RNF151 and ABT1

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		RNF151	ABT1
Description		ring finger protein 151	activator of basal transcription 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm	Nucleus Transcription Regulator Complex Nucleolus
	Molecular Function	Protein Binding Zinc Ion Binding Enzyme Binding Identical Protein Binding Metal Ion Binding	Nucleic Acid Binding DNA Binding Transcription Coactivator Activity RNA Binding Protein Binding
	Biological Process	Spermatogenesis Cell Differentiation	Endonucleolytic Cleavage In ITS1 To Separate SSU-rRNA From 5.8S RRNA And LSU-rRNA From Tricistronic RRNA Transcript (SSU-rRNA, 5.8S RRNA, LSU-rRNA) Endonucleolytic Cleavage To Generate Mature 5'-end Of SSU-rRNA From (SSU-rRNA, 5.8S RRNA, LSU-rRNA) Endonucleolytic Cleavage In 5'-ETS Of Tricistronic RRNA Transcript (SSU-rRNA, 5.8S RRNA, LSU-rRNA) Regulation Of DNA-templated Transcription Regulation Of Transcription By RNA Polymerase II Transcription By RNA Polymerase II Spinal Cord Motor Neuron Differentiation Small-subunit Processome Assembly Positive Regulation Of DNA-templated Transcription
Pathways
Drugs
Diseases
GWAS		Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098)	A body shape index ( 34021172) Autism spectrum disorder or schizophrenia ( 28540026) Brain morphology (MOSTest) ( 32665545) Fish- and plant-related diet ( 32066663) General cognitive ability ( 29844566) Hip circumference adjusted for BMI ( 34021172) Intelligence (MTAG) ( 29326435) Left-handedness ( 32989287) Lung cancer ( 28604730) Lung cancer in ever smokers ( 28604730) Refractive error ( 32231278) Small cell lung carcinoma ( 28604730) Subcortical volume (MOSTest) ( 32665545) Waist circumference variance ( 31453325) Waist-hip index ( 34021172) Waist-to-hip ratio adjusted for BMI ( 34021172)
Interacting Genes		18 interacting genes: ABT1 APP C1orf35 CT45A1 DVL3 FAM133A FAM9A FGF12 NKAPD1 PIBF1 PRPF3 SCARA5 SREK1IP1 TSPYL2 UBC UBE2D2 UBE2I ZC4H2	16 interacting genes: APP CCDC136 CDCA7L CEP70 DVL3 EMD FAM9B LZTS2 MAB21L3 PICK1 PPP1CC PRNP RNF151 SYNE4 TBP TSPYL2
Entrez ID		146310	29777
HPRD ID		19116	16469
Ensembl ID		ENSG00000179580	ENSG00000146109
Uniprot IDs		H3BNJ8 Q2KHN1	Q9ULW3
PDB IDs
Enriched GO Terms of Interacting Partners?			Neuron Projection Organization Neuron Projection Maintenance Regulation Of Dendritic Spine Maintenance Negative Regulation Of Long-term Synaptic Potentiation Dendritic Spine Maintenance Intracellular Copper Ion Homeostasis Lamin Binding Regulation Of Protein Localization Copper Ion Homeostasis Cellular Response To Copper Ion Negative Regulation Of Canonical Wnt Signaling Pathway Molecular Function Activator Activity Positive Regulation Of Receptor Internalization Amyloid Fibril Formation Response To Copper Ion Negative Regulation Of Wnt Signaling Pathway Frizzled Binding Nuclear Outer Membrane Negative Regulation Of Fibroblast Proliferation Dendritic Spine Organization Negative Regulation Of Protein Localization To Nucleus Amyloid-beta Complex Growth Cone Lamellipodium Reproductive Process Regulation Of Response To Calcium Ion Regulation Of Synaptic Plasticity Amylin Binding Positive Regulation Of Toll Signaling Pathway Regulation Of Long-term Synaptic Potentiation TMEM240-body Male Gamete Generation Spermatogenesis Type 8 Metabotropic Glutamate Receptor Binding Postsynapse Organization Primary Ureteric Bud Growth Developmental Process Involved In Reproduction Cellular Response To Amyloid-beta Regulation Of Amyloid Precursor Protein Catabolic Process Postsynapse Regulation Of Establishment Of Protein Localization Positive Regulation Of Calcium-mediated Signaling Positive Regulation Of Receptor-mediated Endocytosis Cytoplasm Gamete Generation Regulation Of Canonical Wnt Signaling Pathway Response To Amyloid-beta Glial Cell Development Acetylcholine Receptor Activator Activity Positive Regulation Of Neuron Apoptotic Process Lipoprotein Particle
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