KRABD2 and DNAH2

Data Source: HiPPIP (Novel)

		KRABD2	DNAH2
Name		KRAB domain containing 2	dynein axonemal heavy chain 2
Structure		No pdb structure
GO Annotations	Cellular Component	None	Cytoplasm Cytoskeleton Axonemal Dynein Complex Microtubule Cilium Axoneme Dynein Complex Motile Cilium Sperm Flagellum Inner Dynein Arm Cell Projection 9+2 Motile Cilium
	Molecular Function	Nucleic Acid Binding Protein Binding	Nucleotide Binding Microtubule Motor Activity ATP Binding Minus-end-directed Microtubule Motor Activity Dynein Intermediate Chain Binding Dynein Light Intermediate Chain Binding
	Biological Process	Regulation Of DNA-templated Transcription DNA Integration	Microtubule-based Movement Inner Dynein Arm Assembly Cilium-dependent Cell Motility Cilium Movement Involved In Cell Motility
GWAS		No GWAS studies recorded	Alanine aminotransferase levels ( 34315874 ) Aspartate aminotransferase levels ( 34315874 ) Bitter alcoholic beverage consumption ( 31046077 ) Brain morphology (MOSTest) ( 32665545 ) Height ( 31562340 ) Hematocrit ( 27863252 32888494 ) Hemoglobin ( 32888494 ) Hemoglobin concentration ( 27863252 ) Hemoglobin levels ( 32327693 ) Mean reticulocyte volume ( 32888494 ) Platelet count ( 32888494 ) Plateletcrit ( 27863252 ) Red blood cell count ( 32888494 ) Uterine fibroids ( 30194396 ) White blood cell count ( 27863252 32888494 )
Novel Interactors		2 novel interactors: CNTROB DNAH2	6 novel interactors: CCDC42 CDK18 KCTD11 KRABD2 ODF4 PIK3R6
Interacting Genes		1 interacting genes: HDAC7	1 interacting genes: LINC01554
Entrez ID		124751	146754
HPRD ID		14028	17214
Ensembl ID		ENSG00000184619	ENSG00000183914
Uniprot IDs		A8MX02 Q6ZNG9	Q9P225
PDB IDs		Not available	8J07
GO Terms Enriched among Interactors		Histone Deacetylase Activity Macromolecule Deacylation Negative Regulation Of Non-canonical NF-kappaB Signal Transduction 14-3-3 Protein Binding Protein Deacetylation SUMO Transferase Activity Positive Regulation Of Cell Migration Involved In Sprouting Angiogenesis Protein Lysine Deacetylase Activity Membraneless Organelle Assembly Negative Regulation Of Interleukin-2 Production Histone Deacetylase Activity, Hydrolytic Mechanism Cellular Component Assembly Organelle Assembly Mitotic Cytokinetic Process Centriole Assembly Centriole Replication Microtubule-based Process Centrosome Separation Inner Dynein Arm 9+2 Motile Cilium Dynein Intermediate Chain Binding Axonemal Dynein Complex Assembly Minus-end-directed Microtubule Motor Activity Inner Dynein Arm Assembly Dynein Light Intermediate Chain Binding Axonemal Dynein Complex Dynein Complex Cytokinetic Process Histone Deacetylase Complex Protein Kinase C Binding Protein Sumoylation Regulation Of Cell Migration Involved In Sprouting Angiogenesis	None