CILP2 and NWD1

Data Source: HiPPIP (Novel)

		CILP2	NWD1
Name		cartilage intermediate layer protein 2	NACHT and WD repeat domain containing 1
Structure		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Extracellular Region Extracellular Space Extracellular Exosome	Nucleolus Cytoplasm Cytosol
	Molecular Function	Alkaline Phosphatase Activity Dinucleotide Phosphatase Activity	Nucleotide Binding ATP Binding
	Biological Process	None	Positive Regulation Of Gene Expression Negative Regulation Of NF-kappaB Transcription Factor Activity
GWAS		Bipolar disorder ( 31043756 ) Bipolar I disorder ( 31043756 ) Bipolar II disorder ( 31043756 ) Body fat distribution (leg fat ratio) ( 30664634 ) Body fat distribution (trunk fat ratio) ( 30664634 ) Brain morphology (MOSTest) ( 32665545 ) Cholesterol, total ( 20686565 24097068 25961943 ) Fasting triglyceride levels ( 32603185 ) LDL cholesterol ( 20686565 20864672 19060906 18193044 24097068 25961943 18193043 ) LDL cholesterol levels ( 28334899 ) Low density lipoprotein cholesterol levels ( 28548082 ) Postprandial triglyceride levels ( 32603185 ) Pulse pressure ( 27841878 ) Red cell distribution width ( 27863252 ) Refractive error ( 32231278 ) Schizophrenia ( 25056061 29483656 23974872 ) Total cholesterol levels ( 28334899 28548082 ) Triglyceride levels ( 28334899 28548082 ) Triglycerides ( 18193043 18193044 19060906 20686565 20864672 24097068 25961943 ) Type 2 diabetes ( 22885922 28869590 ) Very low density lipoprotein cholesterol levels ( 28548082 )	Response to bronchodilator in chronic obstructive pulmonary disease (change in FEV1) ( 26503814 )
Novel Interactors		6 novel interactors: ANKLE1 NIBAN3 NR2C2AP NWD1 NXNL1 YJEFN3	1 novel interactors: CILP2
Interacting Genes		None recorded	None recorded
Entrez ID		148113	284434
HPRD ID		16714	17337
Ensembl ID		ENSG00000160161	ENSG00000188039
Uniprot IDs		Q8IUL8	Q149M9
PDB IDs		Not available	Not available
GO Terms Enriched among Interactors		None	Dinucleotide Phosphatase Activity Alkaline Phosphatase Activity