AARS and EEF1B2

Number of citations of the paper that reports this interaction (PMID 11829477)
11

Data Source:
HPRD (two hybrid)

		AARS	EEF1B2
Gene Name		alanyl-tRNA synthetase	eukaryotic translation elongation factor 1 beta 2
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Cytoplasm Cytosol Membrane Extracellular Vesicular Exosome	Cytosol Eukaryotic Translation Elongation Factor 1 Complex
	Molecular Function	TRNA Binding Aminoacyl-tRNA Editing Activity Alanine-tRNA Ligase Activity ATP Binding Zinc Ion Binding Amino Acid Binding	Translation Elongation Factor Activity Protein Binding
	Biological Process	Hair Follicle Development TRNA Modification TRNA Aminoacylation For Protein Translation Alanyl-tRNA Aminoacylation Regulation Of Translational Fidelity Protein Folding TRNA Processing Gene Expression Cerebellar Purkinje Cell Layer Development Endoplasmic Reticulum Unfolded Protein Response Response To Amino Acid Negative Regulation Of Neuron Apoptotic Process Neuromuscular Process Controlling Balance	Translation Translational Elongation Gene Expression Cellular Protein Metabolic Process
Pathways		Cytosolic tRNA aminoacylation tRNA Aminoacylation	Translation Eukaryotic Translation Elongation
Drugs		L-Alanine
Diseases
GWAS
Protein-Protein Interactions		1 interactors: EEF1B2	10 interactors: AARS APP CSNK2A1 CSNK2A2 DRD3 EEF1G HARS TIMP1 ULK2 VHL
Entrez ID		16	1933
HPRD ID		03042	02804
Ensembl ID		ENSG00000090861	ENSG00000114942
Uniprot IDs		P49588	P24534
PDB IDs			1B64
Enriched GO Terms of Interacting Partners?			Negative Regulation Of Proteolysis Negative Regulation Of Protein Processing Negative Regulation Of Protein Catabolic Process Regulation Of Protein Processing Regulation Of Mitotic Nuclear Division Regulation Of Mitotic Cell Cycle Neuromuscular Process Response To External Stimulus Regulation Of Cell Cycle Process Cell Morphogenesis Cellular Protein Metabolic Process Axonogenesis Axon Development Cell Morphogenesis Involved In Neuron Differentiation Negative Regulation Of Cellular Metabolic Process Regulation Of Growth Regulation Of Mitotic Cell Cycle Phase Transition Neuron Projection Morphogenesis Regulation Of Cell Cycle Phase Transition Regulation Of Proteolysis Nervous System Development Mitotic Spindle Checkpoint Negative Regulation Of Chromosome Segregation Regulation Of Cell Division Negative Regulation Of Endopeptidase Activity Cell Morphogenesis Involved In Differentiation Negative Regulation Of Peptidase Activity Regulation Of Mitotic Sister Chromatid Separation Negative Regulation Of Mitotic Nuclear Division Spindle Checkpoint Negative Regulation Of Neurogenesis Regulation Of Developmental Growth Negative Regulation Of Catalytic Activity Regulation Of Mitotic Metaphase/anaphase Transition Generation Of Neurons Developmental Process Negative Regulation Of Cellular Protein Metabolic Process Protein Metabolic Process Neuron Projection Development Cell Projection Morphogenesis Negative Regulation Of Cell Development Visual Learning Cell Part Morphogenesis Neurogenesis Negative Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Negative Regulation Of Protein Metabolic Process Visual Behavior Negative Regulation Of Proteasomal Protein Catabolic Process Negative Regulation Of Apoptotic Process Platelet Degranulation
Tagcloud ?		acylating aminoacyl aminoars aminoarss bodies canonical dorsal drg functions ganglia glutaminyl horn injured kars lysyl nerve pharmaceutical possibility powerful primers qars root satellite sensory spinal synthetase synthetases trna typical	aberration aberrations amplicons amplifications cna cnas concordance concordant copy featured gains gistic grouped hnf4a instable microsatellite msi mss oncogenes petacc ptk6 q q23 reinforce smad4 suppressors unlinked wnk1 wwox
Tagcloud (Difference) ?		acylating aminoacyl aminoars aminoarss bodies canonical dorsal drg functions ganglia glutaminyl horn injured kars lysyl nerve pharmaceutical possibility powerful primers qars root satellite sensory spinal synthetase synthetases trna typical	aberration aberrations amplicons amplifications cna cnas concordance concordant copy featured gains gistic grouped hnf4a instable microsatellite msi mss oncogenes petacc ptk6 q q23 reinforce smad4 suppressors unlinked wnk1 wwox
Tagcloud (Intersection) ?