EFNA5 and EPHA5

Number of citations of the paper that reports this interaction (PMID 10531456)
13

Data Source:
HPRD (in vivo)

		EFNA5	EPHA5
Gene Name		ephrin-A5	EPH receptor A5
Image
Gene Ontology Annotations	Cellular Component	Extracellular Region Plasma Membrane Caveola Anchored Component Of External Side Of Plasma Membrane	Rough Endoplasmic Reticulum Plasma Membrane Integral Component Of Plasma Membrane External Side Of Plasma Membrane Axon Dendrite Neuronal Cell Body Perinuclear Region Of Cytoplasm
	Molecular Function	Chemorepellent Activity Ephrin Receptor Binding	Ephrin Receptor Activity GPI-linked Ephrin Receptor Activity Transmembrane-ephrin Receptor Activity ATP Binding
	Biological Process	Apoptotic Process Nervous System Development Axon Guidance Regulation Of Cell-cell Adhesion Retinal Ganglion Cell Axon Guidance Regulation Of Rac GTPase Activity Regulation Of Rho GTPase Activity Regulation Of Actin Cytoskeleton Organization Ephrin Receptor Signaling Pathway Positive Regulation Of Peptidyl-tyrosine Phosphorylation Negative Chemotaxis Regulation Of Focal Adhesion Assembly Regulation Of Insulin Secretion Involved In Cellular Response To Glucose Stimulus Regulation Of Microtubule Cytoskeleton Organization	Axon Guidance Peptidyl-tyrosine Phosphorylation CAMP-mediated Signaling Hippocampus Development Regulation Of Rac GTPase Activity Positive Regulation Of CREB Transcription Factor Activity Regulation Of Actin Cytoskeleton Organization Ephrin Receptor Signaling Pathway Neuron Development Regulation Of Insulin Secretion Involved In Cellular Response To Glucose Stimulus
Pathways		EPHA-mediated growth cone collapse EPH-ephrin mediated repulsion of cells Axon guidance EPH-Ephrin signaling	EPHA-mediated growth cone collapse EPH-ephrin mediated repulsion of cells Axon guidance EPH-Ephrin signaling
Drugs
Diseases
GWAS		Alzheimer's disease biomarkers ( 23419831) Hippocampal atrophy ( 19668339)	HIV-1 viral setpoint ( 22174851)
Protein-Protein Interactions		10 interactors: EPHA2 EPHA3 EPHA4 EPHA5 EPHA7 EPHA8 EPHB1 EPHB2 GRIP1 SRC	6 interactors: EFNA1 EFNA2 EFNA3 EFNA4 EFNA5 NEDD4
Entrez ID		1946	2044
HPRD ID		03324	02474
Ensembl ID		ENSG00000184349	ENSG00000145242
Uniprot IDs		P52803	B7ZKJ3 B7ZKW7 F8VP57 F8W9W0 P54756 Q59FT4
PDB IDs		2X11 3MX0 4BK5 4BKA	2R2P 4ET7
Enriched GO Terms of Interacting Partners?		Ephrin Receptor Signaling Pathway Peptidyl-tyrosine Phosphorylation Axon Guidance Neuron Projection Development Neuron Development Axonogenesis Axon Development Cell Morphogenesis Involved In Neuron Differentiation Chemotaxis Neuron Differentiation Neuron Projection Morphogenesis Cell Projection Organization Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Cell Morphogenesis Involved In Differentiation Cell Projection Morphogenesis Cell Part Morphogenesis Enzyme Linked Receptor Protein Signaling Pathway Generation Of Neurons Peptidyl-amino Acid Modification Neurogenesis Cell Morphogenesis Cell Development Locomotion Protein Phosphorylation Nervous System Development Movement Of Cell Or Subcellular Component Response To External Stimulus Phosphorylation Cell Differentiation Anatomical Structure Morphogenesis System Development Regulation Of Intracellular Signal Transduction Retinal Ganglion Cell Axon Guidance Phosphate-containing Compound Metabolic Process Regulation Of MAPK Cascade Axonal Fasciculation Regulation Of Signaling Cell Surface Receptor Signaling Pathway Multicellular Organismal Development Cellular Protein Modification Process Fasciculation Of Motor Neuron Axon Anatomical Structure Development Signal Transduction Neuron Recognition Central Nervous System Projection Neuron Axonogenesis Cell Migration Fasciculation Of Sensory Neuron Axon Developmental Process Cell Motility Signaling	Ephrin Receptor Signaling Pathway Neuron Projection Development Neuron Development Axon Guidance Neuron Differentiation Cell Projection Organization Locomotion Axonogenesis Axon Development Cell Morphogenesis Involved In Neuron Differentiation Chemotaxis Neuron Projection Morphogenesis Generation Of Neurons Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Neurogenesis Cell Morphogenesis Involved In Differentiation Cell Development Cell Projection Morphogenesis Cell Part Morphogenesis Enzyme Linked Receptor Protein Signaling Pathway Nervous System Development Cell Morphogenesis Anatomical Structure Morphogenesis Cell Surface Receptor Signaling Pathway Movement Of Cell Or Subcellular Component Cell Differentiation Response To External Stimulus Cell-cell Signaling System Development Osteoclast Differentiation Multicellular Organismal Development Anatomical Structure Development Bone Remodeling Signal Transduction Regulation Of Dendrite Morphogenesis Developmental Process Signaling Cell Communication Negative Regulation Of Transcription From RNA Polymerase II Promoter In Response To UV-induced DNA Damage Transmission Of Virus Development Involved In Symbiotic Interaction Regulation Of Dendrite Development Tissue Remodeling Myeloid Leukocyte Differentiation Cellular Response To Stimulus Positive Regulation Of Peptidyl-tyrosine Phosphorylation Negative Regulation Of Dendritic Spine Morphogenesis Endocardial Cushion To Mesenchymal Transition Involved In Heart Valve Formation Mesenchyme Development Regulation Of Peptidyl-tyrosine Phosphorylation
Tagcloud ?		adni apoe apolipoprotein arid1b bche butyrylcholinesterase c12orf75 cortical edil3 florbetapir gwas initiative itga1 itga6 largest load modifying neuroimaging nfib noninvasive nuak1 pik3r1 pivotal positron prohibited rs429358 rs509208 senile suggestive	aurka aurkb bioinformatics cdkn2a copy custom describing flt4 frameshift insertions interrogating kdm6a leiomyosarcomas locally losses map2k4 multiplexed nf1 ngs notch1 pdgfrb pik3ca pipeline rationale rb1 sarcomas soft stratification targetable
Tagcloud (Difference) ?		adni apoe apolipoprotein arid1b bche butyrylcholinesterase c12orf75 cortical edil3 florbetapir gwas initiative itga1 itga6 largest load modifying neuroimaging nfib noninvasive nuak1 pik3r1 pivotal positron prohibited rs429358 rs509208 senile suggestive	aurka aurkb bioinformatics cdkn2a copy custom describing flt4 frameshift insertions interrogating kdm6a leiomyosarcomas locally losses map2k4 multiplexed nf1 ngs notch1 pdgfrb pik3ca pipeline rationale rb1 sarcomas soft stratification targetable
Tagcloud (Intersection) ?