TOR1AIP2 and TOR1A

Number of citations of the paper that reports this interaction (PubMedID 15767459)
22

Data Source:
HPRD (in vivo)

		TOR1AIP2	TOR1A
Description		torsin 1A interacting protein 2	torsin family 1 member A
Image
GO Annotations	Cellular Component	Nucleus Endoplasmic Reticulum Endoplasmic Reticulum Membrane Endomembrane System Membrane Nuclear Membrane	Nucleus Nuclear Envelope Cytoplasm Endoplasmic Reticulum Endoplasmic Reticulum Lumen Endoplasmic Reticulum Membrane Cytosol Cytoskeleton Synaptic Vesicle Endomembrane System Membrane Transport Vesicle Secretory Granule Growth Cone Cytoplasmic Vesicle Membrane Cytoplasmic Vesicle Nuclear Membrane Cell Projection Synapse Extracellular Exosome
	Molecular Function	ATPase Activator Activity Protein Binding ATPase Binding	Nucleotide Binding Protein Binding ATP Binding Cytoskeletal Protein Binding Hydrolase Activity ATP Hydrolysis Activity Kinesin Binding Identical Protein Binding Unfolded Protein Binding Misfolded Protein Binding ATP-dependent Protein Folding Chaperone
	Biological Process	Endoplasmic Reticulum Organization Positive Regulation Of ATP-dependent Activity Membrane Organization Protein Localization To Nuclear Envelope	Protein Deneddylation Protein Folding Response To Oxidative Stress Nuclear Envelope Organization Cell Adhesion Neuron Projection Development Protein Localization To Nucleus ERAD Pathway Wound Healing, Spreading Of Cells Intermediate Filament Cytoskeleton Organization Synaptic Vesicle Transport Synaptic Vesicle Membrane Organization Regulation Of Dopamine Uptake Involved In Synaptic Transmission Nuclear Membrane Organization Positive Regulation Of Synaptic Vesicle Endocytosis Regulation Of Protein Localization To Cell Surface
Pathways			Cargo recognition for clathrin-mediated endocytosis
Drugs
Diseases			Primary torsion dystonia (PTD)
GWAS		Refractive error ( 32231278)	Prostate cancer ( 29892016) Prostate cancer (advanced) ( 29892016) Prostate cancer (early onset) ( 29892016)
Interacting Genes		7 interacting genes: OGT RBPMS TOR1A TRIM55 TRIM63 UBC WEE2-AS1	7 interacting genes: KRTAP10-7 LMNA LRRC7 MDFI SNCA TOR1AIP2 TOR1B
Entrez ID		163590	1861
HPRD ID		10048	06897
Ensembl ID		ENSG00000169905	ENSG00000136827
Uniprot IDs		A0A6B9D1Q5 Q8NFQ8 Q9H496	B3KPA1 O14656
PDB IDs		5J1S 5J1T	5J1S 5J1T 6OIF
Enriched GO Terms of Interacting Partners?		Protein Modification Process Post-translational Protein Modification Regulation Of Glycolytic Process Protein N-acetylglucosaminyltransferase Complex Negative Regulation Of Non-canonical Inflammasome Complex Assembly Regulation Of Carbohydrate Catabolic Process Regulation Of ATP Metabolic Process Regulation Of Purine Nucleotide Metabolic Process Response To Electrical Stimulus Involved In Regulation Of Muscle Adaptation Regulation Of Generation Of Precursor Metabolites And Energy Protein O-acetylglucosaminyltransferase Activity Positive Regulation Of Synaptic Vesicle Endocytosis Positive Regulation Of Synaptic Vesicle Recycling Protein Metabolic Process Protein Ubiquitination Protein Modification By Small Protein Conjugation Positive Regulation Of Transcription From RNA Polymerase II Promoter By Glucose Non-canonical Inflammasome Complex Assembly Positive Regulation Of Transcription By Glucose Carbon Catabolite Regulation Of Transcription Regulation Of Transcription From RNA Polymerase II Promoter By Glucose MRNA CDS Binding Diapedesis Skeletal Muscle Atrophy Skeletal Muscle Adaptation Striated Muscle Atrophy Pre-mRNA 5'-splice Site Binding Regulation Of Dopamine Uptake Involved In Synaptic Transmission Response To Stress MRNA 5'-splice Site Recognition Regulation Of Transcription By Glucose Muscle Atrophy Protein Deneddylation NSL Complex	Protein Localization To Nucleus Protein Localization To Nuclear Envelope Membrane Organization Protein Localization To Organelle Negative Regulation Of Muscle Hypertrophy Cardiac Cell Development Nuclear Membrane Identical Protein Binding Negative Regulation Of Cardiac Muscle Hypertrophy Protein Sequestering Activity Notch Signaling Pathway Involved In Regulation Of Secondary Heart Field Cardioblast Proliferation Venous Endothelial Cell Differentiation Negative Regulation Of Exocytosis Coronary Sinus Valve Morphogenesis Enzyme Inhibitor Activity Foregut Morphogenesis Negative Regulation Of Sperm Capacitation Alkylglycerophosphoethanolamine Phosphodiesterase Activity Response To Desipramine Negative Regulation Of Norepinephrine Uptake Phospholipase D Inhibitor Activity Positive Regulation Of SNARE Complex Assembly Negative Regulation Of Dopamine Uptake Involved In Synaptic Transmission Kinesin Binding Endoplasmic Reticulum Organization Protein-containing Complex Localization DNA Double-strand Break Attachment To Nuclear Envelope Regulation Of Cardiac Muscle Hypertrophy Structural Constituent Of Nuclear Lamina Axis Specification Notch Signaling Involved In Heart Development Endocardium Morphogenesis Mitral Valve Formation Positive Regulation Of Aorta Morphogenesis Coronary Vein Morphogenesis Negative Regulation Of Cell Proliferation Involved In Heart Valve Morphogenesis Cardiac Right Atrium Morphogenesis Regulation Of Norepinephrine Uptake Negative Regulation Of Mitochondrial Electron Transport, NADH To Ubiquinone Positive Regulation Of Hydrogen Peroxide Catabolic Process Establishment Or Maintenance Of Microtubule Cytoskeleton Polarity Muscle Cell Development Intracellular Protein Localization Regulation Of Locomotion Import Into Nucleus Protein Import Into Nucleus MAML1-RBP-Jkappa- ICN1 Complex Apoptotic Process Involved In Embryonic Digit Morphogenesis Vasculogenesis Involved In Coronary Vascular Morphogenesis Negative Regulation Of Inner Ear Auditory Receptor Cell Differentiation
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