FAM209A and LHFPL5

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		FAM209A	LHFPL5
Description		family with sequence similarity 209 member A	LHFPL tetraspan subfamily member 5
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Nuclear Inner Membrane Membrane Extracellular Exosome	Plasma Membrane Membrane Apical Plasma Membrane Stereocilium Bundle Stereocilium Tip
	Molecular Function	Protein Binding	Protein Binding
	Biological Process	Spermatogenesis Cell Differentiation	Monoatomic Ion Transport Sensory Perception Of Sound Detection Of Mechanical Stimulus Involved In Sensory Perception Of Sound Detection Of Mechanical Stimulus Involved In Sensory Perception Auditory Receptor Cell Stereocilium Organization
Pathways			Sensory processing of sound by inner hair cells of the cochlea Sensory processing of sound by outer hair cells of the cochlea
Drugs
Diseases
GWAS		Heschl's gyrus morphology ( 25130324)	Eosinophil count ( 32888494) Eosinophil percentage of white cells ( 32888494) High light scatter reticulocyte count ( 32888494) High light scatter reticulocyte percentage of red cells ( 32888494) Hip circumference adjusted for BMI ( 34021172) Immature fraction of reticulocytes ( 32888494)
Interacting Genes		258 interacting genes: ADGRE2 ADIPOQ AGTRAP AIG1 ALG8 ANKRD46 APMAP APOC3 APOD APOL2 APOL3 AQP1 AQP2 AQP3 ARLN ARV1 ASGR1 ATP13A1 B4GALNT2 BDNF BET1 BIK BMP10 BNIP2 BNIP3 BTN2A2 C11orf24 C14orf180 C1GALT1 C2 C3orf52 CANT1 CCL4L2 CD53 CD59 CD81 CDIPT CDS1 CDS2 CLCA4 CLDN19 CLDN2 CLDN4 CLDND2 CLEC4G CLN6 CMTM7 CNIH1 CNPY3 COL4A5 COL8A2 COMT CTRL CTSA CTXN3 CXCL16 CYB561 CYB561D2 CYB5B CYBC1 DEFB121 DEFB128 DNAJC30 DOLK EBP EMC6 EMD ENTPD3 EOGT ERG28 ERMP1 FA2H FAM20B FAM3C FATE1 FCER1G FDFT1 FIS1 FUNDC2 FXYD3 FXYD6 GAST GET3 GHITM GIMAP1 GIMAP5 GJB2 GKN1 GKN2 GOSR2 GPR108 GPR151 GPR152 GPR37L1 GYPA HACD2 HHATL HMOX1 HMOX2 HTATIP2 IGFBP5 INSIG2 JAGN1 KIR2DL3 LAT LHFPL5 LPAR3 LRP10 MAL MARCHF2 MFF MFSD6 MGLL MIP MMD MMD2 MS4A1 MS4A13 MYADM MYADML2 NAPB NAT8 NCR3 NINJ2 NKG7 NRM NXPE3 OLFM4 ORMDL1 ORMDL3 OTOR PAQR7 PEDS1-UBE2V1 PEX16 PGAP2 PGLYRP3 PLLP PLN PLP1 PLP2 PLPP4 PLPP6 PMP22 PNLIPRP1 PRB1 PTCH1 RHAG RPRM RTP2 RUSF1 S100A2 SACM1L SCARF1 SCD SCGB1D1 SCRG1 SEC22A SEC22B SEC61G SELENOK SEMA6C SERP1 SFTPC SLC13A3 SLC1A1 SLC30A8 SLC35A1 SLC35A4 SLC35B4 SLC35E3 SLC35G2 SLC38A7 SLC39A2 SLC41A1 SLC52A2 SLC7A14 SMAGP SMCO4 SMIM1 SNORC STATH STRIT1 STX12 STX1B STX3 STX5 STX8 SYNGR1 SYT15 SYT15B TECR TEX264 TF TFRC THBD THSD7B TM6SF2 TMBIM6 TMEM100 TMEM107 TMEM11 TMEM120A TMEM128 TMEM140 TMEM141 TMEM147 TMEM14A TMEM14B TMEM14C TMEM203 TMEM208 TMEM218 TMEM222 TMEM229B TMEM236 TMEM239 TMEM243 TMEM254 TMEM42 TMEM43 TMEM47 TMEM50B TMEM60 TMEM65 TMEM72 TMEM79 TMEM86A TMEM86B TMEM97 TMPRSS4 TMUB2 TNF TNFRSF10C TNMD TRAF3IP3 TRAM1L1 TRARG1 TREX1 TSPAN2 TSPAN33 TSPAN7 TSPO TWSG1 UBE2J1 UBIAD1 UNC50 UPK1B VAMP3 VAMP4 VAMP5 VKORC1 VMP1 VSTM1 WFDC2 WFS1 YIPF4 YIPF6 ZFPL1	131 interacting genes: ADGRG3 APOL3 AQP2 AQP6 AQP9 ARL13B BTN2A2 C14orf180 C1GALT1 C3orf52 C5orf46 CD37 CD53 CD72 CD79A CD81 CDS2 CERS4 CLCN7 CLDN22 CLDN5 CLDND2 CLEC14A CMTM7 CPLX4 CREB3 CREB3L1 CTXN3 CXCL16 CYB561 DAGLA ELOVL4 EMP1 EMP3 ENTPD3 ERG28 ERGIC3 FAM209A FCGR1A FFAR2 FNDC9 FXYD6 GJA8 GJB2 GJB3 GJB4 GJB6 GPR152 GPR37L1 GPR42 GPRC5D GPX8 HAS3 HLA-DQA2 HSD17B13 INSIG2 ITGB2 JAGN1 KASH5 KCNK5 KIR2DL3 KTN1 LAT LIME1 LMNA LNPEP LPAR3 LRRC25 LRRC4C MFF MIP MS4A13 MTIF3 NINJ2 NIPAL4 NKG7 NRG4 PDZK1IP1 PLLP PLP1 PLP2 RMDN3 RPRM RUSF1 SAR1A SCN3B SEC22A SEC22B SERP1 SERP2 SERTM1 SLC16A2 SLC34A2 SLC35A1 SLC35B4 SLC35H1 SLC41A1 SLC61A1 SMIM1 SSMEM1 SYNJ2BP TEX264 TFRC TIMMDC1 TM4SF18 TM4SF4 TMEM100 TMEM107 TMEM128 TMEM201 TMEM218 TMEM229B TMEM248 TMEM254 TMEM31 TMEM42 TMEM50B TMEM52B TMEM60 TMEM86A TMEM97 TMX1 TMX2 TRARG1 TSPAN33 TSPAN7 TSPO UBIAD1 VAMP3 VMA21 ZDHHC15
Entrez ID		200232	222662
HPRD ID		18536	13989
Ensembl ID		ENSG00000124103	ENSG00000197753
Uniprot IDs		Q5JX71	Q8TAF8
PDB IDs
Enriched GO Terms of Interacting Partners?		Membrane Endoplasmic Reticulum Membrane Endoplasmic Reticulum Protein Binding SNAP Receptor Activity Plasma Membrane SNARE Complex Golgi Apparatus Chemical Homeostasis Golgi Membrane Membrane Organization Vesicle Fusion Endomembrane System Endoplasmic Reticulum-Golgi Intermediate Compartment Membrane Cellular Response To Mercury Ion Organelle Membrane Fusion Membrane Fusion Organelle Fusion Lipid Metabolic Process Localization Within Membrane Cholesterol Binding Multicellular Organismal-level Chemical Homeostasis Establishment Of Protein Localization To Membrane Lipid Biosynthetic Process Intracellular Chemical Homeostasis Vesicle-mediated Transport Sterol Biosynthetic Process Establishment Of Protein Localization Water Channel Activity SNARE Binding Membrane Docking Regulation Of ATPase-coupled Calcium Transmembrane Transporter Activity Protein Localization To Membrane Ankyrin-1 Complex Glycerol Transmembrane Transport Paracellular Transport Nuclear Inner Membrane Sterol Metabolic Process Response To Bacterium Renal Water Transport Renal Water Homeostasis Intracellular Monoatomic Ion Homeostasis Heme Metabolic Process Protein Localization To Cell Periphery Organelle Localization By Membrane Tethering Glycerol Transmembrane Transporter Activity Phosphatidate Cytidylyltransferase Activity Cholesterol Biosynthetic Process Heme Oxidation Heme Oxygenase (decyclizing) Activity	Membrane Protein Binding Plasma Membrane Gap Junction-mediated Intercellular Transport Intercellular Transport Connexin Complex Endoplasmic Reticulum Membrane Endoplasmic Reticulum Gap Junction Channel Activity Gap Junction Water Channel Activity Water Transport Bleb Assembly Pyrimidine Nucleotide-sugar Transmembrane Transport Nucleotide-sugar Transmembrane Transport Transmembrane Transport Fluid Transport Channel Activity B Cell Receptor Complex Gap Junction Channel Activity Involved In Cell Communication By Electrical Coupling Immunological Synapse
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