RMDN2 and THAP4

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		RMDN2	THAP4
Description		regulator of microtubule dynamics 2	THAP domain containing 4
Image		No pdb structure
GO Annotations	Cellular Component	Spindle Pole Cytoplasm Mitochondrion Golgi Apparatus Spindle Cytosol Cytoskeleton Microtubule Spindle Microtubule Membrane Mitotic Spindle Mitotic Spindle Pole	Nucleus Nucleoplasm Cytoplasm Cytosol
	Molecular Function	Protein Binding Microtubule Binding	DNA Binding Protein Binding Zinc Ion Binding Isomerase Activity Heme Binding Identical Protein Binding Metal Ion Binding Peroxynitrite Isomerase Activity Nitric Oxide Binding
	Biological Process		Tyrosine Metabolic Process Nitrate Metabolic Process
Pathways
Drugs
Diseases
GWAS		Childhood asthma exacerbations in long-acting beta2-agonist treatment ( 33706416) Cutaneous malignant melanoma ( 26237428) Eosinophil count ( 32888494) Melanoma ( 28212542)	Brain structure ( 20171287) Femur bone mineral density x serum urate levels interaction ( 34046847) Hip circumference adjusted for BMI ( 34021172) Platelet count ( 32888494) Prostate cancer ( 23535732) Thyroid stimulating hormone levels ( 32769997)
Interacting Genes		14 interacting genes: AGTRAP CMTM5 DIABLO HSD17B11 LMNA RDH10 RTN3 SAR1A STX1A THAP4 TNFRSF10D VAPA VAPB VEZT	43 interacting genes: AGTRAP AIG1 AMD1 ANKRD46 APP BSND CACNG1 CD81 CLCA4 CMTM5 CMTM7 COL4A5 CPNE2 CTSA CYP4F2 DGAT2L6 FKBP7 GIMAP1 GPR37L1 IGFBP5 LAT LCOR LPAR3 MAL2 MAPK6 MOB4 MS4A1 NDRG4 PLP2 RMDN2 RTP2 SCAMP1 SLC30A8 SYP TMEM107 TMEM60 TMEM86A TMEM86B TNFRSF10D TPD52 TRIM54 TTPA YIPF6
Entrez ID		151393	51078
HPRD ID		08741	11630
Ensembl ID		ENSG00000115841	ENSG00000176946
Uniprot IDs		A0A0C4DFM4 Q96LZ7	Q8WY91
PDB IDs			3IA8
Enriched GO Terms of Interacting Partners?		FFAT Motif Binding Endoplasmic Reticulum Exit Site Membrane Organization COPII-coated Vesicle Budding Endoplasmic Reticulum-plasma Membrane Tethering Endoplasmic Reticulum Localization Endoplasmic Reticulum Organization Organelle Localization By Membrane Tethering Host-mediated Activation Of Viral Genome Replication Host-mediated Perturbation Of Viral Genome Replication Membrane Docking Host-mediated Suppression Of Viral Genome Replication Endoplasmic Reticulum Membrane Organization Endoplasmic Reticulum Vesicle Organization Endoplasmic Reticulum Membrane Endoplasmic Reticulum To Golgi Vesicle-mediated Transport Myosin Binding Viral Release From Host Cell Vesicle Budding From Membrane Protein-membrane Adaptor Activity Organelle Localization Host-mediated Activation Of Viral Process Myosin Head/neck Binding Peroxynitrite Isomerase Activity Primary Lung Bud Formation Positive Regulation Of Retinoic Acid Biosynthetic Process Oxidoreductase Activity, Acting On The CH-OH Group Of Donors, NAD Or NADP As Acceptor Nuclear Membrane Cholesterol Transport Golgi Vesicle Transport DNA Double-strand Break Attachment To Nuclear Envelope Structural Constituent Of Nuclear Lamina Negative Regulation By Virus Of Viral Protein Levels In Host Cell Amino Acid Sensor Activity Vesicle-mediated Transport Host-mediated Perturbation Of Viral Process Intracellular Transport Sterol Transport Positive Regulation Of Norepinephrine Secretion Synaptobrevin 2-SNAP-25-syntaxin-1a-complexin II Complex Nitrate Metabolic Process Steroid Dehydrogenase Activity Lipid Droplet Establishment Or Maintenance Of Microtubule Cytoskeleton Polarity Synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I Complex Synaptobrevin 2-SNAP-25-syntaxin-1a Complex Angiotensin Type II Receptor Activity Regulation Of Isoprenoid Metabolic Process Host-mediated Perturbation Of Symbiont Process	Membrane Alkenylglycerophosphocholine Hydrolase Activity Vitamin E Metabolic Process
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