RDH10 and RMDN2

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		RDH10	RMDN2
Description		retinol dehydrogenase 10	regulator of microtubule dynamics 2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm Endoplasmic Reticulum Endoplasmic Reticulum Membrane Lipid Droplet Membrane	Spindle Pole Cytoplasm Mitochondrion Golgi Apparatus Spindle Cytosol Cytoskeleton Microtubule Spindle Microtubule Membrane Mitotic Spindle Mitotic Spindle Pole
	Molecular Function	All-trans-retinol Dehydrogenase (NAD+) Activity Protein Binding Oxidoreductase Activity Oxidoreductase Activity, Acting On The CH-OH Group Of Donors, NAD Or NADP As Acceptor All-trans-retinol Dehydrogenase (NADP+) Activity	Protein Binding Microtubule Binding
	Biological Process	Retinoid Metabolic Process Metanephros Development In Utero Embryonic Development Retinoic Acid Biosynthetic Process Lipid Metabolic Process Visual Perception Gonad Development Animal Organ Morphogenesis Regulation Of Hormone Levels Neural Crest Cell Development Embryonic Camera-type Eye Development Embryonic Forelimb Morphogenesis Retinol Metabolic Process Retinal Metabolic Process Ear Development Nose Development Embryonic Organ Development Embryonic Viscerocranium Morphogenesis Primary Lung Bud Formation Bud Elongation Involved In Lung Branching Positive Regulation Of Retinoic Acid Biosynthetic Process
Pathways		The canonical retinoid cycle in rods (twilight vision) RA biosynthesis pathway
Drugs
Diseases
GWAS		Anthracycline-induced cardiotoxicity in early breast cancer ( 32378780) Ceramide levels (C24:0) ( 32489964) Crohn's disease ( 22412388) Refractive error ( 32231278) Systolic blood pressure ( 30578418)	Childhood asthma exacerbations in long-acting beta2-agonist treatment ( 33706416) Cutaneous malignant melanoma ( 26237428) Eosinophil count ( 32888494) Melanoma ( 28212542)
Interacting Genes		4 interacting genes: ACSF2 DDA1 GAD2 RMDN2	14 interacting genes: AGTRAP CMTM5 DIABLO HSD17B11 LMNA RDH10 RTN3 SAR1A STX1A THAP4 TNFRSF10D VAPA VAPB VEZT
Entrez ID		157506	151393
HPRD ID		07605	08741
Ensembl ID		ENSG00000121039	ENSG00000115841
Uniprot IDs		Q8IZV5	A0A0C4DFM4 Q96LZ7
PDB IDs
Enriched GO Terms of Interacting Partners?		Gamma-aminobutyric Acid Biosynthetic Process L-glutamate Catabolic Process Gamma-aminobutyric Acid Metabolic Process Carbon-carbon Lyase Activity Succinate Metabolic Process Gamma-aminobutyrate Shunt Glutamate Decarboxylase Activity Clathrin-sculpted Gamma-aminobutyric Acid Transport Vesicle Membrane Medium-chain Fatty Acid-CoA Ligase Activity Long-chain Fatty Acid-CoA Ligase Activity Dicarboxylic Acid Catabolic Process Monocarboxylic Acid Metabolic Process Carboxy-lyase Activity	FFAT Motif Binding Endoplasmic Reticulum Exit Site Membrane Organization COPII-coated Vesicle Budding Endoplasmic Reticulum-plasma Membrane Tethering Endoplasmic Reticulum Localization Endoplasmic Reticulum Organization Organelle Localization By Membrane Tethering Host-mediated Activation Of Viral Genome Replication Host-mediated Perturbation Of Viral Genome Replication Membrane Docking Host-mediated Suppression Of Viral Genome Replication Endoplasmic Reticulum Membrane Organization Endoplasmic Reticulum Vesicle Organization Endoplasmic Reticulum Membrane Endoplasmic Reticulum To Golgi Vesicle-mediated Transport Myosin Binding Viral Release From Host Cell Vesicle Budding From Membrane Protein-membrane Adaptor Activity Organelle Localization Host-mediated Activation Of Viral Process Myosin Head/neck Binding Peroxynitrite Isomerase Activity Primary Lung Bud Formation Positive Regulation Of Retinoic Acid Biosynthetic Process Oxidoreductase Activity, Acting On The CH-OH Group Of Donors, NAD Or NADP As Acceptor Nuclear Membrane Cholesterol Transport Golgi Vesicle Transport DNA Double-strand Break Attachment To Nuclear Envelope Structural Constituent Of Nuclear Lamina Negative Regulation By Virus Of Viral Protein Levels In Host Cell Amino Acid Sensor Activity Vesicle-mediated Transport Host-mediated Perturbation Of Viral Process Intracellular Transport Sterol Transport Positive Regulation Of Norepinephrine Secretion Synaptobrevin 2-SNAP-25-syntaxin-1a-complexin II Complex Nitrate Metabolic Process Steroid Dehydrogenase Activity Lipid Droplet Establishment Or Maintenance Of Microtubule Cytoskeleton Polarity Synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I Complex Synaptobrevin 2-SNAP-25-syntaxin-1a Complex Angiotensin Type II Receptor Activity Regulation Of Isoprenoid Metabolic Process Host-mediated Perturbation Of Symbiont Process
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?