding Transcription Factor Activity, RNA Polymerase II-specific
DNA Binding
DNA-binding Transcription Factor Activity
Nuclear Receptor Activity
Protein Binding
Cysteine-type Endopeptidase Activator Activity Involved In Apoptotic Process
Nuclear Estrogen Receptor Binding
Histone Deacetylase Binding
Sequence-specific DNA Binding
MADS Box Domain Binding
DNA-binding Transcription Factor Binding
Transcription Regulator Inhibitor Activity
Sequence-specific Double-stranded DNA Binding
Protein Binding
Signaling Receptor Activity
Biological Process
Negative Regulation Of Transcription By RNA Polymerase II
Urogenital System Development
Metanephros Development
Somitogenesis
Regulation Of DNA-templated Transcription
Regulation Of Transcription By RNA Polymerase II
Apoptotic Process
DNA Damage Response
Salivary Gland Development
Heart Development
Positive Regulation Of Cell Population Proliferation
Negative Regulation Of Cell Population Proliferation
Male Gonad Development
Regulation Of Signal Transduction
Positive Regulation Of Gene Expression
Negative Regulation Of Gene Expression
Cell Differentiation
Androgen Receptor Signaling Pathway
Prostate Gland Development
Regulation Of Protein Localization
Response To Testosterone
Response To Lipid
Dorsal Aorta Development
Regulation Of Cell Population Proliferation
Negative Regulation Of Insulin-like Growth Factor Receptor Signaling Pathway
Negative Regulation Of DNA-templated Transcription
Positive Regulation Of DNA-templated Transcription
Positive Regulation Of Mitotic Cell Cycle
Positive Regulation Of Transcription By RNA Polymerase II
Branching Morphogenesis Of An Epithelial Tube
Epithelial Cell Proliferation
Negative Regulation Of Epithelial Cell Proliferation
Regulation Of Multicellular Organismal Process
Positive Regulation Of Cell Division
Positive Regulation Of Phosphatidylinositol 3-kinase/protein Kinase B Signal Transduction
Pharyngeal System Development
Branching Involved In Prostate Gland Morphogenesis
Epithelial Cell Proliferation Involved In Salivary Gland Morphogenesis
Epithelial Cell Proliferation Involved In Prostate Gland Development
Negative Regulation Of Epithelial Cell Proliferation Involved In Prostate Gland Development
Cellular Response To Interleukin-1
Cellular Response To Tumor Necrosis Factor
Cellular Response To Steroid Hormone Stimulus
Cellular Response To Hypoxia
Cellular Response To Xenobiotic Stimulus
Positive Regulation Of Androgen Secretion
Positive Regulation Of Intrinsic Apoptotic Signaling Pathway
DNA Repair
Autophagy
DNA Damage Response
Reticulophagy
Protein-DNA Covalent Cross-linking Repair
Pathways
Platelet degranulation
Drugs
Diseases
Prostate cancer
GWAS
Birth weight (
31043758
)
Mean corpuscular hemoglobin (
29403010
)
Mean corpuscular hemoglobin concentration (
29403010
)
Prostate cancer (
26443449
32986714
34012061
)
Prostate-specific antigen levels (
28139693
)
Waist-hip ratio (
25673412
)
Waist-to-hip ratio adjusted for BMI (age <50) (
26426971
)
Waist-to-hip ratio adjusted for BMI (age >50) (
26426971
)
Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) (
26426971
)
Interacting Genes
38 interacting genes:
AEN
CCT7
CD200R1L
CENPX
CHPF
CKAP4
FEM1B
HIPK2
HMG20B
HNRNPA0
HSP90B1
LMCD1
MAN2B1
MNAT1
MRE11
MT-ND4
PEBP1
PTMS
RABL6
RARG
RHOXF2
RNF4
RPL37A
RPSA
SLC67A1
SP1
SP2
SP3
SP4
SP5
SPDEF
SRF
STMN3
TEX264
TOPORS
TPT1
WDR77
ZNF417
28 interacting genes:
ADGRG3
ARL13B
CERS4
CLDN2
CLN6
COQ9
CREB3L1
EMP1
FAM209A
FFAR2
FFAR3
GABARAPL2
GJB1
GPR152
GPR42
LHFPL4
LHFPL5
MFF
MS4A3
NKX3-1
OPRM1
SLC10A2
SLC34A2
SMIM3
TM4SF18
TMEM31
TMEM79
TSPAN12
Entrez ID
4824
51368
HPRD ID
03620
15492
Ensembl ID
ENSG00000167034
ENSG00000164081
Uniprot IDs
Q99801
A0A087WTU3
Q9Y6I9
PDB IDs
2L9R
7VEC
7VED
Enriched GO Terms of Interacting Partners
?
Nucleus
DNA Binding
PML Body
Nucleoplasm
Regulation Of Nucleobase-containing Compound Metabolic Process
Regulation Of Transcription By RNA Polymerase II
Trachea Cartilage Development
Sequence-specific Double-stranded DNA Binding
Embryonic Eye Morphogenesis
Glandular Epithelial Cell Development
Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage By P53 Class Mediator
Sequence-specific DNA Binding
Chromatin
DNA-binding Transcription Factor Activity, RNA Polymerase II-specific
Regulation Of RNA Metabolic Process
Regulation Of DNA-templated Transcription
Regulation Of Primary Metabolic Process
Regulation Of RNA Biosynthetic Process
Regulation Of Apoptotic Process
Double-stranded DNA Binding
Regulation Of Programmed Cell Death
DNA Damage Response
Intrinsic Apoptotic Signaling Pathway By P53 Class Mediator
Eye Morphogenesis
Negative Regulation Of Nucleobase-containing Compound Metabolic Process
Sensory Organ Morphogenesis
Columnar/cuboidal Epithelial Cell Development
Embryonic Camera-type Eye Morphogenesis
Zinc Ion Binding
Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage
Trophectodermal Cell Differentiation
Negative Regulation Of RNA Metabolic Process
Regulation Of Macromolecule Metabolic Process
RNA Polymerase II-specific DNA-binding Transcription Factor Binding
Positive Regulation Of Nucleobase-containing Compound Metabolic Process
Face Development
Regulation Of Macromolecule Biosynthetic Process
Prostate Gland Epithelium Morphogenesis
RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding
Macromolecule Metabolic Process
Signal Transduction By P53 Class Mediator
Cellular Response To Stress
Replication Fork
Positive Regulation Of Macromolecule Metabolic Process
Mitochondrial Double-strand Break Repair Via Homologous Recombination
Negative Regulation Of DNA-templated Transcription
Negative Regulation Of RNA Biosynthetic Process
Positive Regulation Of Hydrogen Sulfide Biosynthetic Process
Cellular Response To Wortmannin
Thyroid Gland Development
Membrane
Positive Regulation Of Acute Inflammatory Response To Non-antigenic Stimulus
Mucosal Immune Response
Organ Or Tissue Specific Immune Response
G Protein-coupled Receptor Activity
Adenylate Cyclase-inhibiting G Protein-coupled Receptor Signaling Pathway
GABA Receptor Binding
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Tagcloud (Difference)
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Tagcloud (Intersection)
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