DNAAF4 and SPDL1

Number of citations of the paper that reports this interaction (PubMedID 26871637)
43

Data Source:
BioGRID (two hybrid)

		DNAAF4	SPDL1
Description		dynein axonemal assembly factor 4	spindle apparatus coiled-coil protein 1
Image		No pdb structure
GO Annotations	Cellular Component	Extracellular Region Nucleus Cytoplasm Cytosol Plasma Membrane Cell Projection Neuron Projection Dynein Axonemal Particle	Chromosome, Centromeric Region Kinetochore Spindle Pole Outer Kinetochore Nucleus Chromosome Cytoplasm Centrosome Cytosol Cytoskeleton
	Molecular Function	Protein Binding Nuclear Estrogen Receptor Binding	Protein Binding Enzyme Binding Kinetochore Binding
	Biological Process	Neuron Migration Cilium Movement Epithelial Cilium Movement Involved In Extracellular Fluid Movement Determination Of Left/right Symmetry Nervous System Development Heart Development Learning Or Memory Regulation Of Intracellular Estrogen Receptor Signaling Pathway Outer Dynein Arm Assembly Inner Dynein Arm Assembly Establishment Of Localization In Cell Regulation Of Proteasomal Protein Catabolic Process	Establishment Of Mitotic Spindle Orientation Mitotic Metaphase Chromosome Alignment Mitotic Spindle Assembly Checkpoint Signaling Cell Migration Protein Localization To Kinetochore Cell Division
Pathways			Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal Separation of Sister Chromatids Resolution of Sister Chromatid Cohesion RHO GTPases Activate Formins Mitotic Prometaphase EML4 and NUDC in mitotic spindle formation
Drugs
Diseases
GWAS			Bipolar disorder x sex interaction ( 34099189)
Interacting Genes		10 interacting genes: BANF2 CRACR2B EXOC5 HSPA1A KDM1A KRT13 MCC SPDL1 STUB1 TRIM23	10 interacting genes: CA8 CEP126 DNAAF4 GPS2 ITSN1 PPP1R18 RTP5 TRAF4 USP15 USP45
Entrez ID		161582	54908
HPRD ID		10568	08623
Ensembl ID		ENSG00000256061	ENSG00000040275
Uniprot IDs		A0A0S2Z5Z4 Q8WXU2	Q96EA4
PDB IDs			8ARF
Enriched GO Terms of Interacting Partners?
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