DNAH2 and KRABD2

Data Source: HiPPIP (Novel)

		DNAH2	KRABD2
Name		dynein axonemal heavy chain 2	KRAB domain containing 2
Structure			No pdb structure
GO Annotations	Cellular Component	Cytoplasm Cytoskeleton Axonemal Dynein Complex Microtubule Cilium Axoneme Dynein Complex Motile Cilium Sperm Flagellum Inner Dynein Arm Cell Projection 9+2 Motile Cilium	None
	Molecular Function	Nucleotide Binding Microtubule Motor Activity ATP Binding Minus-end-directed Microtubule Motor Activity Dynein Intermediate Chain Binding Dynein Light Intermediate Chain Binding	Nucleic Acid Binding Protein Binding
	Biological Process	Microtubule-based Movement Inner Dynein Arm Assembly Cilium-dependent Cell Motility Cilium Movement Involved In Cell Motility	Regulation Of DNA-templated Transcription DNA Integration
GWAS		Alanine aminotransferase levels ( 34315874 ) Aspartate aminotransferase levels ( 34315874 ) Bitter alcoholic beverage consumption ( 31046077 ) Brain morphology (MOSTest) ( 32665545 ) Height ( 31562340 ) Hematocrit ( 27863252 32888494 ) Hemoglobin ( 32888494 ) Hemoglobin concentration ( 27863252 ) Hemoglobin levels ( 32327693 ) Mean reticulocyte volume ( 32888494 ) Platelet count ( 32888494 ) Plateletcrit ( 27863252 ) Red blood cell count ( 32888494 ) Uterine fibroids ( 30194396 ) White blood cell count ( 27863252 32888494 )	No GWAS studies recorded
Novel Interactors		6 novel interactors: CCDC42 CDK18 KCTD11 KRABD2 ODF4 PIK3R6	2 novel interactors: CNTROB DNAH2
Interacting Genes		1 interacting genes: LINC01554	1 interacting genes: HDAC7
Entrez ID		146754	124751
HPRD ID		17214	14028
Ensembl ID		ENSG00000183914	ENSG00000184619
Uniprot IDs		Q9P225	A8MX02 Q6ZNG9
PDB IDs		8J07	Not available
GO Terms Enriched among Interactors		None	Histone Deacetylase Activity Macromolecule Deacylation Negative Regulation Of Non-canonical NF-kappaB Signal Transduction 14-3-3 Protein Binding Protein Deacetylation SUMO Transferase Activity Positive Regulation Of Cell Migration Involved In Sprouting Angiogenesis Protein Lysine Deacetylase Activity Membraneless Organelle Assembly Negative Regulation Of Interleukin-2 Production Histone Deacetylase Activity, Hydrolytic Mechanism Cellular Component Assembly Organelle Assembly Mitotic Cytokinetic Process Centriole Assembly Centriole Replication Microtubule-based Process Centrosome Separation Inner Dynein Arm 9+2 Motile Cilium Dynein Intermediate Chain Binding Axonemal Dynein Complex Assembly Minus-end-directed Microtubule Motor Activity Inner Dynein Arm Assembly Dynein Light Intermediate Chain Binding Axonemal Dynein Complex Dynein Complex Cytokinetic Process Histone Deacetylase Complex Protein Kinase C Binding Protein Sumoylation Regulation Of Cell Migration Involved In Sprouting Angiogenesis