PGAM5 and MIR107

Number of citations of the paper that reports this interaction (PubMedID 28431233)
0

Data Source:
BioGRID (unspecified method)

		PGAM5	MIR107
Description		PGAM family member 5, mitochondrial serine/threonine protein phosphatase	microRNA 107
Image			No pdb structure
GO Annotations	Cellular Component	Mitochondrion Mitochondrial Outer Membrane Mitochondrial Inner Membrane Membrane	Extracellular Space RISC Complex Neuronal Cell Body Extracellular Vesicle
	Molecular Function	Protein Serine/threonine Phosphatase Activity Protein Binding Hydrolase Activity	MRNA Base-pairing Post-transcriptional Repressor Activity
	Biological Process	Programmed Cell Death Macroautophagy Necroptotic Process Positive Regulation Of Mitochondrial Fission Negative Regulation Of Cold-induced Thermogenesis	Cellular Response To Insulin Stimulus MiRNA-mediated Post-transcriptional Gene Silencing MiRNA-mediated Gene Silencing By Inhibition Of Translation Negative Regulation Of Fat Cell Differentiation Positive Regulation Of Gluconeogenesis Negative Regulation Of D-glucose Import Negative Regulation Of Insulin Receptor Signaling Pathway Positive Regulation Of Necroptotic Process Cellular Response To Hydrogen Peroxide Negative Regulation Of Amyloid Precursor Protein Catabolic Process Negative Regulation Of Vascular Endothelial Growth Factor Production
Pathways
Drugs
Diseases
GWAS		Mean corpuscular hemoglobin ( 32888494) Mean reticulocyte volume ( 32888494) Mean spheric corpuscular volume ( 32888494)
Interacting Genes		32 interacting genes: HSPA1B MIR106A MIR106B MIR107 MIR10B MIR128-1 MIR141 MIR145 MIR15A MIR16-1 MIR18B MIR200B MIR205 MIR206 MIR20B MIR21 MIR214 MIR25 MIR34A MIR451A MIR93 MIRLET7A1 MIRLET7A2 MIRLET7B MIRLET7E MIRLET7F1 RNF5 SETDB1 UBE4B XIAP YWHAG ZBTB16	83 interacting genes: AIMP1 AIMP2 AQR C1QBP CDC5L CELF1 CPSF1 DARS1 DDX1 DDX21 DDX3X DDX3Y DHX36 DHX37 EDC4 EIF2AK2 EPRS1 ERAL1 FAM98A FUS G3BP2 HNRNPA0 HNRNPA1 HNRNPA2B1 HNRNPA3 HNRNPF HNRNPH1 HNRNPH2 HNRNPH3 HNRNPK HNRNPL HNRNPM HNRNPR IARS1 IGF2BP1 IGF2BP2 IGF2BP3 KARS1 LARP7 LARS1 LIN28A LIN28B LRPPRC MARS1 MATR3 NOL6 NONO NUDT21 NUFIP2 P3H1 PDCD11 PGAM5 PRMT1 PTBP1 PTBP3 PUF60 PUM1 QARS1 RARS1 RBFOX2 RBM10 RBM14 RBM17 RTCB SF3A1 SF3A3 SF3B1 SF3B2 SF3B3 SF3B4 SFPQ SUGP2 SYMPK SYNCRIP TAF15 TRA2A TRA2B U2SURP UPF1 UTP20 YBX1 YBX3 ZNF346
Entrez ID		192111	406901
HPRD ID		14681
Ensembl ID		ENSG00000247077	ENSG00000198997
Uniprot IDs		A0A994J4Y8 Q96HS1
PDB IDs		3MXO 3O0T 5MUF 6CNI 6CNL 7QAL 7QAM 7QAO 7QAP 8IN0
Enriched GO Terms of Interacting Partners?		MRNA Base-pairing Post-transcriptional Repressor Activity MiRNA-mediated Post-transcriptional Gene Silencing Regulatory NcRNA-mediated Post-transcriptional Gene Silencing Post-transcriptional Gene Silencing RISC Complex Regulatory NcRNA-mediated Gene Silencing Post-transcriptional Regulation Of Gene Expression Negative Regulation Of Gene Expression MRNA 3'-UTR Binding MiRNA-mediated Gene Silencing By Inhibition Of Translation MiRNA-mediated Gene Silencing By MRNA Destabilization Negative Regulation Of Macromolecule Biosynthetic Process Negative Regulation Of Biosynthetic Process Negative Regulation Of Metabolic Process Negative Regulation Of Macromolecule Metabolic Process Extracellular Vesicle Negative Regulation Of Translation Negative Regulation Of Cytokine Production MRNA Destabilization Negative Regulation Of Vascular Endothelial Growth Factor Production RNA Destabilization Positive Regulation Of MRNA Catabolic Process Positive Regulation Of MRNA Metabolic Process Regulation Of Translation Negative Regulation Of Cell Migration Regulation Of Cytokine Production Negative Regulation Of Cell Motility Regulation Of MRNA Stability Negative Regulation Of Locomotion Negative Regulation Of Protein Metabolic Process Regulation Of RNA Stability Regulation Of Gene Expression Regulation Of Macromolecule Biosynthetic Process Negative Regulation Of Multicellular Organismal Process Negative Regulation Of Signal Transduction Regulation Of Vascular Endothelial Growth Factor Production Negative Regulation Of Angiogenesis Negative Regulation Of Vasculature Development Negative Regulation Of Cell Communication Negative Regulation Of Signaling Negative Regulation Of Developmental Process Regulation Of Metabolic Process Regulation Of Macromolecule Metabolic Process Regulation Of Angiogenesis Regulation Of MRNA Metabolic Process Regulation Of Vasculature Development Regulation Of Cellular Response To Growth Factor Stimulus Negative Regulation Of Endothelial Cell Migration Regulation Of Blood Vessel Endothelial Cell Migration Regulation Of Multicellular Organismal Process	RNA Binding Nucleic Acid Binding RNA Processing RNA Metabolic Process RNA Splicing MRNA Processing Nucleic Acid Metabolic Process MRNA Metabolic Process Nucleobase-containing Compound Metabolic Process MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions Macromolecule Metabolic Process Regulation Of MRNA Metabolic Process MRNA Binding Spliceosomal Complex Regulation Of RNA Splicing Nucleoplasm Aminoacyl-tRNA Synthetase Multienzyme Complex Nucleus Catalytic Step 2 Spliceosome Ribonucleoprotein Complex Post-transcriptional Regulation Of Gene Expression Negative Regulation Of MRNA Metabolic Process Regulation Of MRNA Processing Regulation Of MRNA Splicing, Via Spliceosome Cytoplasmic Stress Granule Negative Regulation Of RNA Catabolic Process MRNA 3'-UTR Binding Regulation Of RNA Stability MiRNA Binding Negative Regulation Of MRNA Catabolic Process RNA Stabilization Regulation Of MRNA Stability MRNA Stabilization Regulation Of Translation TRNA Aminoacylation For Protein Translation Aminoacyl-tRNA Ligase Activity TRNA Aminoacylation U2 SnRNP Positive Regulation Of Gene Expression Regulation Of Gene Expression Negative Regulation Of Translation Positive Regulation Of Cytoplasmic Translation Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Macromolecule Biosynthetic Process Negative Regulation Of Macromolecule Metabolic Process Regulation Of Macromolecule Metabolic Process Negative Regulation Of Metabolic Process CRD-mediated MRNA Stabilization Positive Regulation Of Biosynthetic Process
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