DAP and TRIO

  • Data Source: HiPPIP (Novel)

DAP

TRIO

Name death associated protein trio Rho guanine nucleotide exchange factor
Structure No pdb structure PDB 1NTY
GO Annotations Cellular Component None
Molecular Function
Biological Process
Pathways None
GWAS
  • Basophil percentage of white cells ( 32888494 )
  • Cervical high-risk human papilloma virus infection (persistent) ( 33225922 )
  • Chronic inflammatory diseases (ankylosing spondylitis, Crohn's disease, psoriasis, primary sclerosing cholangitis, ulcerative colitis) (pleiotropy) ( 26974007 )
  • Crohn's disease ( 28067908 )
  • Gut microbiota (functional units) ( 27694959 )
  • Height ( 28270201 )
  • Inflammatory bowel disease ( 23128233 28067908 )
  • Lymphocyte percentage of white cells ( 32888494 )
  • Metabolite levels ( 23823483 )
  • Metabolite levels (Pyroglutamine) ( 23934736 )
  • Pulse pressure ( 27841878 )
  • Sum eosinophil basophil counts ( 27863252 )
  • Systolic blood pressure ( 27841878 )
  • Ulcerative colitis ( 21297633 )
  • Adverse response to chemotherapy in breast cancer (alopecia) (paclitaxel) ( 24025145 )
  • Antidepressant treatment resistance (number of drugs prescribed) ( 30700811 )
  • Asthma ( 31959851 )
  • Asthma (childhood onset) ( 31036433 )
  • Electroencephalogram traits ( 25387704 )
  • High density lipoprotein cholesterol levels ( 30498476 )
  • Intake of total sugars ( 31005972 )
  • Major depressive disorder ( 27777418 )
  • Paclitaxel-induced neuropathy ( 23776197 )
  • Physiological dysregulation (Mahalanobis distance) ( 32235003 )
  • Response to selenium supplementation (change in plasma selenium concentration) ( 33382417 )
  • Waist circumference ( 28552196 )
Novel Interactors 3 novel interactors: DNAH5 RASGRP1 TRIO 5 novel interactors: DAP DNAH5 MARCHF6 NIPBL PRMT7
Interacting Genes 1 interacting genes: SETDB1 13 interacting genes: BLMH CDC42 CDC5L DISC1 DSCR9 EXOC1 FLNA ITSN2 LIMS1 PTK2 PTPRF RAC1 RHOA
Entrez ID 1611 7204
HPRD ID 02977 03537
Ensembl ID ENSG00000112977 ENSG00000038382
Uniprot IDs B4DQ75 P51397 O75962
PDB IDs Not available 1NTY 2NZ8 6D8Z 7SJ4
GO Terms Enriched among Interactors None