MB21D2 and ATXN7L2

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		MB21D2	ATXN7L2
Description		Mab-21 domain containing 2	ataxin 7 like 2
Image			No pdb structure
GO Annotations	Cellular Component
	Molecular Function	Protein Binding Transferase Activity Nucleotidyltransferase Activity Protein-containing Complex Binding Cadherin Binding
	Biological Process
Pathways
Drugs
Diseases
GWAS		Anti-saccade response ( 29064472)	Chronic kidney disease ( 20383146) Intelligence (MTAG) ( 29326435) Major depressive disorder ( 20125088)
Interacting Genes		13 interacting genes: ARHGEF5 ATXN7L2 BYSL CBX8 CIRSR DTNB EVI5 MORN3 RAB3IP REL SLC12A4 SPRY1 SPRY2	27 interacting genes: BAG3 BANP CBX1 CBX3 CTIF CYSRT1 FSD2 GOLGA6L9 HSF2BP HSPB8 IKZF3 KCTD7 KRT31 LAMB1 MB21D2 MDFI PACSIN3 PPP1R16A PPP2R3A PRDM6 RBPMS SBK3 SH3RF1 SH3RF2 SSC4D USP54 ZNF526
Entrez ID		151963	127002
HPRD ID		14092	12506
Ensembl ID		ENSG00000180611	ENSG00000162650
Uniprot IDs		Q8IYB1	A0A804HIT1 A0A804HIX1 A0A804HJY2 Q5T6C5
PDB IDs		7LT1
Enriched GO Terms of Interacting Partners?		Negative Regulation Of Neurotrophin TRK Receptor Signaling Pathway Negative Regulation Of Lens Fiber Cell Differentiation Bud Elongation Involved In Lung Branching Regulation Of Lens Fiber Cell Differentiation Regulation Of Neurotrophin TRK Receptor Signaling Pathway Branch Elongation Of An Epithelium Axis Elongation Negative Regulation Of Fibroblast Growth Factor Receptor Signaling Pathway Negative Regulation Of Ras Protein Signal Transduction Regulation Of Fibroblast Growth Factor Receptor Signaling Pathway Establishment Of Mitotic Spindle Orientation Establishment Of Mitotic Spindle Localization Establishment Of Spindle Orientation Negative Regulation Of Epithelial To Mesenchymal Transition Regulation Of Ras Protein Signal Transduction Negative Regulation Of Epithelial Cell Differentiation Establishment Of Spindle Localization ERK1 And ERK2 Cascade Spindle Localization Negative Regulation Of Small GTPase Mediated Signal Transduction Regulation Of ERK1 And ERK2 Cascade Positive Regulation Of Protein Import Regulation Of Small GTPase Mediated Signal Transduction Negative Regulation Of ERK1 And ERK2 Cascade Lung Growth Ciliary Basal Body-plasma Membrane Docking Myeloid Dendritic Cell Chemotaxis Regulation Of Protein Import Epithelial To Mesenchymal Transition Involved In Cardiac Fibroblast Development	Identical Protein Binding Positive Regulation Of Aggrephagy Positive Regulation Of Catabolic Process Positive Regulation Of Protein Catabolic Process Cellular Response To Unfolded Protein Histone Methyltransferase Binding
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