KCTD7 and VEZF1

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		KCTD7	VEZF1
Description		potassium channel tetramerization domain containing 7	vascular endothelial zinc finger 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytoplasm Cytosol Plasma Membrane Membrane	Nucleus Nucleoplasm
	Molecular Function	Protein Binding Identical Protein Binding	RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific DNA Binding Protein Binding Zinc Ion Binding Metal Ion Binding
	Biological Process	Intracellular Potassium Ion Homeostasis Protein Homooligomerization Membrane Hyperpolarization Intracellular Glutamate Homeostasis	Angiogenesis Endothelial Cell Development Regulation Of Transcription By RNA Polymerase II Cellular Defense Response Positive Regulation Of Endothelial Cell Differentiation Positive Regulation Of DNA-templated Transcription Positive Regulation Of Transcription By RNA Polymerase II
Pathways		Neddylation Antigen processing: Ubiquitination & Proteasome degradation
Drugs
Diseases
GWAS		Aortic root size ( 21223598) Cotinine glucuronidation ( 25293881) Estimated glomerular filtration rate ( 31152163)	Metabolite levels ( 23823483)
Interacting Genes		44 interacting genes: ADAMTSL4 ATXN7L2 BAG4 CAPN1 CAPN2 CAPNS1 CUL3 DVL3 EFHC2 GAS2L2 GORASP2 INCA1 INO80B KAT5 KRT75 KRTAP13-3 LNX1 MDFI MEOX1 MEOX2 NIF3L1 NTAQ1 NXF1 PARVG PAX6 PIN1 PPARA PRPF18 PRR22 PSMA1 RAB4A REL TCEA2 TCEANC TERF1 TRIM2 TRIM3 UBC VEZF1 ZNF417 ZNF438 ZNF474 ZNF552 ZNF587	65 interacting genes: AGR2 ATXN7L1 BANP C10orf55 CEACAM6 CEP76 DAZAP2 EHMT2 FAM153B FAM168B FOSB FSD2 GOLGA6L9 GPSM1 HIVEP1 HOMEZ HSF2BP HSPB2 HSPB2-C11orf52 INCA1 KCTD7 KRT40 KRTAP10-8 KRTAP19-5 KRTAP8-1 LASP1 LCN2 LHX3 LMO2 LZTS2 MEIS3 MEOX2 MLLT10 MSX2 NCKIPSD NFYA NRF1 OGT PFDN5 PICK1 PLAGL2 POGZ POU6F2 PRKAR1B PRR20A PRR20B PRR20C PRR20D PRR20E RBPMS RUBCN SF3A2 SOX13 SP4 SPAG16 TLE5 TRAF1 TRAF2 TRIM27 TSC1 UBE2I VBP1 VPS52 WWOX ZMYND12
Entrez ID		154881	7716
HPRD ID		13770	08416
Ensembl ID		ENSG00000243335	ENSG00000136451
Uniprot IDs		Q96MP8	J3QSH4 Q14119
PDB IDs
Enriched GO Terms of Interacting Partners?		Calpain Complex Calcium-dependent Cysteine-type Endopeptidase Activity Regulation Of Transcription By RNA Polymerase II Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of DNA-templated Transcription Regulation Of RNA Metabolic Process Regulation Of RNA Biosynthetic Process Somite Specification Proteolysis Involved In Protein Catabolic Process DNA-binding Transcription Factor Activity, RNA Polymerase II-specific	Regulation Of DNA-templated Transcription Identical Protein Binding Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Regulation Of Transcription By RNA Polymerase II Protein Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Regulation Of Nucleobase-containing Compound Metabolic Process Sequence-specific DNA Binding Positive Regulation Of RNA Biosynthetic Process Positive Regulation Of DNA-templated Transcription Prefoldin Complex Phosphatidylinositol 3-kinase Inhibitor Activity Negative Regulation Of Macroautophagy Intermediate Filament Negative Regulation Of Wnt Signaling Pathway
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