RBM46 and RBPMS2

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		RBM46	RBPMS2
Description		RNA binding motif protein 46	RNA binding protein, mRNA processing factor 2
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm Apolipoprotein B MRNA Editing Enzyme Complex	Nucleus Cytoplasm Cytosol Cytoplasmic Stress Granule
	Molecular Function	Nucleic Acid Binding RNA Binding MRNA Binding Protein Binding Enzyme-substrate Adaptor Activity	Nucleic Acid Binding RNA Binding MRNA Binding Protein Binding Identical Protein Binding Protein Homodimerization Activity
	Biological Process	Trophectodermal Cell Differentiation Male Meiotic Nuclear Division Female Meiotic Nuclear Division Spermatogenesis Cell Differentiation MRNA Stabilization Oogenesis Spermatid Differentiation Meiotic Cell Cycle Cell Cycle Switching, Mitotic To Meiotic Cell Cycle Negative Regulation Of MRNA Catabolic Process	Regulation Of Alternative MRNA Splicing, Via Spliceosome Negative Regulation Of BMP Signaling Pathway Embryonic Digestive Tract Morphogenesis Positive Regulation Of Smooth Muscle Cell Proliferation Negative Regulation Of Smooth Muscle Cell Differentiation
Pathways
Drugs
Diseases
GWAS		Epstein-Barr virus copy number in lymphoblastoid cell lines ( 28654678)	Coronary artery disease ( 29212778) Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098) Neuroticism ( 29255261) Platelet count ( 32888494) PR interval ( 32439900)
Interacting Genes		4 interacting genes: FOXH1 GORASP2 RBPMS RBPMS2	68 interacting genes: ACTMAP AOC1 ARID5A BHLHE40 BOLL C10orf55 CAMK2A CBX2 CELF4 DND1 ESRP1 FAM168A FOXD4L1 FOXD4L3 FOXH1 FUBP3 HNRNPC HNRNPK HNRNPU IFIT2 KLF1 KLHDC7B KRTAP11-1 KRTAP19-5 KRTAP19-6 KRTAP19-7 KRTAP6-1 KRTAP6-2 KRTAP8-1 LASP1 MAGED1 MKRN3 MSX2 MYPOP PATZ1 PCBP1 PPP1R37 PRR20A PRR20B PRR20C PRR20D PRR20E PTBP2 RALY RBFOX1 RBFOX2 RBM3 RBM41 RBM42 RBM46 RBPMS RHOXF2 SEMA3B SNRPA SPMIP9 STRBP TENT5B TIAL1 UFSP1 UNC119 USP54 VHL VPS37C ZBTB32 ZC3H10 ZMAT5 ZNF34 ZNF385C
Entrez ID		166863	348093
HPRD ID		14517	18601
Ensembl ID		ENSG00000151962	ENSG00000166831
Uniprot IDs		Q8TBY0	Q6ZRY4
PDB IDs			2M9K
Enriched GO Terms of Interacting Partners?		Regulation Of MRNA Splicing, Via Spliceosome Cytoplasmic Stress Granule Regulation Of Alternative MRNA Splicing, Via Spliceosome Regulation Of MRNA Processing Activin Responsive Factor Complex Embryonic Heart Tube Anterior/posterior Pattern Specification Regulation Of RNA Splicing MRNA CDS Binding Axial Mesoderm Development MRNA Binding Nodal Signaling Pathway Cardiac Right Ventricle Morphogenesis Determination Of Left/right Asymmetry In Lateral Mesoderm Ventricular Trabecula Myocardium Morphogenesis Co-SMAD Binding Hepatocyte Differentiation Heart Field Specification Secondary Heart Field Specification Regulation Of MRNA Metabolic Process Pre-mRNA Intronic Binding Specification Of Animal Organ Identity Embryonic Morphogenesis Negative Regulation Of Androgen Receptor Signaling Pathway Pre-mRNA Binding Embryonic Digestive Tract Morphogenesis Heart Trabecula Morphogenesis Negative Regulation Of Smooth Muscle Cell Differentiation Nuclear Androgen Receptor Binding Aorta Morphogenesis R-SMAD Binding SMAD Protein Signal Transduction Nucleic Acid Binding BHLH Transcription Factor Binding Activin Receptor Signaling Pathway Cardiac Ventricle Morphogenesis Regulation Of Androgen Receptor Signaling Pathway	Nucleic Acid Binding Regulation Of MRNA Metabolic Process Negative Regulation Of MRNA Metabolic Process RNA Binding Regulation Of RNA Splicing MRNA Binding RNA Splicing MRNA Processing Regulation Of MRNA Splicing, Via Spliceosome Spliceosomal Complex Negative Regulation Of RNA Metabolic Process Regulation Of MRNA Processing Regulation Of RNA Metabolic Process Regulation Of Nucleobase-containing Compound Metabolic Process Negative Regulation Of Nucleobase-containing Compound Metabolic Process MRNA Stabilization MRNA Metabolic Process Negative Regulation Of MRNA Catabolic Process RNA Stabilization RNA Processing MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions Regulation Of Primary Metabolic Process Negative Regulation Of RNA Catabolic Process Intermediate Filament Negative Regulation Of RNA Splicing Regulation Of Gene Expression Regulation Of Alternative MRNA Splicing, Via Spliceosome Regulation Of MRNA Stability Regulation Of Macromolecule Biosynthetic Process MRNA 3'-UTR Binding Protein Binding Ribonucleoprotein Complex Regulation Of RNA Stability Regulation Of Macromolecule Metabolic Process Pre-mRNA Binding Negative Regulation Of Macromolecule Metabolic Process Nucleus Negative Regulation Of MRNA Splicing, Via Spliceosome Post-transcriptional Regulation Of Gene Expression DNA Binding Regulation Of MiRNA-mediated Gene Silencing Regulation Of Post-transcriptional Gene Silencing Negative Regulation Of Macromolecule Biosynthetic Process Negative Regulation Of Metabolic Process Regulation Of Metabolic Process RNA Metabolic Process Negative Regulation Of Biosynthetic Process Regulation Of Transcription By RNA Polymerase II Negative Regulation Of Transcription By RNA Polymerase II
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