FGF12 and RP9

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		FGF12	RP9
Description		fibroblast growth factor 12	RP9 pre-mRNA splicing factor
Image			No pdb structure
GO Annotations	Cellular Component	Extracellular Space Nucleus Cytoplasm Synapse	Nucleus Signal Recognition Particle Receptor Complex
	Molecular Function	Fibroblast Growth Factor Receptor Binding Protein Binding Growth Factor Activity Heparin Binding Sodium Channel Regulator Activity Transmembrane Transporter Binding	RNA Binding Protein Binding Zinc Ion Binding Metal Ion Binding
	Biological Process	Signal Transduction JNK Cascade Cell-cell Signaling Chemical Synaptic Transmission Nervous System Development Heart Development Adult Locomotory Behavior Fibroblast Growth Factor Receptor Signaling Pathway Positive Regulation Of Sodium Ion Transport Neurogenesis Neuromuscular Process Cardiac Muscle Cell Action Potential Involved In Contraction Regulation Of Neuronal Action Potential Regulation Of Sodium Ion Transmembrane Transport Regulation Of Voltage-gated Sodium Channel Activity	RNA Splicing Cognition
Pathways		Phase 0 - rapid depolarisation
Drugs
Diseases			Retinitis pigmentosa (RP)
GWAS		Age-related cognitive decline (memory) (slope of z-scores) ( 30954325) Bipolar disorder ( 31043756) Fasting glucose ( 34059833) Gut microbiota relative abundance (Ruminococcus belonging to family Erysipelotrichaceae) ( 33208821) HDL cholesterol levels in HIV infection ( 33109212) Height ( 32902719) Hip circumference adjusted for BMI ( 28552196) Idiopathic dilated cardiomyopathy ( 29495422) Ileal carcinoids ( 21139019) Major depressive disorder ( 23377640) Metabolite levels ( 19043545) Orofacial cleft x maternal periconceptional smoking interaction (1df) ( 33937227) Post bronchodilator FEV1/FVC ratio ( 26634245) PR interval ( 32439900) Serum metabolite concentrations in chronic kidney disease ( 29545352) Severe influenza A (H1N1) infection ( 26379185) Sleep quality ( 23728906)
Interacting Genes		25 interacting genes: APP COIL CT45A1 DACH1 DCTD DPPA2 GRIP1 IKZF1 LZTS2 MAPK13 MAPK8IP2 NEDD4 NEDD4L PJA1 RBAK RNF151 RP9 SMURF1 SRPK1 SRPK2 STAC3 THAP1 YWHAE ZNF460 ZNF79	10 interacting genes: AP1M1 APP BYSL C1orf35 CIRSR FGF12 NKAPD1 SDCBP SREK1IP1 U2AF1
Entrez ID		2257	6100
HPRD ID		03303	08457
Ensembl ID		ENSG00000114279	ENSG00000164610
Uniprot IDs		A0A804HIN2 C9JEN8 P61328	A0A090N8Z0 Q8TA86
PDB IDs		1Q1U 4JQ0
Enriched GO Terms of Interacting Partners?		Receptor Catabolic Process Regulation Of Monoatomic Cation Transmembrane Transport Transmembrane Transporter Binding Sodium Channel Inhibitor Activity Phosphoserine Residue Binding Receptor Metabolic Process Negative Regulation Of Potassium Ion Export Across Plasma Membrane Regulation Of Monoatomic Ion Transmembrane Transport Potassium Channel Inhibitor Activity Regulation Of Potassium Ion Transmembrane Transport Regulation Of Potassium Ion Export Across Plasma Membrane Receptor Internalization Negative Regulation Of Sodium Ion Transport Negative Regulation Of Cation Transmembrane Transport Negative Regulation Of Monoatomic Ion Transmembrane Transport Regulation Of Potassium Ion Transport Negative Regulation Of Protein Localization Regulation Of Monoatomic Ion Transport Zinc Ion Binding Positive Regulation Of Dendrite Extension Regulation Of Membrane Potential Mating Behavior Negative Regulation Of Potassium Ion Transmembrane Transport Negative Regulation Of Monoatomic Ion Transport Low-density Lipoprotein Particle Receptor Binding Negative Regulation Of Transmembrane Transport Positive Regulation Of Receptor Internalization Protein Polyubiquitination Negative Regulation Of Potassium Ion Transport Positive Regulation Of Viral Genome Replication Amyloid-beta Complex Growth Cone Lamellipodium Regulation Of Response To Calcium Ion Amylin Binding Positive Regulation Of Toll Signaling Pathway Protein Binding Positive Regulation Of Transport Reproductive Behavior Negative Regulation Of Fibroblast Proliferation Neuromuscular Junction Development Formation Of Structure Involved In A Symbiotic Process Regulation Of Membrane Repolarization Engulfment Of Target By Autophagosome Primary Ureteric Bud Growth Regulation Of Toll-like Receptor Signaling Pathway	Acetylcholine Receptor Activator Activity Amyloid-beta Complex PTB Domain Binding Growth Cone Lamellipodium Adult Locomotory Behavior Collateral Sprouting In Absence Of Injury Regulation Of Protein Import Response To Norepinephrine Regulation Of Endoplasmic Reticulum Stress-induced Neuron Intrinsic Apoptotic Signaling Pathway Trans-synaptic Signaling Chemical Synaptic Transmission Regulation Of Response To Calcium Ion Trans-Golgi Network Membrane Amylin Binding Positive Regulation Of JNK Cascade Endosome To Plasma Membrane Transport Vesicle Positive Regulation Of Toll Signaling Pathway Positive Regulation Of Endothelin Production Growth Cone Filopodium Cellular Response To Norepinephrine Stimulus Lipoprotein Particle Synaptic Signaling Regulation Of Receptor Internalization Phospholipase D-activating G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Protein Import Frizzled Binding Astrocyte Activation Involved In Immune Response Regulation Of Nervous System Process Microglia Development Positive Regulation Of G Protein-coupled Receptor Internalization Synapse Low-density Lipoprotein Particle Mediated Signaling RNA Processing Regulation Of Voltage-gated Sodium Channel Activity Interleukin-5 Receptor Binding Interleukin-5 Receptor Complex Positive Regulation Of Extracellular Exosome Assembly Syndecan Binding MRNA Processing RNA Splicing Intermediate-density Lipoprotein Particle Axon Midline Choice Point Recognition Positive Regulation Of Amyloid Fibril Formation Regulation Of Receptor-mediated Endocytosis Growth Factor Receptor Binding Main Axon Protein Insertion Into Mitochondrial Inner Membrane From Matrix Regulation Of Neuronal Action Potential
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