CILP2 and NIBAN3

Data Source: HiPPIP (Novel)

		CILP2	NIBAN3
Name		cartilage intermediate layer protein 2	niban apoptosis regulator 3
Structure		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Extracellular Region Extracellular Space Extracellular Exosome	None
GO Annotations	Molecular Function	Alkaline Phosphatase Activity Dinucleotide Phosphatase Activity	Protein Binding
GWAS		Bipolar disorder ( 31043756 ) Bipolar I disorder ( 31043756 ) Bipolar II disorder ( 31043756 ) Body fat distribution (leg fat ratio) ( 30664634 ) Body fat distribution (trunk fat ratio) ( 30664634 ) Brain morphology (MOSTest) ( 32665545 ) Cholesterol, total ( 20686565 24097068 25961943 ) Fasting triglyceride levels ( 32603185 ) LDL cholesterol ( 20686565 20864672 19060906 18193044 24097068 25961943 18193043 ) LDL cholesterol levels ( 28334899 ) Low density lipoprotein cholesterol levels ( 28548082 ) Postprandial triglyceride levels ( 32603185 ) Pulse pressure ( 27841878 ) Red cell distribution width ( 27863252 ) Refractive error ( 32231278 ) Schizophrenia ( 25056061 29483656 23974872 ) Total cholesterol levels ( 28334899 28548082 ) Triglyceride levels ( 28334899 28548082 ) Triglycerides ( 18193043 18193044 19060906 20686565 20864672 24097068 25961943 ) Type 2 diabetes ( 22885922 28869590 ) Very low density lipoprotein cholesterol levels ( 28548082 )	No GWAS studies recorded
Interacting Genes		None recorded	2 interacting genes: BAG3 MDFI
Entrez ID		148113	199786
HPRD ID		16714	16546
Ensembl ID		ENSG00000160161	ENSG00000167483
Uniprot IDs		Q8IUL8	B4DT44 M0QXK3 M0QZV9 M0R0E0 Q86XR2 Q8N894
PDB IDs		Not available	Not available
GO Terms Enriched among Interactors		None	Dorsal/ventral Axis Specification Trophoblast Giant Cell Differentiation Chaperone-mediated Autophagy Negative Regulation Of Protein Targeting To Mitochondrion Protein Carrier Chaperone Striated Muscle Cell Apoptotic Process Protein Transport Along Microtubule Inclusion Body Assembly Positive Regulation Of Aggrephagy Aggresome Assembly Negative Regulation Of Establishment Of Protein Localization To Mitochondrion Alkaline Phosphatase Activity Dinucleotide Phosphatase Activity Adenyl-nucleotide Exchange Factor Activity Cellular Response To Unfolded Protein Positive Regulation Of Protein Export From Nucleus Muscle Cell Apoptotic Process Cell Differentiation Involved In Embryonic Placenta Development Muscle Cell Cellular Homeostasis Spinal Cord Development Regulation Of Protein Export From Nucleus Dynein Intermediate Chain Binding Negative Regulation Of Striated Muscle Cell Apoptotic Process Aggresome Cellular Response To Topologically Incorrect Protein Extrinsic Apoptotic Signaling Pathway In Absence Of Ligand Protein Folding Chaperone Complex Positive Regulation Of Protein Import Into Nucleus Transcription Regulator Inhibitor Activity Protein Sequestering Activity Extrinsic Apoptotic Signaling Pathway Via Death Domain Receptors Regulation Of Protein Targeting To Mitochondrion