TENT2 and MIR9-1

Number of citations of the paper that reports this interaction (PubMedID 28431233)
0

Data Source:
BioGRID (unspecified method)

		TENT2	MIR9-1
Description		terminal nucleotidyltransferase 2	microRNA 9-1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm Nuclear RNA-directed RNA Polymerase Complex	Nucleus Cytoplasm RISC Complex Extracellular Exosome
	Molecular Function	Nucleotide Binding Protein Binding ATP Binding Transferase Activity Nucleotidyltransferase Activity Metal Ion Binding Poly(A) RNA Polymerase Activity	Single-stranded RNA Binding MRNA 3'-UTR Binding High-density Lipoprotein Particle Binding MRNA Base-pairing Post-transcriptional Repressor Activity
	Biological Process	Hematopoietic Progenitor Cell Differentiation MRNA Processing Regulation Of Gene Expression RNA 3'-end Processing MRNA 3'-end Processing Histone MRNA Catabolic Process Target-directed MiRNA Degradation Negative Regulation Of MiRNA Catabolic Process	Negative Regulation Of Cell Adhesion Negative Regulation Of Cell Population Proliferation Negative Regulation Of Gene Expression Negative Regulation Of Cell Migration Negative Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Regulatory NcRNA-mediated Gene Silencing Negative Regulation Of Osteoblast Proliferation MiRNA-mediated Post-transcriptional Gene Silencing MiRNA-mediated Gene Silencing By Inhibition Of Translation MiRNA-mediated Gene Silencing By MRNA Destabilization Negative Regulation Of Osteoblast Differentiation Negative Regulation Of Receptor Signaling Pathway Via JAK-STAT Negative Regulation Of Lipid Biosynthetic Process Negative Regulation Of Cholesterol Efflux Negative Regulation Of Extracellular Matrix Assembly Negative Regulation Of Non-canonical NF-kappaB Signal Transduction Positive Regulation Of Lymphangiogenesis Negative Regulation Of Myofibroblast Differentiation Negative Regulation Of Xenobiotic Detoxification By Transmembrane Export Across The Plasma Membrane
Pathways
Drugs
Diseases
GWAS		Leukocyte telomere length ( 32109421)
Interacting Genes		30 interacting genes: ANXA2 CADPS CALCOCO2 DTX2 KRTAP6-3 MIR10B MIR122 MIR128-1 MIR128-2 MIR138-1 MIR141 MIR145 MIR155 MIR15B MIR21 MIR222 MIR29A MIR29C MIR34B MIR363 MIR451A MIR9-1 MIR9-2 MIRLET7A1 MIRLET7A3 MIRLET7B MIRLET7C MIRLET7F2 OGT RBPMS	84 interacting genes: ADARB1 APOBEC3B C1QBP CELF1 CRTAP DARS1 DDX1 DDX21 DDX3X DHX36 EIF2AK2 EPRS1 ERAL1 ESRP1 FAM98A FAM98B FUS GRSF1 HARS2 HNRNPA0 HNRNPA1 HNRNPA2B1 HNRNPA3 HNRNPF HNRNPH1 HNRNPH2 HNRNPH3 HNRNPK HNRNPL HNRNPM HNRNPR IARS1 IGF2BP1 IGF2BP2 IGF2BP3 KARS1 KNOP1 LARP7 LARS1 LIN28A LIN28B LRPPRC MARS1 MATR3 MSI2 MYEF2 NOL6 NONO NUDT16L1 PDCD11 PLOD1 PRMT1 PTBP1 PUF60 QARS1 RARS1 RBFOX2 RBM14 RBM4 RTCA RTCB SF3B1 SF3B2 SF3B3 SF3B4 SFPQ SPOUT1 STRBP SUGP2 SYMPK SYNCRIP TAF15 TENT2 TRA2A TRA2B U2SURP UPF1 UTP20 YBX1 YBX3 ZC3H11A ZFR ZNF346 ZNF385A
Entrez ID		167153	407046
HPRD ID		15098
Ensembl ID		ENSG00000164329	ENSG00000207933
Uniprot IDs		D6RAF2 Q6PIY7
PDB IDs
Enriched GO Terms of Interacting Partners?		MiRNA-mediated Post-transcriptional Gene Silencing Regulatory NcRNA-mediated Post-transcriptional Gene Silencing Post-transcriptional Gene Silencing RISC Complex Regulatory NcRNA-mediated Gene Silencing MRNA Base-pairing Post-transcriptional Repressor Activity Post-transcriptional Regulation Of Gene Expression MRNA 3'-UTR Binding Negative Regulation Of Gene Expression MiRNA-mediated Gene Silencing By Inhibition Of Translation Negative Regulation Of Translation Extracellular Vesicle Negative Regulation Of Macromolecule Biosynthetic Process Negative Regulation Of Macromolecule Metabolic Process Negative Regulation Of Biosynthetic Process Negative Regulation Of Metabolic Process Negative Regulation Of Cell Migration Negative Regulation Of Cell Motility MiRNA-mediated Gene Silencing By MRNA Destabilization Negative Regulation Of Locomotion Regulation Of Translation Regulation Of Blood Vessel Endothelial Cell Proliferation Involved In Sprouting Angiogenesis Negative Regulation Of Protein Metabolic Process Negative Regulation Of Angiogenesis Negative Regulation Of Vasculature Development Regulation Of Angiogenesis Regulation Of Vasculature Development Regulation Of Cell Migration Regulation Of Gene Expression MRNA Destabilization RNA Destabilization Regulation Of Macromolecule Biosynthetic Process Regulation Of Cell Motility Regulation Of Locomotion Positive Regulation Of MRNA Catabolic Process Extracellular Space Positive Regulation Of MRNA Metabolic Process Regulation Of Metabolic Process Regulation Of Endothelial Cell Proliferation Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Regulation Of Macromolecule Metabolic Process Negative Regulation Of Xenobiotic Detoxification By Transmembrane Export Across The Plasma Membrane Negative Regulation Of Response To Drug Negative Regulation Of Signal Transduction Negative Regulation Of Multicellular Organismal Process Negative Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Regulation Of MRNA Stability Regulation Of Endothelial Cell Migration Negative Regulation Of Cell Communication Negative Regulation Of Signaling	RNA Binding Nucleic Acid Binding RNA Processing RNA Metabolic Process RNA Splicing Nucleic Acid Metabolic Process MRNA Processing MRNA Metabolic Process Nucleobase-containing Compound Metabolic Process MRNA Binding Regulation Of RNA Splicing Regulation Of MRNA Metabolic Process Macromolecule Metabolic Process Ribonucleoprotein Complex Nucleus Nucleoplasm MRNA Splicing, Via Spliceosome Post-transcriptional Regulation Of Gene Expression RNA Splicing, Via Transesterification Reactions Aminoacyl-tRNA Synthetase Multienzyme Complex Regulation Of MRNA Processing Regulation Of MRNA Splicing, Via Spliceosome Spliceosomal Complex MRNA 3'-UTR Binding Negative Regulation Of MRNA Metabolic Process Regulation Of Translation Catalytic Step 2 Spliceosome Negative Regulation Of RNA Catabolic Process MiRNA Binding TRNA Aminoacylation For Protein Translation Aminoacyl-tRNA Ligase Activity Regulation Of Gene Expression TRNA Aminoacylation TRNA Metabolic Process Regulation Of Macromolecule Biosynthetic Process Cytoplasmic Stress Granule Positive Regulation Of Gene Expression Regulation Of Macromolecule Metabolic Process Negative Regulation Of MRNA Catabolic Process Negative Regulation Of Translation RNA Stabilization Regulation Of Primary Metabolic Process Ligase Activity Regulation Of RNA Stability MRNA Stabilization Regulation Of Alternative MRNA Splicing, Via Spliceosome Nucleolus Positive Regulation Of Macromolecule Biosynthetic Process Negative Regulation Of Macromolecule Metabolic Process Regulation Of Metabolic Process
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