VPS37D and ARMC7

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		VPS37D	ARMC7
Description		VPS37D subunit of ESCRT-I	armadillo repeat containing 7
Image		No pdb structure
GO Annotations	Cellular Component	ESCRT I Complex Endosome Endosome Membrane Membrane Late Endosome Membrane Extracellular Exosome	Spliceosomal Complex
	Molecular Function	Protein Binding	Protein Binding
	Biological Process	Protein Targeting To Membrane Protein Targeting To Vacuole Protein Transport Macroautophagy Multivesicular Body Assembly Viral Budding Via Host ESCRT Complex Ubiquitin-dependent Protein Catabolic Process Via The Multivesicular Body Sorting Pathway Protein Transport To Vacuole Involved In Ubiquitin-dependent Protein Catabolic Process Via The Multivesicular Body Sorting Pathway Membrane Fission	MRNA Processing RNA Splicing
Pathways		Budding and maturation of HIV virion Membrane binding and targetting of GAG proteins Endosomal Sorting Complex Required For Transport (ESCRT) HCMV Late Events Late endosomal microautophagy
Drugs
Diseases
GWAS		Coffee consumption (cups per day) ( 25288136) Gamma glutamyl transferase levels ( 29403010) Hypertriglyceridemia ( 23505323) Malaria ( 31844061) Serum albumin levels ( 29403010) Serum uric acid levels ( 29403010)	Bipolar disorder ( 31043756)
Interacting Genes		5 interacting genes: ARMC7 CEP55 HGS SNCA TSG101	71 interacting genes: ABI2 ABI3 AKAP19 APP CBY2 CCDC28B CCDC33 CDC42EP1 CFAP68 CHCHD3 CPSF6 CPSF7 DISC1 DPEP2NB DTX2 EFHC2 ESS2 GATA1 GIGYF1 HGS HOXA1 IKZF1 IKZF3 INCA1 KCTD13 KRT31 KRT34 KRT39 KRT40 KRT75 KRTAP13-1 KRTAP19-7 KRTAP6-3 LZTS2 MDFI NME4 PAK5 PIMREG PLEKHG4 PNMA6A REL RRP7A RUNDC3A SAXO1 SAXO5 SEPTIN14 SHISA6 SLAIN1 SPATC1L SPG21 SYF2 TASOR2 TCF4 TFIP11 TNFAIP1 TNNI1 TRIB3 TRIM27 TRIM42 TRIM54 USP54 VIM VPS37D YPEL3 ZBTB8A ZC2HC1C ZMAT5 ZNF140 ZNF426 ZNF669 ZNF764
Entrez ID		155382	79637
HPRD ID		19106	08649
Ensembl ID		ENSG00000176428	ENSG00000125449
Uniprot IDs		Q86XT2	J3KST7 J3KTE5 Q9H6L4
PDB IDs			7DVQ
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Exocytosis Negative Regulation Of Platelet-derived Growth Factor Receptor Signaling Pathway Membrane Organization Regulation Of Exocytosis Protein Transport To Vacuole Involved In Ubiquitin-dependent Protein Catabolic Process Via The Multivesicular Body Sorting Pathway Regulation Of Exosomal Secretion Positive Regulation Of Exosomal Secretion Regulation Of Platelet-derived Growth Factor Receptor Signaling Pathway Late Endosome To Vacuole Transport Via Multivesicular Body Sorting Pathway Flemming Body Multivesicular Body Organization Multivesicular Body Assembly Late Endosome To Vacuole Transport Positive Regulation Of Secretion By Cell Endosome Transport Via Multivesicular Body Sorting Pathway Positive Regulation Of Secretion Membrane Fission Multivesicular Body Sorting Pathway Establishment Of Protein Localization To Vacuole Regulation Of MAP Kinase Activity Receptor Internalization Organelle Localization Response To Desipramine Positive Regulation Of Cellular Component Biogenesis Negative Regulation Of Norepinephrine Uptake Phospholipase D Inhibitor Activity Positive Regulation Of SNARE Complex Assembly Negative Regulation Of Dopamine Uptake Involved In Synaptic Transmission Protein Localization To Vacuole Endosome Organization Regulation Of Vesicle-mediated Transport Regulation Of Phosphorus Metabolic Process Regulation Of Secretion By Cell Ubiquitin Binding Establishment Of Vesicle Localization Regulation Of Secretion Regulation Of Norepinephrine Uptake Negative Regulation Of Mitochondrial Electron Transport, NADH To Ubiquinone Positive Regulation Of Hydrogen Peroxide Catabolic Process Vesicle Localization Lysosomal Transport Regulation Of Protein Serine/threonine Kinase Activity Positive Regulation Of Ubiquitin-dependent Endocytosis Negative Regulation Of Serotonin Uptake Transporter Regulator Activity Positive Regulation Of Endocytosis Negative Regulation Of Chaperone-mediated Autophagy Macroautophagy Positive Regulation Of Viral Budding Via Host ESCRT Complex ESCRT-0 Complex	Intermediate Filament Supramolecular Fiber Organization Intermediate Filament Organization Intermediate Filament Cytoskeleton Organization Keratin Filament Intermediate Filament-based Process Structural Constituent Of Skin Epidermis Protein Binding Cytoskeleton Organization Cytoskeleton Structural Molecule Activity MRNA Alternative Polyadenylation MRNA Cleavage Factor Complex
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