CNIH3 and CEACAM3

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		CNIH3	CEACAM3
Description		cornichon family AMPA receptor auxiliary protein 3	CEA cell adhesion molecule 3
Image		No pdb structure
GO Annotations	Cellular Component	Endoplasmic Reticulum Membrane Plasma Membrane ER To Golgi Transport Vesicle Membrane Membrane Dendrite AMPA Glutamate Receptor Complex Endoplasmic Reticulum-Golgi Intermediate Compartment Membrane Dendritic Shaft Synapse Postsynaptic Membrane Glutamatergic Synapse	Plasma Membrane Cell Surface Membrane Specific Granule Membrane
	Molecular Function	Signaling Receptor Binding Protein Binding Channel Regulator Activity	Protein Binding Protein Tyrosine Kinase Binding
	Biological Process	Vesicle-mediated Transport Synaptic Transmission, Glutamatergic Regulation Of Membrane Potential Neurotransmitter Receptor Localization To Postsynaptic Specialization Membrane Regulation Of AMPA Receptor Activity	Regulation Of Immune System Process Signal Transduction
Pathways		COPII-mediated vesicle transport Cargo concentration in the ER	Cell surface interactions at the vascular wall Neutrophil degranulation
Drugs
Diseases
GWAS		Cancer ( 29299148) Gut microbiota relative abundance (Streptococcus) ( 33208821) Low density lipoprotein cholesterol levels ( 32154731) Mean corpuscular hemoglobin ( 32888494) Neonatal white matter microstructure ( 33009551) Neutrophil count ( 32888494) Neutrophil percentage of white cells ( 32888494) Opioid dependence ( 26239289) White blood cell count ( 32888494)
Interacting Genes		28 interacting genes: AQP6 BIK CD79A CEACAM3 CLDN20 ERGIC3 FAM210B FNDC9 GPX8 KCNN4 LEUTX LMNA LRRC25 NEMP1 ODF4 PLD3 SLC16A2 SMIM3 SORT1 STOM SUSD3 TMEM14B TMEM237 TMEM31 TMEM52B TMEM80 TMPRSS2 VSIR	8 interacting genes: CEACAM1 CNIH3 CSNK1A1L NINJ1 NINJ2 PMP22 S100A8 SRC
Entrez ID		149111	1084
HPRD ID		08799	16450
Ensembl ID		ENSG00000143786	ENSG00000170956
Uniprot IDs		Q8TBE1	P40198
PDB IDs			6AVZ 6AW0 6AW1 6AW3
Enriched GO Terms of Interacting Partners?		Membrane	Membrane Destabilizing Activity Cell Adhesion Cytolysis Regulation Of Innate Immune Response Leukocyte Migration Involved In Inflammatory Response Cell-cell Adhesion Leukocyte Migration Regulation Of Vascular Permeability Tissue Regeneration Regulation Of Defense Response Cell Migration Ferroptosis S100A8 Complex Regulation Of Immune Response Regulation Of Signal Transduction Regulation Of Tissue Remodeling Plasma Membrane Regulation Of Inflammatory Response Cell Motility Integrin-mediated Signaling Pathway Positive Regulation Of Defense Response Calprotectin Complex Neutrophil Aggregation Negative Regulation Of Natural Killer Cell Mediated Cytotoxicity Directed Against Tumor Cell Target Insulin Receptor Internalization Negative Regulation Of Cytotoxic T Cell Degranulation Regulation Of Cell Communication Negative Regulation Of Hepatocyte Proliferation Regulation Of Signaling Positive Regulation Of Platelet-derived Growth Factor Receptor-beta Signaling Pathway Insulin Catabolic Process Leukocyte Chemotaxis Nervous System Development Regeneration Compact Myelin Peptidyl-cysteine S-nitrosylation Cellular Response To Progesterone Stimulus Cell-cell Signaling Granulocyte Colony-stimulating Factor Signaling Pathway Regulation Of Homophilic Cell Adhesion Toll-like Receptor 4 Binding Connexin Binding Signaling Cellular Response To Peptide Hormone Stimulus Cell-cell Junction Regulation Of Transport Common Myeloid Progenitor Cell Proliferation Cell Junction Regulation Of Immune System Process Leukocyte Chemotaxis Involved In Inflammatory Response
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