SLC19A3 and TMEM14A

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		SLC19A3	TMEM14A
Description		solute carrier family 19 member 3	transmembrane protein 14A
Image
GO Annotations	Cellular Component	Plasma Membrane Membrane	Mitochondrion Endoplasmic Reticulum Endoplasmic Reticulum Membrane Membrane Mitochondrial Membrane
	Molecular Function	Protein Binding Thiamine Transmembrane Transporter Activity Vitamin Transmembrane Transporter Activity	Protein Binding
	Biological Process	Thiamine Diphosphate Biosynthetic Process Thiamine Transport Pyridoxine Transport Thiamine-containing Compound Metabolic Process Vitamin Transport Transmembrane Transport Thiamine Transmembrane Transport	Apoptotic Process Negative Regulation Of Apoptotic Process Negative Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway
Pathways		Vitamin B1 (thiamin) metabolism
Drugs
Diseases
GWAS		Allergic disease (asthma, hay fever and/or eczema) (age of onset) ( 32603359) Allergic disease (asthma, hay fever and/or eczema) (multivariate analysis) ( 32603359) Asthma ( 30929738 31959851) Asthma (childhood onset) ( 30929738) Asthma onset (childhood vs adult) ( 30929738) Obesity-related traits ( 23251661)	Metabolite levels ( 23823483) Perceived intensity of neohesperidin dihydrochalcone ( 31005972) Response to hepatitis B vaccine ( 29534301)
Interacting Genes		15 interacting genes: ARLN C3orf38 CREB3 CREB3L4 CYB561 CYP4F2 FXYD6-FXYD2 LAT PLPPR2 TAB2 THBD TMEM14A TMEM14B TMEM242 ZFPL1	39 interacting genes: AQP6 CLN8 CPLX4 CREB3 CREB3L1 CXCR3 ERBB3 ERBB4 ERGIC3 ERMAP FAM209A FKBP7 IER3IP1 KCNK5 LMNA LRCH1 LXN MMGT1 MTNR1A MTNR1B MUC1 NEMP1 PDZK1IP1 SAR1A SCN3B SERINC2 SLC10A6 SLC18A1 SLC19A3 SLC35H1 SLC7A1 SSMEM1 TMEM14B TMEM179B TMEM31 TMEM51 TMEM80 TMEM86B USP18
Entrez ID		80704	28978
HPRD ID		07311	15522
Ensembl ID		ENSG00000135917	ENSG00000096092
Uniprot IDs		A0A2R8YHG5 Q9BZV2	Q9Y6G1
PDB IDs		8S4U 8S5U 8S5W 8S5Z 8S61 8S62 8XV2 8XV5 8XV9 8Z7R 8Z7S 8Z7T 8Z7U 8Z7V 8Z7W 8Z7X 8Z7Y 9G5K	2LOO 2LOP
Enriched GO Terms of Interacting Partners?			Membrane Negative Regulation Of Apoptotic Process Neuregulin Receptor Activity Negative Regulation Of Programmed Cell Death Melatonin Receptor Activity Transmembrane Transport
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