FGF12 and RNF151

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		FGF12	RNF151
Description		fibroblast growth factor 12	ring finger protein 151
Image			No pdb structure
GO Annotations	Cellular Component	Extracellular Space Nucleus Cytoplasm Synapse	Nucleus Cytoplasm
	Molecular Function	Fibroblast Growth Factor Receptor Binding Protein Binding Growth Factor Activity Heparin Binding Sodium Channel Regulator Activity Transmembrane Transporter Binding	Protein Binding Zinc Ion Binding Enzyme Binding Identical Protein Binding Metal Ion Binding
	Biological Process	Signal Transduction JNK Cascade Cell-cell Signaling Chemical Synaptic Transmission Nervous System Development Heart Development Adult Locomotory Behavior Fibroblast Growth Factor Receptor Signaling Pathway Positive Regulation Of Sodium Ion Transport Neurogenesis Neuromuscular Process Cardiac Muscle Cell Action Potential Involved In Contraction Regulation Of Neuronal Action Potential Regulation Of Sodium Ion Transmembrane Transport Regulation Of Voltage-gated Sodium Channel Activity	Spermatogenesis Cell Differentiation
Pathways		Phase 0 - rapid depolarisation
Drugs
Diseases
GWAS		Age-related cognitive decline (memory) (slope of z-scores) ( 30954325) Bipolar disorder ( 31043756) Fasting glucose ( 34059833) Gut microbiota relative abundance (Ruminococcus belonging to family Erysipelotrichaceae) ( 33208821) HDL cholesterol levels in HIV infection ( 33109212) Height ( 32902719) Hip circumference adjusted for BMI ( 28552196) Idiopathic dilated cardiomyopathy ( 29495422) Ileal carcinoids ( 21139019) Major depressive disorder ( 23377640) Metabolite levels ( 19043545) Orofacial cleft x maternal periconceptional smoking interaction (1df) ( 33937227) Post bronchodilator FEV1/FVC ratio ( 26634245) PR interval ( 32439900) Serum metabolite concentrations in chronic kidney disease ( 29545352) Severe influenza A (H1N1) infection ( 26379185) Sleep quality ( 23728906)	Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098)
Interacting Genes		25 interacting genes: APP COIL CT45A1 DACH1 DCTD DPPA2 GRIP1 IKZF1 LZTS2 MAPK13 MAPK8IP2 NEDD4 NEDD4L PJA1 RBAK RNF151 RP9 SMURF1 SRPK1 SRPK2 STAC3 THAP1 YWHAE ZNF460 ZNF79	18 interacting genes: ABT1 APP C1orf35 CT45A1 DVL3 FAM133A FAM9A FGF12 NKAPD1 PIBF1 PRPF3 SCARA5 SREK1IP1 TSPYL2 UBC UBE2D2 UBE2I ZC4H2
Entrez ID		2257	146310
HPRD ID		03303	19116
Ensembl ID		ENSG00000114279	ENSG00000179580
Uniprot IDs		A0A804HIN2 C9JEN8 P61328	H3BNJ8 Q2KHN1
PDB IDs		1Q1U 4JQ0
Enriched GO Terms of Interacting Partners?		Receptor Catabolic Process Regulation Of Monoatomic Cation Transmembrane Transport Transmembrane Transporter Binding Sodium Channel Inhibitor Activity Phosphoserine Residue Binding Receptor Metabolic Process Negative Regulation Of Potassium Ion Export Across Plasma Membrane Regulation Of Monoatomic Ion Transmembrane Transport Potassium Channel Inhibitor Activity Regulation Of Potassium Ion Transmembrane Transport Regulation Of Potassium Ion Export Across Plasma Membrane Receptor Internalization Negative Regulation Of Sodium Ion Transport Negative Regulation Of Cation Transmembrane Transport Negative Regulation Of Monoatomic Ion Transmembrane Transport Regulation Of Potassium Ion Transport Negative Regulation Of Protein Localization Regulation Of Monoatomic Ion Transport Zinc Ion Binding Positive Regulation Of Dendrite Extension Regulation Of Membrane Potential Mating Behavior Negative Regulation Of Potassium Ion Transmembrane Transport Negative Regulation Of Monoatomic Ion Transport Low-density Lipoprotein Particle Receptor Binding Negative Regulation Of Transmembrane Transport Positive Regulation Of Receptor Internalization Protein Polyubiquitination Negative Regulation Of Potassium Ion Transport Positive Regulation Of Viral Genome Replication Amyloid-beta Complex Growth Cone Lamellipodium Regulation Of Response To Calcium Ion Amylin Binding Positive Regulation Of Toll Signaling Pathway Protein Binding Positive Regulation Of Transport Reproductive Behavior Negative Regulation Of Fibroblast Proliferation Neuromuscular Junction Development Formation Of Structure Involved In A Symbiotic Process Regulation Of Membrane Repolarization Engulfment Of Target By Autophagosome Primary Ureteric Bud Growth Regulation Of Toll-like Receptor Signaling Pathway
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