VPS37D

Description		VPS37D subunit of ESCRT-I
Image		No pdb structure
GO Annotations	Cellular Component	ESCRT I Complex Endosome Endosome Membrane Membrane Late Endosome Membrane Extracellular Exosome
	Molecular Function	Protein Binding
	Biological Process	Protein Targeting To Membrane Protein Targeting To Vacuole Protein Transport Macroautophagy Multivesicular Body Assembly Viral Budding Via Host ESCRT Complex Ubiquitin-dependent Protein Catabolic Process Via The Multivesicular Body Sorting Pathway Protein Transport To Vacuole Involved In Ubiquitin-dependent Protein Catabolic Process Via The Multivesicular Body Sorting Pathway Membrane Fission
Pathways		Budding and maturation of HIV virion Membrane binding and targetting of GAG proteins Endosomal Sorting Complex Required For Transport (ESCRT) HCMV Late Events Late endosomal microautophagy
Drugs
Diseases
GWAS		Coffee consumption (cups per day) ( 25288136) Gamma glutamyl transferase levels ( 29403010) Hypertriglyceridemia ( 23505323) Malaria ( 31844061) Serum albumin levels ( 29403010) Serum uric acid levels ( 29403010)
Interacting Genes		5 interacting genes: ARMC7 CEP55 HGS SNCA TSG101
Entrez ID		155382
HPRD ID		19106
Ensembl ID		ENSG00000176428
Uniprot IDs		Q86XT2
PDB IDs
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Exocytosis Negative Regulation Of Platelet-derived Growth Factor Receptor Signaling Pathway Membrane Organization Regulation Of Exocytosis Protein Transport To Vacuole Involved In Ubiquitin-dependent Protein Catabolic Process Via The Multivesicular Body Sorting Pathway Regulation Of Exosomal Secretion Positive Regulation Of Exosomal Secretion Regulation Of Platelet-derived Growth Factor Receptor Signaling Pathway Late Endosome To Vacuole Transport Via Multivesicular Body Sorting Pathway Flemming Body Multivesicular Body Organization Multivesicular Body Assembly Late Endosome To Vacuole Transport Positive Regulation Of Secretion By Cell Endosome Transport Via Multivesicular Body Sorting Pathway Positive Regulation Of Secretion Membrane Fission Multivesicular Body Sorting Pathway Establishment Of Protein Localization To Vacuole Regulation Of MAP Kinase Activity Receptor Internalization Organelle Localization Response To Desipramine Positive Regulation Of Cellular Component Biogenesis Negative Regulation Of Norepinephrine Uptake Phospholipase D Inhibitor Activity Positive Regulation Of SNARE Complex Assembly Negative Regulation Of Dopamine Uptake Involved In Synaptic Transmission Protein Localization To Vacuole Endosome Organization Regulation Of Vesicle-mediated Transport Regulation Of Phosphorus Metabolic Process Regulation Of Secretion By Cell Ubiquitin Binding Establishment Of Vesicle Localization Regulation Of Secretion Regulation Of Norepinephrine Uptake Negative Regulation Of Mitochondrial Electron Transport, NADH To Ubiquinone Positive Regulation Of Hydrogen Peroxide Catabolic Process Vesicle Localization Lysosomal Transport Regulation Of Protein Serine/threonine Kinase Activity Positive Regulation Of Ubiquitin-dependent Endocytosis Negative Regulation Of Serotonin Uptake Transporter Regulator Activity Positive Regulation Of Endocytosis Negative Regulation Of Chaperone-mediated Autophagy Macroautophagy Positive Regulation Of Viral Budding Via Host ESCRT Complex ESCRT-0 Complex
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